Frequency and molecular characterization of isoniazid resistance in katG region of MDR isolates from tuberculosis patients in southern endemic border of Iran

Infection, Genetics and Evolution

Volumn 8, Issue 1, 2008, Pages 15-19

  Zakerbostanabad, Saeed ^a   Titov, Leonid Petrovich ^b   Bahrmand, Ahmad R ^a  

^a PASTEUR INSTITUTE OF IRAN   (Iran)

^b Belarusian Research Institute Microbiology and Epidemiology   (Iran)

Author keywords

Iranian isolates; katG gene mutation; M. tuberculosis

Indexed keywords

ADENINE; ARGININE; ASPARAGINE; CYTOSINE; ETHAMBUTOL; ETHIONAMIDE; GUANINE; ISONIAZID; KANAMYCIN; KATG PROTEIN; RIFAMPICIN; SERINE; STREPTOMYCIN; THREONINE; THYMINE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIUM ISOLATE; CODON; CONTROLLED STUDY; ENDEMIC DISEASE; GENE MUTATION; HUMAN; IRAN; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MOLECULAR BIOLOGY; MULTIDRUG RESISTANCE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PRIORITY JOURNAL; SUPERINFECTION;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; CATALASE; DRUG RESISTANCE, MULTIPLE, BACTERIAL; GENOTYPE; HUMANS; IRAN; ISONIAZID; MUTATION; MYCOBACTERIUM TUBERCULOSIS; POLYMERASE CHAIN REACTION; TUBERCULOSIS, MULTIDRUG-RESISTANT;

MYCOBACTERIUM TUBERCULOSIS;

EID: 36749003758     PISSN: 15671348     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.meegid.2007.09.002     Document Type: Article

References (24)

1. Ahmad S., Fares E., Araj G.F., Chugh T.D., and Mustafa A.S. Prevalence of S315T mutation within the katG gene in isoniazid-resistant clinical Mycobacterium tuberculosis isolates from Dubai and Beirut. Int. J. Tuberc. Lung Dis. 6 10 (2002) 920-926
2. Alexander S.P., Brigitte S.J., and Cole S.T. Effect of katG mutations on the virulence of Mycobacterium tuberculosis and the implication for transmission in humans. Infect. Immun. 70 9 (2002) 4955-4960
3. Ali S., Namaei H.M., Naderinasab M., and Ziaee M. Prevalence of primary drug resistant Mycobacterium tuberculosis in Mashhad, Iran. Indian J. Med. Res. 124 1 (2006) 77-80
4. Bahrmand A.R., Velayati A.A., and Bakayev V.V. Prevalence of drug-resistant Mycobacterium tuberculosis and monitoring therapy in tuberculosis patient in Tehran. Int. J. Tuberc. Lung Dis. 4 (2004) 544-549
5. Herrera L., Molina L., Saiz T., Saez N.P., and Jimenez M.S. New multiplex PCR for rapid detection of isoniazid-resistant Mycobacterium tuberculosis clinical isolates. Antimicrob. Agents Chemother. 49 (2005) 144-147
6. Iseman M.D. Treatment of multidrug-resistant tuberculosis. N. Engl. J. Med. 329 (1993) 784-791
7. Ivanov I., Parinov S., Guschin D., Drobishev A., Dubiley S., and Mirzabekov A. DNA analysis and diagnostics on oligonucleotide microchips. Proc. Natl. Acad. Sci. 93 (1996) 4913-4918
8. Kent P.T., and Kubica G.P. Public health mycobacteriology, a guide for the level III laboratory, CDC, U.S. Department of Health and Human service publication no. (CDC) 86-216546. Atlanta (1985) 21-30
9. Kiepiela P., Bishop K.S., Smith A.N., Roux L., and York D.F. Genomic mutations in the katG, inhA, and ahpC genes are useful for the prediction of isoniazid resistance in Mycobacterium tuberculosis isolates from Kwazulu Natal, South Africa. Tuberc. Lung Dis. 80 (2000) 47-56
10. Kotlowski R., Martin A., Ablordey A., Chemlal K., Fonteyne P.A., and Portaels F. One-tube cell lysis and DNA extraction procedure for PCR-based detection of Mycobacterium ulcerans in aquatic insects, molluscs and fish. J. Med. Microbiol. 53 (2004) 927-933
11. Lin S.Y., Probert W., Lo M., Desmond E.L., Bianchi L., and Tortoli E. Rapid detection of isoniazid and rifampin resistance mutations in Mycobacterium tuberculosis complex from cultures or smear-positive sputa by use of molecular beacons. J. Clin. Microbiol. 42 (2004) 4204-4420
12. Makrousov I., Otten T., Filipenko A., Chrapov E., Limeschenko E., Vyshnevsriyv L., and Narvskaya O. Detection of isoniazid-resistant strain by a multiplex allele-specific PCR assay targeting KatG codon 315 variation. Clin. Microbiol. 40 (2002) 2509-2512
13. Marin M., de Viedma D.G., Ruiz-Serrano M.J., and Bouza E. Rapid direct detection of multiple rifampin and isoniazid resistance mutations in Mycobacterium tuberculosis in respiratory samples by real-time PCR. Antimicrob. Agents Chemother. 48 (2004) 4293-4300
14. Marcia Susana N. Silva, Simone G. Senna, Marta O. Ribeiro, Andreia R.M. Valim, Maria Alice Telles, Afranio Kritski, Glenn P. Morlock, Robert C. Cooksey, Arnaldo Zaha, Maria Lucia R. Rossetti, 2003. Mutations in katG, inhA, and ahpC genes of Brazilian isoniazid-resistant isolates Mycobacterium tuberculosis. J. Clin. Microbiol. 9, 4471-44.
15. Mirsaeidi S.M., Tabarsi P., Khoshnood K., Pooramiri M.V., Rowhani-Rahbar A., Mansoori S.D., Masjedi H., Zahirifard S., Mohammadi F., Farnia P., Masjedi M.R., and Velayati A.A. Treatment of multiple drug-resistant tuberculosis (MDR-TB) in Iran. Int. J. Infect. Dis. 9 6 (2005) 317-322
16. Mokrousov I., Narvskaya O., Otten T., Limeschenko E., Steklova L., and Vyshnevskiy B. High prevalence of KatG Ser315Thr substitution among isoniazid-resistant Mycobacterium tuberculosis clinical isolates from northwestern Russia, 1996 to 2001. Antimicrob. Agents Chemother. 46 (2002) 1417-1424
17. Narvskaya O., Mokrousov I., Otten T., Filipenko M., Vyazovaya A., Chrapov E., Limeschenko E., Steklova L., and Vyshnevskiy B. Detection of isoniazid-resistant Mycobacterium tuberculosis strains by a multiplex allele-specific PCR assay targeting katG codon 315 variation. J. Clin. Microbiol. 40 7 (2002) 2509-2512
18. Ruiz M., Torres M.J., Llanos A.C., Arroyo A., Palomares J.C., and Aznar J. Direct detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis in auramine-rhodamine-positive sputum specimens by real-time PCR. J. Clin. Microbiol. 42 (2004) 1585-1589
19. Slayden R.A., and Barry C.E. The role of KasA and KasB in the biosynthesis of meromycolic acids and isoniazid resistance in Mycobacterium tuberculosis. Tuberculosis 82 4/5 (2002) 149-160
20. Telenti A., Imboden P., Marchesi F., Lowrie D., Cole S., Colston M.J., Matter L., Schopfer K., and Bodmer T. Detection of rifampicin-resistance mutations in Mycobacterium tuberculosis. Lancet 341 (1993) 647-650
21. Telenti A., Honore N., Brenasconi C., March J., Ortega H.T., and Cole S.T. Genotyping assessment of isoniazid and rifmpicine resistance in Mycobacterium tuberculosis: a blind study at reference laboratory level. J. Clin. Microbiol. 35 (1997) 719-723
22. Tung-Yiu Leung E., Kai-Man K., Chiu A., Pak Leung H., Wing-Hong S., Kwok-Yung Y., and Wing-Cheong Y. Detection of katG Ser315The substitution in respiratory specimens from patinas with isoniazid-resistant Mycobacterium tuberculosis using PCR-RFLP. J. Med. Microbiol. 52 (2003) 999-1003
23. Velayati A.A., and Mohammadi M. Childhood respiratory tuberculosis in Iran. Med. J. Islamic Republic Iran 4 (1990) 1-4
24. Zaker S.B., Titov L.P., Bahrmand A.R., and Taghikhani M. Genetic mechanicm of Mycobacterium tuberculosis resistance to antituberculsis drugs, isoniazid and rifampicine. J. Dakladi Hational Akademia Sci. Belarus 50 6 (2006) 92-98