The type I interferon system protects mice from Semliki Forest virus by preventing widespread virus dissemination in extraneural tissues, but does not mediate the restricted replication of avirulent virus in central nervous system neurons

Journal of General Virology

Volumn 88, Issue 12, 2007, Pages 3373-3384

  Fragkoudis, Rennos ^a   Breakwell, Lucy ^a   McKimmie, Clive ^a   Boyd, Amanda ^a   Barry, Gerald ^a   Kohl, Alain ^a   Merits, Andres ^b   Fazakerley, John K ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

^b UNIVERSITY OF TARTU   (Estonia)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTERFERON;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BIOTECHNOLOGY; CENTRAL NERVOUS SYSTEM; EMBRYO; ENCEPHALITIS; ENDOCARDIUM; EPENDYMA CELL; GENE ACTIVATION; GENE EXPRESSION; HEART MUSCLE; HISTOPATHOLOGY; HOST RESISTANCE; HUMORAL IMMUNITY; IN SITU HYBRIDIZATION; INTERFERON PRODUCTION; MOUSE; NEWBORN; NONHUMAN; OLIGODENDROGLIA; ORGAN DISTRIBUTION; PANCREAS; PATHOGENESIS; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEMLIKI FOREST ALPHAVIRUS; SMOOTH MUSCLE FIBER; VIRUS ENCEPHALITIS; VIRUS INFECTION; VIRUS REPLICATION; VIRUS RESISTANCE; VIRUS STRAIN; VIRUS VIRULENCE;

ALPHAVIRUS INFECTIONS; ANIMALS; CENTRAL NERVOUS SYSTEM; GENES; INTERFERON TYPE I; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; NEURONS; RECEPTOR, INTERFERON ALPHA-BETA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEMLIKI FOREST VIRUS; VIRAL LOAD; VIRULENCE;

ALPHAVIRUS; MUS; RABBIT FIBROMA VIRUS; SEMLIKI FOREST VIRUS;

EID: 36749002625     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.83191-0     Document Type: Article

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