Comparison of radioimmunoassay and chemiluminescent assay methods to estimate canine blood cortisol concentrations

Australian Veterinary Journal

Volumn 85, Issue 12, 2007, Pages 487-494

  Russell, N J ^a,b   Foster, S ^a   Clark, P ^a   Robertson, I D ^c   Lewis, D ^a   Irwin, P J ^a  

^a MURDOCH UNIVERSITY   (Australia)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Assays; Blood cortisol; Chemiluminescence; Dog; Radioimmunoassay

Indexed keywords

CORTICOTROPIN; HYDROCORTISONE;

ADRENAL CORTEX HYPERFUNCTION; ANIMAL; ANIMAL DISEASE; ARTICLE; BLOOD; BLOOD SAMPLING; BLOOD STORAGE; CHEMOLUMINESCENCE; COMPARATIVE STUDY; DOG; DOG DISEASE; DOSE RESPONSE; METHODOLOGY; RADIOIMMUNOASSAY; REFERENCE VALUE; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; STANDARD; TIME; VALIDATION STUDY;

ADRENOCORTICAL HYPERFUNCTION; ADRENOCORTICOTROPIC HORMONE; ANIMALS; BLOOD PRESERVATION; BLOOD SPECIMEN COLLECTION; CHEMILUMINESCENT MEASUREMENTS; DOG DISEASES; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HYDROCORTISONE; RADIOIMMUNOASSAY; REFERENCE VALUES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

CANIS FAMILIARIS;

EID: 36649035974     PISSN: 00050423     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1751-0813.2007.00232.x     Document Type: Article

References (33)

1. Feldman EC. Comparison of ACTH response and dexamethasone suppression as screening tests in canine hyperadrenocorticism. J Am Vet Med Assoc 1983 182 : 506 510.
2. Feldman EC, Nelson RW, Feldman MS. Use of low- and high-dose dexamethasone tests for distinguishing pituitary-dependent from adrenal tumor hyperadrenocorticism in dogs. J Am Vet Med Assoc 1996 209 : 772 775.
3. Feldman EC. Distinguishing dogs with functioning adrenocortical tumors from dogs with pituitary-dependent hyperadrenocorticism. J Am Vet Med Assoc 1983 183 : 195 200.
4. Rijnberk A, van Wees A, Mol JA. Assessment of two tests for the diagnosis of canine hyperadrenocorticism. Vet Rec 1988 122 : 178 180.
5. Smiley LE, Peterson ME. Evaluation of a urine cortisol:creatinine ratio as a screening test for hyperadrenocorticism in dogs. J Vet Intern Med 1993 7 : 163 168.
6. Feldman EC, Mack RE. Urine cortisol:creatinine ratio as a screening test for hyperadrenocorticism in dogs. J Am Vet Med Assoc 1992 200 : 1637 1641.
7. Kaplan AJ, Peterson ME, Kemppainen RJ. Effects of disease on the results of diagnostic tests for use in detecting hyperadrenocorticism in dogs. J Am Vet Med Assoc 1995 207 : 445 451.
8. Van Liew CH, Greco DS, Salman MD. Comparison of results of adrenocorticotropic hormone stimulation and low-dose dexamethasone suppression tests with necropsy findings in dogs: 81 cases (1985-1995). J Am Vet Med Assoc 1997 211 : 322 325.
9. Reimers TJ, Cowan RG, Davidson HP et al. Validation of radioimmunoassay for triiodothyronine, thyroxine, and hydrocortisone (cortisol) in canine, feline, and equine sera. Am J Vet Res 1981 42 : 2016 2021.
10. Reimers TJ, Salerno VJ, Lamb SV. Validation and application of solid-phase chemiluminescent immunoassays for diagnosis of endocrine diseases in animals. Comp Haematol Int 1996 6 : 170 175.
11. Reimers TJ. Radioimmunoassays and diagnostic tests for thyroid and adrenal disorders. Compend Contin Educ Pract Vet 1982 4 : 65 75.
12. Singh AK, Jiang Y, White T, Spassova D. Validation of nonradioactive chemiluminescent immunoassay methods for the analysis of thyroxine and cortisol in blood samples obtained from dogs, cats, and horses. J Vet Diagn Invest 1997 9 : 261 268.
13. Meyer HP, Rothuizen J. Determination of the percentage of free cortisol in plasma in the dog by ultrafiltration/dialysis. Domest Anim Endocrinol 1993 10 : 45 53.
14. Ginel PJ, Perez-Rico A, Moreno P, Lucena R. Validation of a commercially available enzyme-linked immunosorbent assay (ELISA) for the determination of cortisol in canine plasma samples. Vet Res Commun 1998 22 : 179 185.
15. Jerico MM, Mendonca BB, Otsuka M, Maganin-Junior A, Larsson CE. Non-radiometric immunoassays [fluoroimmunoassay (FIA) and fluorometric enzyme immunoassay (FEIA)] with radioimmunoassay (RIA) for evaluation of adrenal function in normal and hypercortisolemic dogs. Ciencia Rural 2002 32 : 259 262.
16. Watson AD, Church DB, Emslie DR. Plasma cortisol concentrations in dogs given cortisone or placebo by mouth. Res Vet Sci 1993 55 : 379 381.
17. Watson AD, Church DB, Emslie DR, Foster SF. Plasma cortisol responses to three corticotrophic preparations in normal dogs. Aust Vet J 1998 76 : 255 257.
18. Foster SF, Church DB, Watson AD. Effect of phenobarbitone on the low-dose dexamethasone suppression test and the urinary corticoid: creatinine ratio in dogs. Aust Vet J 2000 78 : 19 23.
19. Behrend EN, Kemppainen RJ. Diagnosis of canine hyperadrenocorticism. Vet Clin North Am Small Anim Pract 2001 31 : 985 1003, viii.
20. Feldman EC, Nelson RW. Canine Hyperadrenocorticism (Cushing's Syndrome). In : Nelson RW, Feldman EC, editors. Canine and Feline Endocrinology and Reproduction, 3rd edn. Saunders, St. Louis, 2004 : 252 357.
21. Reusch C. Hyperadrenocorticism. In : Ettinger SJ, Feldman EC, editor Textbook of Veterinary Internal Medicine: Diseases of the dog and cat, 6th edn. Elsevier Saunders, St. Louis, 2005 : 1592 1611.
22. Feldman EC, Nelson RW. Chapter 5 Hyperadrenocorticism. In : Feldman EC, Nelson RW, editor Canine and Feline Endocrinology and Reproduction. W.B. Saunders, Philadelphia, 1987 : 137 194.
23. Peterson ME. Hyperadrenocorticism. Vet Clin North Am Small Anim Pract 1984 14 : 731 749.
24. Braddock JA, Church DB, Robertson ID, Watson AD. Trilostane treatment in dogs with pituitary-dependent hyperadrenocorticism. Aust Vet J 2003 81 : 600 607.
25. Behrend EN, Kemppainen RJ, Young DW. Effect of storage conditions on cortisol, total thyroxine, and free thyroxine concentrations in serum and plasma of dogs. J Am Vet Med Assoc 1998 212 : 1564 1568.
26. Reimers TJ, McCann JP, Cowan RG, Concannon CW. Effects of storage, haemolysis, and freezing and thawing on concentrations of thyroxine, cortisol, and insulin in blood samples. Proc Soc Exp Biol Med 1982 170 : 509 516.
27. Reimers TJ, Lamb SV, Bartlett SA, et al. Effects of haemolysis and storage on quantification of hormones in blood samples from dogs, cattle, and horses. Am J Vet Res 1991 52 : 1075 1080.
28. Lee DE, Lamb SV, Reimers TJ. Effects of hyperlipaemia on radioimmunoassays for progesterone, testosterone, thyroxine, and cortisol in serum and plasma samples from dogs. Am J Vet Res 1991 52 : 1489 1491.
29. Lucena R, Moreno P, Perez-Rico A, Ginel PJ. Effects of haemolysis, lipaemia and bilirubinaemia on an enzyme-linked immunosorbent assay for cortisol and free thyroxine in serum samples from dogs. Vet J 1998 156 : 127 131.
30. Ristic JM, Ramsey IK, Heath EM, Evans HJ, Herrtage ME. The use of 17-hydroxyprogesterone in the diagnosis of canine hyperadrenocorticism. J Vet Intern Med 2002 16 : 433 439.
31. Syme HM, Scott-Moncrieff JC, Treadwell NG et al. Hyperadrenocorticism associated with excessive sex hormone production by an adrenocortical tumor in two dogs. J Am Vet Med Assoc 2001 219 : 1707 1728.
32. Norman EJ, Thompson H, Mooney CT. Dynamic adrenal function testing in eight dogs with hyperadrenocorticism associated with adrenocortical neoplasia. Vet Rec 1999 144 : 551 554.
33. Chapman PS, Mooney CT, Ede J et al. Evaluation of the basal and post-adrenocorticotrophic hormone serum concentrations of 17-hydroxyprogesterone for the diagnosis of hyperadrenocorticism in dogs. Vet Rec 2003 153 : 771 775.