메뉴 건너뛰기




Volumn 14, Issue 2, 2007, Pages 61-65

Addition of lenalidomide to melphalan in the treatment of newly diagnosed multiple myeloma: The National Cancer Institute of Canada Clinical Trials Group MY. 11 trial

Author keywords

Lenalidomide; Melphalan; Multiple myeloma; Newly diagnosed; Thalidomide

Indexed keywords

ACETYLSALICYLIC ACID; ANTINEOPLASTIC AGENT; CORTICOSTEROID; DEXAMETHASONE; GRANULOCYTE COLONY STIMULATING FACTOR; HEPARIN; LENALIDOMIDE; LOW MOLECULAR WEIGHT HEPARIN; MELPHALAN; PLACEBO; PREDNISONE; THALIDOMIDE; WARFARIN;

EID: 36649026598     PISSN: None     EISSN: 17187729     Source Type: Journal    
DOI: 10.3747/co.2007.107     Document Type: Article
Times cited : (7)

References (22)
  • 1
    • 0003472959 scopus 로고
    • eds, Bethesda, MD: National Cancer Institute, Division of Cancer Prevention and Control, Surveillance, Epidemiology, and End Results Program;
    • Ries LAG, Hankey BF, Miller BA, et al., eds. Cancer Statistics Review 1973-88. Bethesda, MD: National Cancer Institute, Division of Cancer Prevention and Control, Surveillance, Epidemiology, and End Results Program; 1991.
    • (1991) Cancer Statistics Review 1973-88
  • 2
    • 0002482560 scopus 로고
    • The survival time of patients with plasmocytic myeloma
    • Osgood EE. The survival time of patients with plasmocytic myeloma. Cancer Chemother Rep 1960;9:1-10.
    • (1960) Cancer Chemother Rep , vol.9 , pp. 1-10
    • Osgood, E.E.1
  • 3
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
    • Palumbo A, Bringhen S, Caravita T, et al. Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial. Lancet 2006;367: 825-31.
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 4
    • 51749111242 scopus 로고    scopus 로고
    • Facon T, Mary J, Harousseau J, et al., on behalf of the Intergroupe Francophone du Myelome. Superiority of melphalan-prednisone (MP) ± thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma [abstract 1]. J Clin Oncol 2006;24(pt 1 suppl 18S):1s.
    • Facon T, Mary J, Harousseau J, et al., on behalf of the Intergroupe Francophone du Myelome. Superiority of melphalan-prednisone (MP) ± thalidomide (THAL) over MP and autologous stem cell transplantation in the treatment of newly diagnosed elderly patients with multiple myeloma [abstract 1]. J Clin Oncol 2006;24(pt 1 suppl 18S):1s.
  • 5
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996;335:91-7.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 6
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003;348:1875-83.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3
  • 7
    • 33644824325 scopus 로고    scopus 로고
    • High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: Long term results of a randomized controlled trial from the Group Myelome-Autogreffe
    • Fermand JP, Katsahian S, Divine M, et al. High-dose therapy and autologous blood stem-cell transplantation compared with conventional treatment in myeloma patients aged 55 to 65 years: long term results of a randomized controlled trial from the Group Myelome-Autogreffe. J Clin Oncol 2005;23: 9227-33.
    • (2005) J Clin Oncol , vol.23 , pp. 9227-9233
    • Fermand, J.P.1    Katsahian, S.2    Divine, M.3
  • 8
    • 33644920953 scopus 로고    scopus 로고
    • Standard chemotherapy compared with high-dose chemotherapy for multiple myeloma: Final results of phase III in US Intergroup Trial S9321
    • Barlogie B, Kyle RA, Anderson KC, et al. Standard chemotherapy compared with high-dose chemotherapy for multiple myeloma: final results of phase III in US Intergroup Trial S9321. J Clin Oncol 2006;24:929-36.
    • (2006) J Clin Oncol , vol.24 , pp. 929-936
    • Barlogie, B.1    Kyle, R.A.2    Anderson, K.C.3
  • 10
    • 0032748385 scopus 로고    scopus 로고
    • Antitumour activity of thalidomide in refractory multiple myeloma
    • Singhal S, Mehta J, Desikan R, et al. Antitumour activity of thalidomide in refractory multiple myeloma. N Engl J Med 1999;341:1565-71.
    • (1999) N Engl J Med , vol.341 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 11
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • Richardson PG, Schlossman RL, Weller E, et al. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood 2002;100:3063-7.
    • (2002) Blood , vol.100 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3
  • 12
    • 1842619774 scopus 로고    scopus 로고
    • A multi-centre, randomized, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma [abstract]
    • Richardson PG, Jagannath S, Schlossman R, et al. A multi-centre, randomized, phase 2 study to evaluate the efficacy and safety of 2 CDC-5013 dose regimens when used alone or in combination with dexamethasone for the treatment of relapsed or refractory multiple myeloma [abstract]. Blood 2003;102: 825a.
    • (2003) Blood , vol.102
    • Richardson, P.G.1    Jagannath, S.2    Schlossman, R.3
  • 13
    • 13944253830 scopus 로고    scopus 로고
    • Revlimid 25 mg × 20 versus 50 mg × 10 q 28 days with bridging of 5 mg × 10 versus 10 mg × 5 as post-transplant salvage therapy for multiple myeloma [abstract]
    • Zangari M, Barlogie B, Jacobson J, et al. Revlimid 25 mg × 20 versus 50 mg × 10 q 28 days with bridging of 5 mg × 10 versus 10 mg × 5 as post-transplant salvage therapy for multiple myeloma [abstract]. Blood 2003;102:1642a.
    • (2003) Blood , vol.102
    • Zangari, M.1    Barlogie, B.2    Jacobson, J.3
  • 14
    • 51749110297 scopus 로고    scopus 로고
    • Wang M, Knight R, Dimopoulos M, et al. Comparison of lenalidomide in combination with dexamethasone to dexamethasone alone in patients who have received prior thalidomide in relapsed or refractory multiple myeloma [abstract 7522]. J Clin Oncol 2006;24(pt 1 suppl 18S)):427s.
    • Wang M, Knight R, Dimopoulos M, et al. Comparison of lenalidomide in combination with dexamethasone to dexamethasone alone in patients who have received prior thalidomide in relapsed or refractory multiple myeloma [abstract 7522]. J Clin Oncol 2006;24(pt 1 suppl 18S)):427s.
  • 15
    • 42649128206 scopus 로고    scopus 로고
    • Melphalan, prednisone and lenalidomide combination (MPR) for newly diagnosed multiple myeloma patients who are not candidates for stem cell transplantation [abstract]
    • Roy V, Bergsagel PL, Allred J, Greipp R. Melphalan, prednisone and lenalidomide combination (MPR) for newly diagnosed multiple myeloma patients who are not candidates for stem cell transplantation [abstract]. Blood 2006;108:1016a.
    • (2006) Blood , vol.108
    • Roy, V.1    Bergsagel, P.L.2    Allred, J.3    Greipp, R.4
  • 16
    • 33750708737 scopus 로고    scopus 로고
    • Oral enalidomide plus melphalan and prednisone (R-MP) for newly diagnosed multiplemyeloma [abstract 7518]
    • 426s
    • Palumbo A, Falco P, Benevolo G, et al. Oral enalidomide plus melphalan and prednisone (R-MP) for newly diagnosed multiplemyeloma [abstract 7518]. J Clin Oncol2006;24(pt 1 suppl 18S):426s.
    • (2006) J Clin Oncol , vol.24 , Issue.PART 1
    • Palumbo, A.1    Falco, P.2    Benevolo, G.3
  • 17
    • 0036566201 scopus 로고    scopus 로고
    • Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients
    • Berenson JR, Crowley JJ, Grogan TM, et al. Maintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients. Blood 2002;99:3163-8.
    • (2002) Blood , vol.99 , pp. 3163-3168
    • Berenson, J.R.1    Crowley, J.J.2    Grogan, T.M.3
  • 18
    • 33845899121 scopus 로고    scopus 로고
    • A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7
    • Shustik C, Belch A, Robinson S, et al. A randomised comparison of melphalan with prednisone or dexamethasone as induction therapy and dexamethasone or observation as maintenance therapy in multiple myeloma: NCIC CTG MY.7. Brit J Haematol 2007;136:203-11.
    • (2007) Brit J Haematol , vol.136 , pp. 203-211
    • Shustik, C.1    Belch, A.2    Robinson, S.3
  • 19
    • 33748940534 scopus 로고    scopus 로고
    • Lenalidomide plus high-dose dexamethasone provides improved overall survival compared to high-dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): Results of a North American phase III in study (MM-009) [abstract 7521]
    • 427s
    • Weber DM, Chen C, Niesvizky R, et al. Lenalidomide plus high-dose dexamethasone provides improved overall survival compared to high-dose dexamethasone alone for relapsed or refractory multiple myeloma (MM): results of a North American phase III in study (MM-009) [abstract 7521]. J Clin Oncol 2006;24(pt 1 suppl 18S):427s.
    • (2006) J Clin Oncol , vol.24 , Issue.PART 1
    • Weber, D.M.1    Chen, C.2    Niesvizky, R.3
  • 20
    • 4644288189 scopus 로고    scopus 로고
    • Geerts Wh, Pineo GF, Heit JA, et al. Prevention of venous thromboembolism: the Seventh ACCP Conference on Anti-thrombotic and Thrombolytic Therapy. Chest 2004; 126(suppl):3385-400S.
    • Geerts Wh, Pineo GF, Heit JA, et al. Prevention of venous thromboembolism: the Seventh ACCP Conference on Anti-thrombotic and Thrombolytic Therapy. Chest 2004; 126(suppl):3385-400S.
  • 21
    • 0034655567 scopus 로고    scopus 로고
    • Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial
    • Prevention of pulmonary embolism and deep vein thrombosis with low dose aspirin: Pulmonary Embolism Prevention (PEP) trial. Lancet 2000;355:1295-302.
    • (2000) Lancet , vol.355 , pp. 1295-1302
  • 22
    • 0007911602 scopus 로고
    • reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists' Collaboration
    • Collaborative overview of randomised trials of antiplatelet therapy, III
    • Collaborative overview of randomised trials of antiplatelet therapy - III: reduction in venous thrombosis and pulmonary embolism by antiplatelet prophylaxis among surgical and medical patients. Antiplatelet Trialists' Collaboration. BMJ 1994; 308:235-46.
    • (1994) BMJ , vol.308 , pp. 235-246


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.