Combining cisplatin with cationized catalase decreases nephrotoxicity while improving antitumor activity

Kidney International

Volumn 72, Issue 12, 2007, Pages 1474-1482

  Ma, S F ^a   Nishikawa, M ^a   Hyoudou, K ^a   Takahashi, R ^a   Ikemura, M ^a   Kobayashi, Y ^a   Yamashita, F ^a   Hashida, M ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

Catalase; Cationization; Cisplatin; Nephrotoxicity; Renal delivery

Indexed keywords

CATALASE; CISPLATIN; CREATININE; GLUTATHIONE; LACTATE DEHYDROGENASE; MALONALDEHYDE; NITRATE; NITRITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; CANCER SURVIVAL; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DRUG EFFICACY; DRUG FATALITY; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; KIDNEY; KIDNEY TUBULE NECROSIS; LOW DRUG DOSE; MALE; MOUSE; NEPHROTOXICITY; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; UREA NITROGEN BLOOD LEVEL;

EID: 36649024984     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/sj.ki.5002556     Document Type: Article

References (43)

1. Terheggen PM, Floot BG, Scherer E et al. Immunocytochemical detection of interaction products of cis-diamminedichloroplatinum (II) and cis-diammine(1, 1-cyclobutanedicarboxylato)-platinum (II) with DNA in rodent tissue sections. Cancer Res 1987; 47: 6717-6725.
2. Lieberthal W, Triaca V, Levine J. Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis. Am J Physiol 1996; 270: F700-F708.
3. Sugihara K, Gemba M. Modification of cisplatin toxicity by antioxidants. Jpn J Pharmacol 1986; 40: 353-355.
4. Sadzuda Y, Shoji T, Takino Y. Mechanism of the increase in lipid peroxide induced by cisplatin in the kidneys of rats. Toxicol Lett 1992; 62: 293-300.
5. Baliga R, Zhang Z, Baliga M et al. In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity. Kidney Int 1998; 53: 394-401.
6. Sadzuda Y, Shoji T, Takino Y et al. Protection against cisplatin-induced nephrotoxicity in the rat by inducers and an inhibitor of glutathione S-transferase. Biochem Pharmacol 1994; 48: 453-459.
7. Anand AJ, Bashey B. Newer insights into cisplatin nephrotoxicity. Ann Pharmacother 1993; 27: 1519-1525.
8. Nishikawa M, Nagatomi H, Nishijima M et al. Targeting superoxide dismutase to renal proximal tubule cells inhibits nephrotoxicity of cisplatin an increases the survival of cancer-bearing. Cancer Lett 2001; 171: 133-138.
9. Turrens JF, Crapo JD, Freeman BA. Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase. J Clin Invest 1984; 73: 87-95.
10. Yabe Y, Nishikawa M, Tamada A et al. Targeted delivery an improved therapeutic potential of catalase by chemical modification: combination with superoxide dismutase derivatives. J Pharmacol Exp Ther 1999; 289: 1176-1184.
11. Yabe Y, Koyama Y, Nishikawa M et al. Hepatocyte-specific distribution of catalase and its inhibitory effect on hepatic ischemia/reperfusion injury in mice. Free Radic Res 1999; 30: 265-274.
12. Yabe Y, Kobayashi N, Nishihashi T et al. Prevention of neutrophil-mediated hepatic ischemia/reperfusion injury by superoxide dismutase and catalase derivatives. J Pharmacol Exp Ther 2001; 298: 894-899.
13. Yabe Y, Kobayashi N, Nishikawa M et al. Pharmacokinetics and preventive effects of targeted catalase derivatives on hydrogen peroxide-induced injury in perfused rat liver. Pharm Res 2002; 19: 1815-1821.
14. Ma SF, Nishikawa M, Katsumi H et al. Liver targeting of catalase by cationization for prevention of acute liver failure in mice. J Control Release 2006; 110: 273-282.
15. Nishikawa M, Tamada A, Hyoudou K et al. Inhibition of experimental hepatic metastasis by targeted delivery of catalase in mice. Clin Exp Metastasis 2004; 21: 213-221.
16. Nishikawa M, Hyoudou K, Kobayashi Y et al. Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes. J Control Release 2005; 109: 101-107.
17. Nishikawa M, Hashida M. Inhibition of tumour metastasis by targeted delivery of antioxidant enzymes. Expert Opin Drug Deliv 2006; 3: 355-369.
18. Nishikawa M, Tamada A, Kumai H et al. Inhibition of experimental pulmonary metastasis by controlling biodistribution of catalase in mice. Int J Cancer 2002; 99: 474-479.
19. Hyoudou K, Nishikawa M, Umeyama Y et al. Inhibition of metastatic tumor growth in mouse lung by repeated administration of polyethylene glycol-conjugated catalase: quantitative analysis with firefly luciferase-expressing melanoma cells. Clin Cancer Res 2004; 10: 7685-7691.
20. Hyoudou K, Nishikawa M, Umeyama Y et al. Pegylated catalase prevents metastatic tumor growth aggravated by tumor removal. Free Radic Biol Med 2006; 41: 1449-1458.
21. Hyoudou K, Nishikawa M, Kobayashi Y et al. Inhibition of adhesion and proliferation of peritoneally disseminated tumor cells by pegylated catalase. Clin Exp Metastasis 2006; 23: 269-278.
22. Brenner BM, Hostetter TH, Humes HD. Glomerular permselectivity: barrier function based on discrimination of molecular size and charge. Am J Physiol 1978; 234: F455-F460.
23. Gonzalez VM, Fuertes MA, Alonso C et al. Is cisplatin-induced cell death always produced by apoptosis? Mol Pharmacol 2001; 59: 195-201.
24. Baliga R, Ueda N, Walker PD et al. Oxidant mechanisms in toxic acute renal failure. Drug Metab Rev 1999; 31: 971-997.
25. 2 production in cisplatin-induced nephrotoxicity. Biochem Biophys Res Commun 1998; 242: 310-312.
26. Baek SM, Kwon CH, Kim JH et al. Differential roles of hydrogen peroxide and hydroxyl radical in cisplatin-induced cell death in renal proximal tubular epithelial cells. J Lab Clin Med 2003; 142: 178-186.
27. Mihara K, Oka Y, Sawai K et al. Improvement of therapeutic effect of human recombinant superoxide dismutase on ischemic acute renal failure in the rat via cationization and conjugation with polyethylene glycol. J Drug Target 1994; 2: 317-321.
28. Mihara K, Sawai K, Takakura Y et al. Manipulation of renal disposition of human recombinant superoxide dismutase by chemical modification. Biol Pharm Bull 1994; 17: 296-301.
29. Simbulan-Rosenthal CM, Rosenthal DS, Ding R et al. Prolongation of the p53 response to DNA strand breaks in cells depleted of PARP by antisense RNA expression. Biochem Biophys Res Commun 1998; 253: 864-868.
30. Racz I, Tory K, Gallyas Jr F et al. BGP-15 - a novel poly(ADP-ribose) polymerase inhibitor - protects against nephrotoxicity of cisplatin without compromising its antitumor activity. Biochem Pharmacol 2002; 63: 1099-1111.
31. Allen RG, Tresini M. Oxidative stress and gene regulation. Free Radic Biol Med 2000; 28: 463-499.
32. Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18: 775-794.
33. 2 for platelet-derived growth factor signal transduction. Science 1995; 270: 296-299.
34. Arnold RS, Shi J, Murad E et al. Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc Natl Acad Sci USA 2001; 98: 5550-5555.
35. Hyoudou K, Nishikawa M, Kobayashi Y et al. Inhibition of peritoneal dissemination of tumor cells by cationized catalase in mice. J Control Release 2007; 119: 117-121.
36. Hyoudou K, Nishikawa M, Ikemura M et al. Cationized catalase-loaded hydrogel for growth inhibition of peritonically disseminated tumor cells. J Control Release 2007 (in press).
37. Baliga R, Zhang Z, Baliga M et al. In vitro and in vivo evidence suggesting a role for iron in cisplatin-induced nephrotoxicity. Kidney Int 1998; 53: 394-401.
38. Ozen S, Akyol O, Iraz M et al. Role of caffeic acid phenethyl ester, an active component of propolis, against cisplatin-induced nephrotoxicity in rats. J Appl Toxicol 2004; 24: 27-35.
39. Ellman GL. Tissue sulfhydryl groups. Biochem Biophys 1959; 82: 70-77.
40. Wasowicz W, Neve J, Peretz A. Optimized steps in fluorometric determination of thiobarbituric acid-reactive substances in serum: importance of extraction pH and influence of sample preservation and storage. Clin Chem 1993; 39: 2522-2526.
41. Coulombe JJ, Favreau L. A new simple semimicro method for colorimetric determination of urea. Clin Chem 1963; 9: 102-108.
42. Bonsnes RW, Taussky HH. On the colorimetric determination of creatinine by the Jaffe reaction. J Biol Chem 1945; 158: 581-591.
43. Poste G, Doll J, Hart IR et al. In vitro selection of murine B16 melanoma variants with enhanced tissue-invasive properties. Cancer Res 1980; 40: 1636-1644.