The correlation between 1H-MR spectroscopy and clinical manifestation with tuberous sclerosis complex

Neuropediatrics

Volumn 38, Issue 3, 2007, Pages 126-129

  Matsuo, N ^a,b   Imamura, A ^b   Ito, R ^b   Sugawara, K ^b   Takahashi, Y ^b,c   Kondo, N ^a  

^a GIFU UNIVERSITY   (Japan)

^b GIFU PREFECTURAL GIFU HOSPITAL   (Japan)

^c SHIZUOKA INSTITUTE OF EPILEPSY AND NEUROLOGICAL DISORDERS   (Japan)

Author keywords

Choline; MR imaging; MR spectroscopy; Myoinositol; N acetylaspartate; Tuberous sclerosis complex (TSC)

Indexed keywords

CHOLINE; CREATININE; INOSITOL; N ACETYLASPARTIC ACID; ASPARTIC ACID; CREATINE; DIAGNOSTIC AGENT; DRUG DERIVATIVE; N-ACETYLASPARTATE; PROTON; UNCLASSIFIED DRUG;

ADOLESCENT; ARTICLE; BRAIN CORTEX; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE SEVERITY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTON NUCLEAR MAGNETIC RESONANCE; STATISTICAL ANALYSIS; TUBEROUS SCLEROSIS; BRAIN LEVEL; METHODOLOGY; NONPARAMETRIC TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY; PRESCHOOL CHILD;

ADOLESCENT; ASPARTIC ACID; BRAIN CHEMISTRY; CHILD; CHILD, PRESCHOOL; CHOLINE; CREATINE; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MAGNETIC RESONANCE SPECTROSCOPY; MALE; PROTONS; STATISTICS, NONPARAMETRIC; TUBEROUS SCLEROSIS;

EID: 36649019950     PISSN: 0174304X     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2007-985368     Document Type: Article

References (15)

1. Aasly J, Silfvenius H, Aas TC, Sonnewald U, Olivecroma M, Juul R et al. Proton magnetic resonance spectroscopy of brain biopsies from patients with intractable epilepsy. Epilepsy Res 1999; 35: 211-217
2. Crino PB, Nathanson KL, Henske EP. The tuberous sclerosis complex. N Engl J Med 2006; 355: 1345-1356
3. Goodman M, Lamm SH, Engel A, Shepherd CW, Houser OW, Gomez MR. Cortical tuber count: a biomarker indicating neurologic severity of tuberous sclerosis complex. J Child Neurol 1997; 12: 85-90
4. Hyman MH, Whittemore VH. National Institutes of Health consensus conference tuberous sclerosis complex. Arch Neurol 2000; 57: 662-664
5. 1H-MR spectroscopy of unidentified bright objects in a case of neurofibromatosis type 1. Brain Dev 2005; 27: 595-597
6. Jones AC, Daniells CE, Snell RG, Tachataki M, Idziaszczyk SA, Krawczak M et al. Molecular genetic and phenotypic analysis reveals differences between TSC1 and TSC2 associated familial and sporadic tuberous sclerosis. Hum Mol Genet 1997; 6: 2155-2161
7. Kendall BE, Demaerel P. Imaging of pediatric and congenital brain disease. Current Opinion in Radiology 1992; 4: 28-37
8. Li LM, Cendes F, Bastos C, Andermann F, Dubeau F, Arnold DL. Neuronal metabolic dysfunction in patients with cortical development malformations. A proton magnetic resonance spectroscopic imaging study. Neurology 1998; 50: 755-759
9. Mizuno S, Takahashi Y, Kato Z, Goto H, Kondo N, Hoshi H. Magnetic resonance spectroscopy of tubers in patients with tuberous sclerosis. Acta Neurol Scand 2000; 102: 175-178
10. Mukonoweshuro W, Wilkinson ID, Griffiths PD. Proton MR Spectroscopy of cortical tubers in adults with tuberous sclerosis complex. Am J Neuroradiol 2001; 22: 1920-1925
11. Nabboutt R, Santos M, Roland Y, Delalande O, Durac O, Chiron C. Early diagnosis of subependymal giant cell astrocytoma in children with tuberous sclerosis. J Neurol Neurosurg Psychiatry 1999; 66: 370-375
12. Norfay JF, Darling C, Byrd S, Ross BD, Schwalm C, Miller R et al. Short TE proton MRS and neurofibromatosis type 1 intracranial lesion. J Comput Asssit Tomo 1999; 23: 994-1003
13. Sener RN. Infantile tuberous sclerosis change in the brain: proton MR spectroscopy findings. Comut Med Imag Graph 2000; 24: 19-24
14. Sharma MS, Suri A, Shah T, Ralte A, Sarkar C, Gupta V et al. Intraventricular glioneuronal hamartama: histopathological correlation with magnetic resonance spectroscopy. J Neuro-Oncology 2005; 74: 325-328
15. Tarasów E, Kubas B, Walecki J. MR proton spectroscopy in patients with CNS involvement in Bourneville's disease. Med Sci Monit 2001; 4: 762-765