Anticonvulsant treatment with zonisamide added to topiramate. A preliminary treatment analysis in 19 patients;Antikonvulsive komedikation von topiramat und zonisamid. Eine erste analyse der verträglichkeit bei 19 patienten

Nervenarzt

Volumn 78, Issue 12, 2007, Pages 1425-1429

  Bos M ^a   Bauer, J ^a  

^a UNIVERSITY HOSPITAL BONN   (Germany)

Author keywords

Antiepileptic drugs; Epilepsy; Pharmacotherapy; Topiramate; Zonisamide

Indexed keywords

ANTICONVULSIVE AGENT; CARBAMAZEPINE; CLOBAZAM; ETHOSUXIMIDE; FELBAMATE; LAMOTRIGINE; OXCARBAZEPINE; PHENOBARBITAL; PHENYTOIN; PREGABALIN; TOPIRAMATE; ZONISAMIDE;

ADD ON THERAPY; ADULT; ARTICLE; CLINICAL ARTICLE; CLINICAL EVALUATION; COGNITIVE DEFECT; DIARRHEA; DRUG THERAPY; DRUG WITHDRAWAL; FEMALE; FOCAL EPILEPSY; FOLLOW UP; HUMAN; MALE; SEIZURE SUSCEPTIBILITY; SIDE EFFECT; STOMACH PAIN; WEIGHT REDUCTION;

ADULT; AGED; ANTICONVULSANTS; CHILD; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; FRUCTOSE; HUMANS; ISOXAZOLES; MALE; MIDDLE AGED; PILOT PROJECTS; TREATMENT OUTCOME;

EID: 36649017096     PISSN: 00282804     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00115-007-2333-x     Document Type: Article

References (6)

1. Bauer J, Schwalen S (2000) Topiramat (Topamax). Pharmakologische Charakteristik und Stellenwert in der aktuellen Epilepsietherapie. Nervenarzt 71: 495-501
2. Brodie MJ, Duncan R, Vespignani H et al. (2005) Dose-dependent safety and efficacy of Zonisamide: A randomized, double-blind, placebo-controlled study in patients with refractory partial seizures. Epilepsia 46: 31-41
3. Fachinformation Zonegran 25 mg/ 50 mg/ 100 mg, Eisai, Frankfurt, April 2005
4. Kockelman E, Elger CE, Helmstaedter C (2003) Significant improvement in frontal lobe associated neurosychological functions after withdrawal of topiramate in epilepsy patients. Epilepsy Res 54: 171-178
5. Ohtahara S, Yamatogi Y (2007) Erratum to.,safety of zonisamide therapy: Prospective follow-up survey". Seizure 16: 87-93
6. Sackellares JC, Ramsay RE, Wilder JB et al. (2004) Randomized, controlled clinical trial of zonisamide as adjunctive treatment for refractory partial seizures. Epilepsia 45: 610-617