Ammonium 5-bromo-7-fluorobenzo-2-oxa-1,3-diazole-4-sulphonate: A new fluorogenic reagent for the determination of aminothiols by HPLC [6]

Clinical Chemistry

Volumn 53, Issue 12, 2007, Pages 2221-2222

  Cevasco, Giorgio ^a,b   Mumot, Anna Maria ^a   Scapolla, Carlo ^a   Thea, Sergio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b CNR   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOTHIOL; AMMONIUM 5 BROMO 7 FLUOROBENZO 2 OXA 1,3 DIAZOLE 4 SULPHONATE; AMMONIUM DERIVATIVE; BIOLOGICAL MARKER; REAGENT; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; CHEMICAL ANALYSIS; CHEMICAL REACTION; CHEMICAL REACTION KINETICS; CHEMICAL STRUCTURE; DERIVATIZATION; HEATING; LETTER; OXIDATION; REACTION TIME; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SIGNAL NOISE RATIO; SYNTHESIS; TEMPERATURE SENSITIVITY; ULTRAVIOLET SPECTROSCOPY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; DIPEPTIDES; FLUORESCENT DYES; FLUOROMETRY; GLUTATHIONE; HOMOCYSTEINE; HUMANS; OXADIAZOLES; SULFHYDRYL COMPOUNDS; SULFONIC ACIDS;

EID: 36649002255     PISSN: 00099147     EISSN: None     Source Type: Journal    
DOI: 10.1373/clinchem.2007.095406     Document Type: Letter

References (5)

1. Mangoni AA, Jackson SHD. Homocysteine and cardiovascular disease: current evidence and future prospects. Am J Med 2002;112:555-64.
2. Ducros V, Demuth K, Sauvant MP, Quillard M, Caussé E, Candito M, et al. Methods for homocysteine analysis and biological relevance of the results. J Chromatogr B 2002;781:207-26.
3. Imai K, Toyo'oka T, Watanabe Y. A novel fluorogenic reagent for thiols: ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulfonate. Anal Biochem 1983;128:471-3.
4. Okabe K, Wada R, Ohno K, Uchiyama S, Santa T, Imai K. Development of hydrophilic fluorogenic derivatization reagents for thiols: 4-(N-acetyl- aminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole and 4-(N- trichloroacetylaminosulfonyl)-7-fluoro-2,1,3-benzoxadiazole. J. Chromatogr A 2002;982:111-8.
5. Krijt J, Vackova M, Kozich V. Measurement of homocysteine and other aminothiols in plasma: advantages of using tris(2-carboxyethyl)phosphine as reductant compared with tri-n-butylphosphine. Clin Chem 2001;47:1821-8.