Thermal neutron irradiation field design for boron neutron capture therapy of human explanted liver

Medical Physics

Volumn 34, Issue 12, 2007, Pages 4700-4705

  Bortolussi, S ^a   Altieri, S ^a  

^a UNIVERSITY OF PAVIA   (Italy)

Author keywords

BNCT; Liver irradiation; MCNP; Thermal neutrons

Indexed keywords

BORON; NEUTRONS; PHANTOMS; REACTOR CORES; TUMORS;

BNCT; BORON NEUTRON CAPTURE THERAPY; DOSE-VOLUME HISTOGRAMS; FLUX DISTRIBUTIONS; MCNP; MONTE CARLO N PARTICLES; THERMAL NEUTRONS; THERMAL-NEUTRON FLUX;

NEUTRON IRRADIATION;

BORON;

ARTICLE; CANCER INVASION; CANCER RADIOTHERAPY; COLON ADENOCARCINOMA; CONTROLLED STUDY; EXPLANT; HUMAN; HUMAN TISSUE; LIVER GRAFT; LIVER METASTASIS; MONTE CARLO METHOD; NEUTRON CAPTURE THERAPY; NEUTRON RADIATION; PRIORITY JOURNAL; RADIATION DOSE DISTRIBUTION;

EID: 36649001790     PISSN: 00942405     EISSN: None     Source Type: Journal    
DOI: 10.1118/1.2795831     Document Type: Article

References (19)

1. J. A. Coderre and G. M. Morris, " The radiation biology of boron neutron capture therapy., " Radiat. Res. 151, 1-18 (1999). 0033-7587
2. L. E. Farr, W. H. Sweet, J. S. Robertson, S. G. Foster, H. B. Locksley, D. L. Sutherland, M. L. Mendelsohn, and E. E. Stickey, " Neutron capture therapy with boron in the treatment of glioblastoma multiforme., " AJR, Am. J. Roentgenol. 71, 279-291 (1954). 0361-803X
3. W. H. Sweet, in Workshop of Neutron Capture Therapy, Report BNL-51994, edited by, R. G. Fairchild, and, V. P. Bond, (Brookhaven National Laboratory, Upton, NY, 1986), pp. 173-177.
4. H. Hatanaka, " Clinical results of boron neutron capture therapy., " Basic Life Sci. 54, 15-21 (1990). 0090-5542
5. H. Hatanaka and Y. Nakagawa, " Clinical results of long-surviving brain tumour patients who underwent boron neutron capture therapy., " Int. J. Radiat. Oncol. Biol. Phys. 28, 1061-1066 (1994). 0360-3016
6. A. D. Chanana, " Boron neutron capture therapy for glioblastoma multiforme: Interim results from the phase I/II dose-escalation studies., " Neurosurgery 44, 1182-1193 (1999). 0148-396X
7. H. Madoc-Jones, R. Zamenhof, G. Solares, O. Harling, C. -S. Yam, K. Riley, S. Kiger, D. Wazer, G. Rogers, and M. Atkins, in Cancer Neutron Capture Therapy, edited by, Y. Mishima, (Plenum, New York, 1996).
8. P. M. Busse, O. K. Harling, M. R. Palmer, W. S. Kiger, J. Kaplan, I. Kaplan, C. Chuang, J. Y. Goorley, K. Riley, and T. H. Newton, G. A. Santa Cruz, X. -Q. Lu, and R. G. Zamenhof, " A critical examination of the results from the Harward-MIT NCT program phase I clinical trial on neutron capture therapy for intracranial disease., " J. Neurooncol. 62, 111-121 (2003). 0167-594X
9. T. Pinelli, S. Altieri, F. Fossati, A. Zonta, C. Ferrari, U. Prati, L. Roveda, S. Ngnitejeu Tata, S. Barni, P. Chiari, R. Nano, and D. M. Ferguson, in Frontiers in Neutron Capture Therapy, edited by, M. F. Hawthorne,, (Kluwer Academic, New York, 2001), Vol. II, pp. 1427-1440.
10. T. Pinelli, " TAORMINA: From the first idea to the application to the human live. r," in Proceedings: Research and Development in Neutron Capture Therapy, Essen, September 2002, edited by, W. Sauerwein,,, R. L. Moss,, and, A. Wittig, (Monduzzi, Bologna, 2002).
11. A. Zonta, " Clinical lessons from the first applications of BNCT on unresectable liver metastases., " J. Phys.: Conf. Series 41, 484-495 (2006).
12. MCNP: A General Monte Carlo N -Particle Transport Code, Version 4c, edited by, J. F. Briesmeister,, LA-13709-M, April 2000.
13. AA.VV., Rapporto finale di sicurezza del reattore Triga Mark II, Pavia, 1964.
14. AA.VV., Technical Foundation of Triga General Atomics, San Diego, 1958.
15. B. E. Watt, " Energy spectrum of neutrons from thermal fissions of U 235., " Phys. Rev. 1037, 87 (1952). 0031-899X
16. K. H. Beckurts and K. Wirtz, Neutron Physics (Springer-Verlag, Berlin, 1964).
17. ICRU Report 46, Photon Electron, Proton and Neutron Interaction Data for Body Tissues, International Commission on Radiation Units and Measurements, Bethesda, MD, 1992.
18. C. H. Westcott, " Effective cross section values of well moderated thermal reactor spectra., " Report AECL nr 1101, 1960.
19. C. H. Westcott, W. H. Walker, and T. K. Alexander, " Effective cross section and cadmium ratios for the neutron spectra of thermal reactors., " in Proceedings of the International Conference on the Peaceful Uses of Atomic Energy, Geneva, 1958 (United Nation, New York, 1959), P/202 70.