Identification of fasting-induced genes in the rat hypothalamus: Relationship with neuroprotection

Annals of the New York Academy of Sciences

Volumn 1119, Issue 1, 2007, Pages 216-226

  Chiba, Takuya ^a   Fujita, Satoshi ^a   Kubota, Haruaki ^a   Inoue, Daisuke ^a   Mizuno, Aya ^a   Komatsu, Toshimitsu ^a   Yamaza, Haruyoshi ^a   Higami, Yoshikazu ^a   Shimokawa, Isao ^a  

^a NAGASAKI UNIVERSITY GRADUATE SCHOOL OF BIOMEDICAL SCIENCES   (Japan)

Author keywords

Neurodegeneration; Oxidative stress; Suppression subtractive hybridization

Indexed keywords

COMPLEMENTARY DNA; EXCITATORY AMINO ACID TRANSPORTER 3; UBIQUITIN CONJUGATING ENZYME;

ANIMAL EXPERIMENT; ANIMAL TISSUE; CAMP DEPENDENT PROTEIN KINASE C BETA SUBUNIT GENE; CONFERENCE PAPER; CONTROLLED STUDY; DATA ANALYSIS; DIET RESTRICTION; EXCITATORY AMINO ACID CARRIER 1 GENE; FERRITIN HEAVY POLYPEPTIDE 1 GENE; GENE; GENE EXPRESSION; HYPOTHALAMUS; HYPOXIA; ISCHEMIA; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION; SUPPRESSION SUBTRACTIVE HYBRIDIZATION; UBIQUITIN CONJUGATING ENZYME E2D 3 GENE; UPREGULATION; WESTERN BLOTTING;

RATTUS;

EID: 36549034330     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1196/annals.1404.013     Document Type: Conference Paper

References (46)

1. SHEPHERD, G.M. 1994. Neurobiology, 3rd ed. Oxford University Press. New York, NY.
2. ANSON, R.M. et al. 2003. Intermittent fasting dissociates beneficial effects of dietary restriction on glucose metabolism and neuronal resistance to injury from calorie intake. Proc. Natl. Acad. Sci. USA 100: 6216-6220.
3. MATTSON, M.P. 2005. Energy intake, meal frequency, and health: a neurobiological perspective. Annu. Rev. Nutr. 25: 237-260.
4. BARZILAI, N. & G. GUPTA. 1999. Revisiting the role of fat mass in the life extension induced by caloric restriction. J. Gerontol. A Biol. Sci. Med. Sci. 54: B89-96; discussion B97-98.
5. CHIBA, T. et al. 2002. Anti-aging effects of caloric restriction: involvement of neuroendocrine adaptation by peripheral signaling. Microsc. Res. Tech. 59: 317-324.
6. KATIC, M. & C.R. KAHN. 2005. The role of insulin and IGF-1 signaling in longevity. Cell Mol. Life Sci. 62: 320-343.
7. SHIMOKAWA, I. & Y. HIGAMI. 1999. A role for leptin in the antiaging action of dietary restriction: a hypothesis. Aging (Milano) 11: 380-382.
8. SHIMOKAWA, I. & Y. HIGAMI. 2001. A role for suppression of growth hormone in the anti-aging action of caloric restriction. Gerontology 47: 582.
9. CORTON, J.C. et al. 2004. Mimetics of caloric restriction include agonists of lipid-activated nuclear receptors. J. Biol. Chem. 279: 46204-46212.
10. DIATCHENKO, L. et al. 1996. Suppression subtractive hybridization: a method for generating differentially regulated or tissue-specific cDNA probes and libraries. Proc. Natl. Acad. Sci. USA 93: 6025-6030.
11. PALKOVITS, M., BROWNSTEIN, M.,1983. Maps and Guide to Microdissection of the Rat Brain. Elsevier. New York, NY.
12. KOMATSU, T. et al. 2006. Effect of leptin on hypothalamic gene expression in calorie-restricted rats. J. Gerontol. A Biol. Sci. Med. Sci. 61: 890-898.
13. CHIBA, T. et al. 2007. Identification of differentially expressed genes in senescence-accelerated mouse testes by suppression subtractive hybridization analysis. Mamm. Genome. 18: 105-112.
14. FINN, P.F. & J.F. DICE. 2006. Proteolytic and lipolytic responses to starvation. Nutrition 22: 830-844.
15. HARA, T. et al. 2006. Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice. Nature 441: 885-889.
16. KOMATSU, M. et al. 2007. Constitutive autophagy: vital role in clearance of unfavorable proteins in neurons. Cell Death Differ. 14: 887-894.
17. KOMATSU, M. et al. 2006. Loss of autophagy in the central nervous system causes neurodegeneration in mice. Nature 441: 880-884.
18. BRZOVIC, P.S. et al. 2003. Binding and recognition in the assembly of an active BRCA1/BARD1 ubiquitin-ligase complex. Proc. Natl. Acad. Sci. USA 100: 5646-5651.
19. BRZOVIC, P.S. et al. 2006. A UbcH5/ubiquitin noncovalent complex is required for processive BRCA1-directed ubiquitination. Mol. Cell 21: 873-880.
20. HONDA, Y. et al. 2002. Cooperation of HECT-domain ubiquitin ligase hHYD and DNA topoisomerase II-binding protein for DNA damage response. J. Biol. Chem. 277: 3599-3605.
21. POLANOWSKA, J. et al. 2006. A conserved pathway to activate BRCA1-dependent ubiquitylation at DNA damage sites. Embo J. 25: 2178-2188.
22. FUKUYAMA, K. et al. 2001. Apoptosis induced by ischemia-reperfusion and fasting in gastric mucosa compared to small intestinal mucosa in rats. Dig. Dis. Sci. 46: 545-549.
23. IWAKIRI, R. et al. 2001. Programmed cell death in rat intestine: effect of feeding and fasting. Scand. J. Gastroenterol. 36: 39-47.
24. STABEL, S. & P.J. PARKER. 1991. Protein kinase C. Pharmacol. Ther. 51: 71-95.
25. STACHOWIAK, M.K. et al. 1990. Stimulation of adrenal medullary cells in vivo and in vitro induces expression of c-fos proto-oncogene. Oncogene 5: 69-73.
26. AMEMIYA, T. et al. 2005. Role of protein kinase C beta in phorbol ester-induced cfos gene expression in neurons of normotensive and spontaneously hypertensive rat brains. Brain Res. 1040: 129-136.
27. KUBO, T. & Y. HAGIWARA. 2005. Protein kinase C activation-induced increases of neural activity are enhanced in the hypothalamus of spontaneously hypertensive rats. Brain Res. 1033: 157-163.
28. STANDAERT, M.L. et al. 1999. Effects of knockout of the protein kinase C beta gene on glucose transport and glucose homeostasis. Endocrinology 140: 4470-4477.
29. BRIGHT, R. & D. MOCHLY-ROSEN. 2005. The role of protein kinase C in cerebral ischemic and reperfusion injury. Stroke 36: 2781-2790.
30. DANBOLT, N.C. 2001. Glutamate uptake. Prog. Neurobiol. 65: 1-105.
31. NIEOULLON, A. et al. 2006. The neuronal excitatory amino acid transporter EAAC1/EAAT3: does it represent a major actor at the brain excitatory synapse? J. Neurochem. 98: 1007-1018.
32. SHASHIDHARAN, P. et al. 1997. Immunohistochemical localization of the neuronspecific glutamate transporter EAAC1 (EAAT3) in rat brain and spinal cord revealed by a novel monoclonal antibody. Brain Res. 773: 139-148.
33. BALCAR, V.J., J. BORG & P. MANDEL. 1977. High affinity uptake of L-glutamate and L-aspartate by glial cells. J. Neurochem. 28: 87-93.
34. CHOI, D.W. 1988. Glutamate neurotoxicity and diseases of the nervous system. Neuron 1: 623-634.
35. REGAN, R.F.& D.W. CHOI. 1991. Glutamate neurotoxicity in spinal cord cell culture. Neuroscience 43: 585-591.
36. AOYAMA, K. et al. 2006. Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat. Neurosci. 9: 119-126.
37. SEPKUTY, J.P. et al. 2002. A neuronal glutamate transporter contributes to neurotransmitter GABA synthesis and epilepsy. J. Neurosci. 22: 6372-6379.
38. BOUGH, K.J., P.A. SCHWARTZKROIN & J.M. RHO. 2003. Calorie restriction and ketogenic diet diminish neuronal excitability in rat dentate gyrus in vivo. Epilepsia 44: 752-760.
39. HUFFMAN, J.& E.H. KOSSOFF. 2006. State of the ketogenic diet(s) in epilepsy. Curr. Neurol. Neurosci. Rep. 6: 332-340.
40. YUDKOFF, M. et al. 2006. Short-term fasting, seizure control and brain amino acid metabolism. Neurochem. Int. 48: 650-656.
41. THEIL, E.C. 1990. Ferritin mRNA translation, structure, and gene transcription during development of animals and plants. Enzyme 44: 68-82.
42. CONNOR, J.R. et al. 1995. A quantitative analysis of isoferritins in select regions of aged, parkinsonian, and Alzheimer's diseased brains. J. Neurochem. 65: 717-724.
43. WHITNALL, M. & D.R. RICHARDSON. 2006. Iron: a new target for pharmacological intervention in neurodegenerative diseases. Semin Pediatr. Neurol. 13: 186-197.
44. THOMPSON, K. et al. 2003. Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. J. Neurosci. Res. 71: 46-63.
45. NOE, V. et al. 2004. Epicatechin and a cocoa polyphenolic extract modulate gene expression in human Caco-2 cells. J. Nutr. 134: 2509-2516.
46. MANDEL, S. et al. 2006. Green tea catechins as brain-permeable, natural iron chelators-antioxidants for the treatment of neurodegenerative disorders. Mol. Nutr. Food Res. 50: 229-234.