메뉴 건너뛰기




Volumn 20, Issue 1, 2008, Pages 19-24

Novel chemotherapy options for advanced thyroid tumors: Small molecules offer great hope

Author keywords

Angiogenesis inhibitors; Novel treatments; Thyroid cancer; Tyrosine kinase inhibitors

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; AXITINIB; BEVACIZUMAB; CARBOPLATIN; CELECOXIB; CISPLATIN; COMBRESTATIN A4 PHOSPHATE; DOXORUBICIN; GEFITINIB; N (3,3 DIMETHYL 6 INDOLINYL) 2 (4 PYRIDINYLMETHYLAMINO)NICOTINAMIDE; PACLITAXEL; RETINOIC ACID; SORAFENIB; UNCLASSIFIED DRUG; VANDETANIB;

EID: 36549015772     PISSN: 10408746     EISSN: None     Source Type: Journal    
DOI: 10.1097/CCO.0b013e3282f28373     Document Type: Review
Times cited : (36)

References (29)
  • 1
    • 33846457870 scopus 로고    scopus 로고
    • Cancer Statistics, 2007
    • Clin, An authoritative source of cancer statistics in the United States including incidence and male to female ratios
    • Jemal A, Siegel R, Ward E, et al. Cancer Statistics, 2007. CA Cancer J Clin 2007; 57:43-66. An authoritative source of cancer statistics in the United States including incidence and male to female ratios.
    • (2007) CA Cancer J
    • Jemal, A.1    Siegel, R.2    Ward, E.3
  • 2
    • 33847650900 scopus 로고    scopus 로고
    • A time trend analysis of papillary and follicular cancers as a function of tumour size: A study of data from six cancer registries in France
    • This is a good review of the changes that have been seen in the incidence of thyroid cancers over the past two decades
    • Colonna M, Guizard AV, Schvartz C, et al. A time trend analysis of papillary and follicular cancers as a function of tumour size: A study of data from six cancer registries in France (1983-2000). Eur J Can 2007; 43:891-900. This is a good review of the changes that have been seen in the incidence of thyroid cancers over the past two decades.
    • (2007) Eur J Can , vol.43 , pp. 891-900
    • Colonna, M.1    Guizard, A.V.2    Schvartz, C.3
  • 3
    • 36549045155 scopus 로고    scopus 로고
    • Cancer of the endocrine system: Section 2 thyroid tumors
    • De Vita V, Hellman S, Rosenberg S, editors, Philadelphia: Lippincott Williams and Wilkins;
    • Carling T, Udelsman R. Cancer of the endocrine system: Section 2 thyroid tumors. In: De Vita V, Hellman S, Rosenberg S, editors. Cancer principles and practice. Philadelphia: Lippincott Williams and Wilkins; 2005. pp. 1503-1521.
    • (2005) Cancer principles and practice , pp. 1503-1521
    • Carling, T.1    Udelsman, R.2
  • 4
    • 33845561938 scopus 로고    scopus 로고
    • Kebebew E, Peng M, Reiff E, et al. A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer. Surgery 2006; 140:960-966. This is one of two references evaluating a differentiating agent to improve response to radioiodine.
    • Kebebew E, Peng M, Reiff E, et al. A phase II trial of rosiglitazone in patients with thyroglobulin-positive and radioiodine-negative differentiated thyroid cancer. Surgery 2006; 140:960-966. This is one of two references evaluating a differentiating agent to improve response to radioiodine.
  • 5
    • 0025324645 scopus 로고
    • Chemotherapy and multimodality treatment in thyroid carcinoma
    • Ekman ET, Lundell G, Tennvall J, et al. Chemotherapy and multimodality treatment in thyroid carcinoma. Otolaryngol Clin North Am 1990; 23:523.
    • (1990) Otolaryngol Clin North Am , vol.23 , pp. 523
    • Ekman, E.T.1    Lundell, G.2    Tennvall, J.3
  • 6
    • 85013312416 scopus 로고
    • Tumor angiogenesis: Therapeutic implications
    • Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971; 285:1182-1186.
    • (1971) N Engl J Med , vol.285 , pp. 1182-1186
    • Folkman, J.1
  • 7
    • 4143094910 scopus 로고    scopus 로고
    • Modulating angiogenesis more vs less
    • Sivakumar B, Harry L, Paleolog E. Modulating angiogenesis more vs less. JAMA 2004; 292:972-977.
    • (2004) JAMA , vol.292 , pp. 972-977
    • Sivakumar, B.1    Harry, L.2    Paleolog, E.3
  • 8
    • 36348992207 scopus 로고    scopus 로고
    • A phase II study of axitinib (AG-013736 [AG]) in patients (pts) with advanced thyroid cancers [abstract]
    • 18S:6008
    • Cohen EE, Vokes EE, Rosen LS, et al. A phase II study of axitinib (AG-013736 [AG]) in patients (pts) with advanced thyroid cancers [abstract]. J Clin Oncol 2007; 25 (18S):6008.
    • (2007) J Clin Oncol , pp. 25
    • Cohen, E.E.1    Vokes, E.E.2    Rosen, L.S.3
  • 9
    • 36549086093 scopus 로고    scopus 로고
    • Gupta V, Puttaswamy K, Lassoued W, et al. Sorafenib targets BRAF and VEGFR in metastatic thyroid carcinoma [abstract]. J Clin Oncol 2007; 25(18S):6019.
    • Gupta V, Puttaswamy K, Lassoued W, et al. Sorafenib targets BRAF and VEGFR in metastatic thyroid carcinoma [abstract]. J Clin Oncol 2007; 25(18S):6019.
  • 10
    • 40549102299 scopus 로고    scopus 로고
    • Initial results from a phase II trial of motesanib diphosphate (AMG 706) in patients with differentiated thyroid cancer (DTC) [abstract]
    • 18S:6017
    • Sherman SI, Schlumberger MJ, Droz J, et al. Initial results from a phase II trial of motesanib diphosphate (AMG 706) in patients with differentiated thyroid cancer (DTC) [abstract]. J Clin Oncol 2007; 25 (18S):6017.
    • (2007) J Clin Oncol , pp. 25
    • Sherman, S.I.1    Schlumberger, M.J.2    Droz, J.3
  • 11
    • 33744961755 scopus 로고    scopus 로고
    • Phase II study of celecoxib in metastatic differentiated thyroid carcinoma
    • Mrozek E, Kloos RT, Ringel MD, et al. Phase II study of celecoxib in metastatic differentiated thyroid carcinoma. J Clin Endocrinol Metab 2006; 91:2201-2204.
    • (2006) J Clin Endocrinol Metab , vol.91 , pp. 2201-2204
    • Mrozek, E.1    Kloos, R.T.2    Ringel, M.D.3
  • 12
    • 36549067826 scopus 로고    scopus 로고
    • Pennell NA, Daniels GH, Haddad RI, et al. A phase II study of gefitinib in patients with advanced thyroid cancer [abstract]. J Clin Oncol 2007; 25(18S):6020.
    • Pennell NA, Daniels GH, Haddad RI, et al. A phase II study of gefitinib in patients with advanced thyroid cancer [abstract]. J Clin Oncol 2007; 25(18S):6020.
  • 13
    • 34247620449 scopus 로고    scopus 로고
    • Zhang Y, Jia S, Liu Y, et al. A clinical study of all-trans-retinoid-induced differentiation therapy of advanced thyroid cancer. Nucl Med Commun 2007; 28:251-255. This is the second paper on using differentiating agents this time using a well known compound in leukemia treatment.
    • Zhang Y, Jia S, Liu Y, et al. A clinical study of all-trans-retinoid-induced differentiation therapy of advanced thyroid cancer. Nucl Med Commun 2007; 28:251-255. This is the second paper on using differentiating agents this time using a well known compound in leukemia treatment.
  • 14
    • 33847217990 scopus 로고    scopus 로고
    • Technology insight: Gene therapy and its potential role in the treatment of medullary thyroid carcinoma
    • This paper makes fascinating reading but represents a treatment option that is still many years away from clinical use
    • Messina M, Robinson B. Technology insight: gene therapy and its potential role in the treatment of medullary thyroid carcinoma. Nat Clin Pract Endocrinol Metab 2007; 3:290-301. This paper makes fascinating reading but represents a treatment option that is still many years away from clinical use.
    • (2007) Nat Clin Pract Endocrinol Metab , vol.3 , pp. 290-301
    • Messina, M.1    Robinson, B.2
  • 15
    • 0037115405 scopus 로고    scopus 로고
    • ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases
    • Carlomagno F, Vitagliano D, Guida T, et al. ZD6474, an orally available inhibitor of KDR tyrosine kinase activity, efficiently blocks oncogenic RET kinases. Cancer Res 2002; 62:7284-7290.
    • (2002) Cancer Res , vol.62 , pp. 7284-7290
    • Carlomagno, F.1    Vitagliano, D.2    Guida, T.3
  • 16
    • 33846330637 scopus 로고    scopus 로고
    • Fury MG, Solit DB, Su YB, et al. A phase I trial of intermittent high-dose gefitinib and docetaxel in patients with advanced solid tumors. Cancer Chemother Pharmacol 2007; 59:467-475. Gefitinib is no longer approved for use in the United States but its activity in this study and that by Pennell et al. [12] is very encouraging and it may make a comeback in the treatment of thyroid cancer.
    • Fury MG, Solit DB, Su YB, et al. A phase I trial of intermittent high-dose gefitinib and docetaxel in patients with advanced solid tumors. Cancer Chemother Pharmacol 2007; 59:467-475. Gefitinib is no longer approved for use in the United States but its activity in this study and that by Pennell et al. [12] is very encouraging and it may make a comeback in the treatment of thyroid cancer.
  • 18
    • 33750509391 scopus 로고    scopus 로고
    • Roman S, Lin R, Sosa JA. Prognosis of medullary thyroid carcinoma: demographic, clinical and pathological predictors of survival in 1252 cases. Cancer 2006; 107:2134-2142. This population study was the largest of its kind and gave a fascinating look at stage and demographics of medullary thyroid cancer.
    • Roman S, Lin R, Sosa JA. Prognosis of medullary thyroid carcinoma: demographic, clinical and pathological predictors of survival in 1252 cases. Cancer 2006; 107:2134-2142. This population study was the largest of its kind and gave a fascinating look at stage and demographics of medullary thyroid cancer.
  • 19
    • 0020663356 scopus 로고
    • The values of calcitonin and carcinoembryonic antigen in the treatment and management of nonfamilial thyroid carcinoma
    • Rougier P, Calmettes C, La Planche A, et al. The values of calcitonin and carcinoembryonic antigen in the treatment and management of nonfamilial thyroid carcinoma. Cancer 1983; 51:855-862.
    • (1983) Cancer , vol.51 , pp. 855-862
    • Rougier, P.1    Calmettes, C.2    La Planche, A.3
  • 20
    • 0021255199 scopus 로고
    • Diagnostic and prognostic values of carcinoembryonic antigen in medullary carcinoma of the thyroid
    • Saad MF, Fritsche HA Jr, Samaan NA. Diagnostic and prognostic values of carcinoembryonic antigen in medullary carcinoma of the thyroid. J Clin Endocrin Metab 1984; 58:889-894.
    • (1984) J Clin Endocrin Metab , vol.58 , pp. 889-894
    • Saad, M.F.1    Fritsche Jr, H.A.2    Samaan, N.A.3
  • 21
    • 4644256817 scopus 로고    scopus 로고
    • The relationship between specific RET protooncogene mutations and disease phenotype in multiple endocrine neoplasia type 2: International RET Mutation Consortium analysis
    • Eng C, Clayton D, Schuffenecker I, et al. The relationship between specific RET protooncogene mutations and disease phenotype in multiple endocrine neoplasia type 2: International RET Mutation Consortium analysis. JAMA 1996; 276:1575-1579.
    • (1996) JAMA , vol.276 , pp. 1575-1579
    • Eng, C.1    Clayton, D.2    Schuffenecker, I.3
  • 22
    • 0032894774 scopus 로고    scopus 로고
    • RET proto-oncogene in the development of human cancer
    • Eng C. RET proto-oncogene in the development of human cancer. J Clin Oncol 1999; 17:380-393.
    • (1999) J Clin Oncol , vol.17 , pp. 380-393
    • Eng, C.1
  • 23
    • 0037102369 scopus 로고    scopus 로고
    • ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis and tumor growth following oral administration
    • Wedge S, Ogilvie DJ, Dukes M, et al. ZD6474 inhibits vascular endothelial growth factor signaling, angiogenesis and tumor growth following oral administration. Cancer Res 2002; 62:4645-4655.
    • (2002) Cancer Res , vol.62 , pp. 4645-4655
    • Wedge, S.1    Ogilvie, D.J.2    Dukes, M.3
  • 24
    • 33846850223 scopus 로고    scopus 로고
    • Vandetanib (ZD6474): An orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis
    • This is a good basic science review of the mechanism of action of vandetanib
    • Herbst R, Heymach J, O'Reilly M, et al. Vandetanib (ZD6474): an orally available receptor tyrosine kinase inhibitor that selectively targets pathways critical for tumor growth and angiogenesis. Expert Opin Investig Drugs 2007; 16:239-249. This is a good basic science review of the mechanism of action of vandetanib.
    • (2007) Expert Opin Investig Drugs , vol.16 , pp. 239-249
    • Herbst, R.1    Heymach, J.2    O'Reilly, M.3
  • 25
    • 40849118632 scopus 로고    scopus 로고
    • Vandetanib in metastatic hereditary medullary thyroid cancer: Follow-up results of an open-label phase II trial [abstract]
    • 18S:6018
    • Wells SA, Gosnell JE, Gagel RF, et al. Vandetanib in metastatic hereditary medullary thyroid cancer: Follow-up results of an open-label phase II trial [abstract]. J Clin Oncol 2007; 25 (18S):6018.
    • (2007) J Clin Oncol , pp. 25
    • Wells, S.A.1    Gosnell, J.E.2    Gagel, R.F.3
  • 26
    • 36549050875 scopus 로고    scopus 로고
    • Treatment outcomes in anaplastic thyroid carcinoma from 1966-2006: Failure of overall survival enhancement despite four decades of progress in surgery, radiotherapy and chemoradiation [abstract]
    • 18S:16537
    • Chan P, Yau T, Epstein R, et al. Treatment outcomes in anaplastic thyroid carcinoma from 1966-2006: Failure of overall survival enhancement despite four decades of progress in surgery, radiotherapy and chemoradiation [abstract]. J Clin Oncol 2007; 25 (18S):16537.
    • (2007) J Clin Oncol , pp. 25
    • Chan, P.1    Yau, T.2    Epstein, R.3
  • 27
    • 33847397909 scopus 로고    scopus 로고
    • Cornett WR, Sharma AK, Day TA, et al. Anaplastic thyroid carcinoma: an overview. Curr Oncol Rep 2007; 2:152-158. This and abstracts 26 and 28 offer an excellent review of one of the deadliest cancers known in man and the relative lack of progress against it.
    • Cornett WR, Sharma AK, Day TA, et al. Anaplastic thyroid carcinoma: an overview. Curr Oncol Rep 2007; 2:152-158. This and abstracts 26 and 28 offer an excellent review of one of the deadliest cancers known in man and the relative lack of progress against it.
  • 28
    • 34247577159 scopus 로고    scopus 로고
    • Brignardello E, Gallo M, Balde I, et al. Anaplastic thyroid carcinoma: clinical outcome of 30 consecutive patients referred to a single institution in the past 5 years. E J Endo 2007; 156:425-430. Another very good review of anaplastic thyroid cancer but with a shorter period of study than reference 26.
    • Brignardello E, Gallo M, Balde I, et al. Anaplastic thyroid carcinoma: clinical outcome of 30 consecutive patients referred to a single institution in the past 5 years. E J Endo 2007; 156:425-430. Another very good review of anaplastic thyroid cancer but with a shorter period of study than reference 26.
  • 29
    • 33750299899 scopus 로고    scopus 로고
    • Phase II study of combretastatin A4 phosphate (CA4P) in patients with advanced anaplastic thyroid carcinoma [abstract]
    • 18S:5580
    • Cooney MM, Savvides P, Agarwala SS, et al. Phase II study of combretastatin A4 phosphate (CA4P) in patients with advanced anaplastic thyroid carcinoma [abstract]. J Clin Oncol 2006; 24 (18S):5580.
    • (2006) J Clin Oncol , pp. 24
    • Cooney, M.M.1    Savvides, P.2    Agarwala, S.S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.