Apneic preterms and methylxanthines: Arousal deficits, sleep fragmentation and suppressed spontaneous movements

Journal of Perinatology

Volumn 27, Issue 12, 2007, Pages 782-789

  Hayes, M J ^a,b,c   Akilesh, M R ^c   Fukumizu, M ^a,b,d   Gilles, A A ^a,b   Sallinen, B A ^a   Troese, M ^a,b   Paul, J A ^a,b  

^a UNIVERSITY OF MAINE   (United States)

^b Maine Institute for Human Genetics & Health   (United States)

^c EASTERN MAINE MEDICAL CENTER   (United States)

^d NATIONAL INSTITUTE OF NEUROSCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; CAFFEINE; METHYLXANTHINE DERIVATIVE; THEOPHYLLINE;

ACTIMETRY; AROUSAL; ARTICLE; BODY MOVEMENT; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EXPOSURE; EXTUBATION; FEMALE; HUMAN; INFANT; LONG TERM CARE; MALE; MOTOR SYSTEM; NERVE STIMULATION; NEWBORN; NEWBORN APNEA; PATIENT MONITORING; PIEZOELECTRICITY; PREDICTION; RISK REDUCTION; SLEEP AROUSAL DISORDER; SLEEP DEPRIVATION; SLEEP PATTERN; SLEEP TIME; SLEEP WAKING CYCLE; TREATMENT DURATION; WAKEFULNESS;

APNEA; AROUSAL; CASE-CONTROL STUDIES; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; MALE; MOVEMENT; RESPIRATORY SYSTEM AGENTS; SLEEP DEPRIVATION; XANTHINES;

EID: 36549003169     PISSN: 07438346     EISSN: 14765543     Source Type: Journal    
DOI: 10.1038/sj.jp.7211820     Document Type: Article

References (26)

1. Aranda JV, Turmen T. Methylxanthines in apnea of prematurity. Clin Perinatol 1979; 6: 87-108.
2. Kato I, Franco P, Groswasser J, Kelmanson I, Togari H, Kahn A. Frequency of obstructive and mixed sleep apneas in 1023 infants. Sleep 2000; 23: 487-492.
3. Harris MC, Baumgart S, Rooklin AR, Fox WW. Successful extubation in infants with respiratory distress syndrome using aminophylline. J Pediatr 1983; 103: 303-306.
4. Scannion J, Chin K, Morgan M, Durbin G, Hale K, Brown S. Caffeine or theophylline for neonatal apnoea? Arch Dis Child 1992; 67: 425-428.
5. Romagnoli C, De Carolis MP, Muzii U, Zecca E, Tortorolo G, Chiarotti M et al. Effectiveness and side effects of two different doses of caffeine in preventing apnea in premature infants. Ther Drug Monit 1992; 14: 14-19.
6. Steer PA, Henderson-Smart DJ. Caffeine versus theophylline for apnea in preterm infant. Cochrane Database Syst Rev 2000; 2: CDO0273.
7. Carnielli VP, Verlato G, Benini F, Rossi K, Cavedagni M, Filippone M, Baraldi E, Zacchello F. Metabolic and respiratory effects of theophylline in the preterm infant. Arch Dis Child 2000; 89: 39-43.
8. Mayer CA, Haxhiu MA, Martin RJ, Wilson CG. Adenosine A2A receptors mediate GABAergic inhibition of respiration in immature rats. Appl Physiol 2006; 100: 91-97.
9. Holditch-Davis D, Scher M, Schwartz T, Hudson-Barr D. Sleeping and waking state development in preterm infants. Early Hum Dev 2004; 80: 43-64.
10. Sahni R, Schulze KF, Stefanski M, Myers MM. Methodological issues in coding sleep states in immature infants. Dev Psychobiol 1995; 28: 85-101.
11. Hayes MJ, Kumar SP, Plante L, Delivoria-Papadopoulos M. Spontaneous motility in premature infants: Features of behavioral activity and rhythmic organization. Dev Psychobiol 1995, 26: 279-291.
12. Thoman EB, Holditch-Davis D, Raye JR, Phillipps AF, Rowe JC, Denenberg VH. Theophylline affects sleep-wake state development in premature infants. Neuropediatrics 1985; 16: 13-18.
13. Curzi-Dascalova L, Aujard Y, Gaultier C, Rajguru M. Sleep organization is unaffected by caffeine in premature infants. J Pediatr 2002; 140: 766-771.
14. Chardon K, Bach V, Telliez F, Cardot V, Tourneux P, Leke A et al. Effect of caffeine on peripheral chemoreceptor activity in premature neonates. J Appl Physiol 2004; 96: 2161-2166.
15. Porkka-Heiskanen T, Strecker RE, Thakkar M, Bjorkum AA, Greene RW, McCarley RW. Adenosine: A mediator of the sleep-inducing effects of prolonged wakefulness. Science 1997; 276: 1265-1268.
16. Franco P, Seret N, Van Hees NJ, Scaillat S, Vermeulen F, Gosswasser J et al. Decreased arousals among healthy infants after short-term sleep deprivation. Padiatrid 2004; 114: 192-191.
17. Symanski ME, Hayes MJ, Akilesh MK. Pattern s of premature newboms' sleep-wake states before and after nursing interventions on the night shift. J Obstet Gynecol Neonatal Nurs 2002; 31: 305-513.
18. Myers MM, Fifer WP, Schaeffer L, Sahni R, Ohira-Kist K, Stark RI et al. Effects of sleeping position and time after feeding on the organization of sleep - wake states in prematurely born infants. Sleep 1998; 21: 343-349.
19. Prechtl HFR. Problems of behavioral studies in the newborn infant. In: Lehrman DS, Hinde RA, Shaw E (eds.). Advances in the Study of Behavior, vol. 1 Academic Press: New York, 1965; 75-98.
20. Anders T, Emde R, Parmelee A. A Manual of Standardized TerminoloV, Techniques, and Criteria for Scoring of States of Sleep and Wakefulness in Newborn Infants. UCIA Brain Information Service: Los Angeles, 1971.
21. Hayes MJ, Mitchell Hayes MJ, Mitchell D. Spontaneous movements during sleep: Temporal organization and changes with age. Dev Psychobiol 1998; 32: 13-21.
22. Giganti F, Ficca G, Cioni G, Salzarulo P. Spontaneous awakenings in preterm and term infants assessed throughout 24-h video-recordings. Early Hum Dev 20D6; 82: 435-440.
23. Landolt H, Reter JC, Tonz K, Gottselig JM, Khatami R, Buckelmuller I et al. Caffeine attenuates waking and sleep electroencephalographic markers of sleep homeostasis in humans. Neuropsychoparmacology 2004, 29: 1933-1939.
24. Kahn A, Franco P, Scaillet S, Growasser J, Dan B. Development of cardiopulmonary integration and the role of arousability from sleep. Curr Opin Pulm Med 1997; 3: 440-444.
25. Schectman VL, Harper RM, Wilson AJ, Southall DP. Sleep state organization in normal infants and victims of the sudden infant death syndrome. Pediatrics 1992; 89: 865-870.
26. Denenberg VH, Zeidner LP, Thoman EB, Kramer P, Rowe JC, Philipps AF et al. Effects of theophylline on behavioral state development in the newborn rabbit. J Pharm Exp Ther 1982; 221: 604-608.