Experimental pulmonary fat embolism induced by injection of triolein in rats

Legal Medicine

Volumn 10, Issue 1, 2008, Pages 26-30

  Inoue, Hiromasa ^a   Hanagama, Masakazu ^a   Kamiya, Munechika ^a   Shinone, Kotaro ^a   Nata, Masayuki ^a  

^a MIE UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Caudal vein; Pelvic fracture; Prognosis; Pulmonary fat embolism; Triolein

Indexed keywords

FAT; TRIOLEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CIRCULATION; CONTROLLED STUDY; DISEASE SEVERITY; EXPERIMENTAL MODEL; FAT EMBOLISM; HISTOPATHOLOGY; INJECTION; LIPID BLOOD LEVEL; LUNG EMBOLISM; MALE; MORPHOMETRICS; NONHUMAN; PELVIS FRACTURE; RAT;

ANIMALS; CEREBRUM; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBOLISM, FAT; FORENSIC PATHOLOGY; INJECTIONS, INTRAVENOUS; KIDNEY; LUNG; MALE; MICROSCOPY; PULMONARY EMBOLISM; RATS; RATS, WISTAR; SEVERITY OF ILLNESS INDEX; TRIOLEIN;

EID: 36448991178     PISSN: 13446223     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.legalmed.2007.07.001     Document Type: Article

References (18)

1. ten Duis H.J. The fat embolism syndrome. Injury 28 (1997) 77-85
2. Mellor A., and Soni N. Fat embolism. Anaesthesia 56 (2001) 145-154
3. Talbot M., and Schemitsch E.H. Fat embolism syndrome: history, definition, epidemiology. Injury 37 (2006) S3-S7
4. Taviloglu K., and Yanar H. Fat embolism syndrome. Surg Today 37 (2007) 5-8
5. Bulger E.M., Smith D.G., Maier R.V., and Jurkovich G.J. Fat embolism syndrome. A 10-year review. Arch Surg 132 (1997) 435-439
6. Brandt S.E., Zeegers W.S., and Ceelen T.L. Fatal pulmonary fat embolism after dorsal spinal fusion. Eur Spine J 7 (1998) 426-428
7. Syed M.I., Jan S., Patel N.A., Shaikh A., Marsh R.A., and Stewart R.V. Fatal fat embolism after vertebroplasty: identification of the high-risk patient. Am J Neuroradiol 27 (2006) 343-345
8. Watanabe S., Terazawa K., Matoba K., and Yamada N. An autopsy case of intraoperative death due to pulmonary fat embolism-possibly caused by release of tourniquet after multiple muscle-release and tenotomy of bilateral lower limbs. Forensic Sci Int (2006) 10.1016/j.forsciint.2006.07.015
9. Brinkmann B., Borgner M., and von Bülow M. Die Fettembolie der Lungen als Todesursache. Ätiologie, Pathogenese und Beweisführung. Z Rechtsmed 78 (1976) 255-272
10. Bunai Y., Yoshimi N., Komoyama H., Iwasa M., and Ohya I. An application of a quantitative analytical system for the grading of pulmonary fat embolisms. Forensic Sci Int 39 (1988) 263-269
11. Schulz H., and Muhle H. Respiration. In: Krinke G.J. (Ed). The Handbook of Experimental Animals: The Laboratory Rat. first ed. (2000), Academic Press, London 323-344
12. Tatsumi A. Experimental pulmonary fat embolism- an ultrastructural study of the pathogenetic process of lung edema induced by autologous fat cells. Nihon Kyobu Shikkan Gakkai Zasshi 23 (1985) 643-654 in Japanese
13. Nakata Y., and Dahms T.E. Triolein increases microvascular permeability in isolated perfused rabbit lungs: role of neutrophils. J Trauma 49 (2000) 320-326
14. Kim H.J., Lee J.H., Lee C.H., Lee S.H., Moon T.Y., Cho B.M., Kim H.K., Park B.R., and Chang K.H. Experimental cerebral fat embolism: embolic effects of triolein and oleic acid depicted by MR imaging and electron microscopy. Am J Neuroradiol 23 (2002) 1516-1523
15. McGuigan R.M., Mullenix P., Norlund L.L., Ward D., Walts M., and Azarow K. Acute lung injury using oleic acid in the laboratory rat: establishment of a working model and evidence against free radicals in the acute phase. Curr Surg 60 (2003) 412-417
16. Kim Y.W., Kim H.J., Cho B.M., Moon T.Y., and Eun C.K. The study of cerebral hemodynamics in the hyperacute stage of fat embolism induced by triolein emulsion. Am J Neuroradiol 27 (2006) 398-401
17. Inoue H., Tsuji A., Kudo K., and Ikeda N. Pulmonary fat embolism induced by exposure to high ambient temperature in rats with a fatty liver. Int J Legal Med 119 (2005) 275-279
18. Inoue H., Ikeda N., Kudo K., Tsuji A., and Nata M. Relationship between pulmonary fat embolism and core body temperature in rats with a severe fatty liver. Legal Med 8 (2006) 210-213