Acanthosis nigricans: A common finding in overweight youth

Pediatric Dermatology

Volumn 24, Issue 6, 2007, Pages 601-606

  Brickman, Wendy J ^a   Binns, Helen J ^a,b   Jovanovic, Borko D ^b   Kolesky, Scott ^c   Mancini, Anthony J ^a,b   Metzger, Boyd E ^b  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACANTHOSIS NIGRICANS; ADOLESCENT; ARTICLE; BODY MASS; DEMOGRAPHY; DIABETES MELLITUS; ETHNICITY; FAMILY HISTORY; FEMALE; GLUCOSE HOMEOSTASIS; HUMAN; MAJOR CLINICAL STUDY; MALE; OBESITY; PHOTOGRAPHY; PREGNANCY DIABETES MELLITUS; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD;

ACANTHOSIS NIGRICANS; ADOLESCENT; ADULT; AFRICAN AMERICANS; BODY MASS INDEX; CHILD; DIABETES, GESTATIONAL; FEMALE; HISPANIC AMERICANS; HUMANS; LOGISTIC MODELS; MALE; OVERWEIGHT; PREGNANCY; RISK FACTORS; SEX FACTORS; UNITED STATES; URBAN POPULATION;

EID: 36448974175     PISSN: 07368046     EISSN: 15251470     Source Type: Journal    
DOI: 10.1111/j.1525-1470.2007.00547.x     Document Type: Article

References (18)

1. Cruz P Jr., Hud J Jr. Excess insulin binding to insulin-like growth factor receptors: proposed mechanism for acanthosis nigricans. J Invest Dermatol 1992 98 (6 Suppl. 82S 85S.
2. Stuart C, Driscoll M, Lundquist K et al. Acanthosis nigricans. J Basic Clin Physiol Pharmacol 1998 9 : 407 418.
3. Dunaif A, Green G, Phelps RG et al. Acanthosis nigricans, insulin action, and hyperandrogenism: clinical, histological, and biochemical findings. J Clin Endocrinol Metab 1991 73 : 590 595.
4. Kahn CR, Flier JS, Bar RS et al. The syndromes of insulin resistance and acanthosis nigricans: insulin receptor disorders in man. N Engl J Med 1976 294 : 739 745.
5. Stuart CA, Smith MM, Gilkeson CR et al. Acanthosis nigricans among Native Americans: an indicator of high diabetes risk. Am J Public Health 1994 84 : 1839 1842.
6. Hud JA, Cohen JB, Wagner JM et al. Prevalence and significance of acanthosis nigricans in an adult obese population. Arch Dermatol 1992 128 : 941 944.
7. Stuart C, Pate C, Peters E. Prevalence of acanthosis nigricans in an unselected population. Am J Med 1989 87 : 269 272.
8. Mukhtar Q, Cleveley G, Voorhees RE et al. Prevalence of acanthosis nigricans and its association with hyperinsulinemia in New Mexico adolescents. J Adolesc Health 2001 28 : 372 376.
9. Stuart CA, Gilkison CR, Keenan BS et al. Hyperinsulinemia and acanthosis nigricans in African Americans. J Natl Med Assoc 1997 89 : 523 527.
10. Fagot-Campagna A, Pettitt DJ, Engelgau MM et al. Type 2 diabetes among North American children and adolescents: an epidemiologic review and a public health perspective. J Pediatr 2000 136 : 664 672.
11. Hedley AA, Ogden CL, Johnson CL et al. Prevalence of overweight and obesity among US children, adolescents, and adults, 1999-2002. JAMA 2004 291 : 2847 2850.
12. Goran MI, Ball GDC, Cruz ML. Obesity and risk of type 2 diabetes and cardiovascular disease in children and adolescents. J Clin Endocrinol Metab 2003 88 : 1417 1427.
13. LeBailly S, Ariza A, Bayldon B et al. The origin and evolution of a regional pediatric practice-based research network: practical and methodological lessons from the Pediatric Practice Research Group. Curr Probl Pediatr Adolesc Health Care 2003 33 : 124 134.
14. Burke JP, Hale DE, Hazuda HP et al. A quantitative scale of acanthosis nigricans. Diabetes Care 1999 22 : 1655 1659.
15. American Academy of Pediatrics, Committee on Public Education. Children, adolescents and television. Pediatrics 2001 107 : 423 426.
16. Drobac S, Brickman W, Smith T et al. Evaluation of a type 2 diabetes screening protocol in an urban pediatric clinic. Pediatrics 2004 114 : 141 148.
17. Urrutia-Rojas X, Menchaca J, Wadley W et al. Cardiovascular risk factors in Mexican-American children at risk for type 2 diabetes mellitus (T2DM). J Adolesc Health 2004 34 : 290 299.
18. Stoddart ML, Blevins KS, Lee ET et al. Association of acanthosis nigricans with hyperinsulinemia compared with other selected risk factors for type 2 diabetes in Cherokee Indians. Diabetes Care 2002 25 : 1009 1014.