-
1
-
-
85043834741
-
-
EP 208846, JP 86260083, JP 95084468, US 4626538
-
Dusza, J.P., Tomcufcik, A.S., Albright, J.D. (American Cyanamid Co.). [7-(3-Disubstd. amino)phenyl]pyrazolo[1,5-a]pyrimidines. EP 208846, JP 86260083, JP 95084468, US 4626538.
-
[7-(3-Disubstd. Amino)phenyl]pyrazolo[1,5-a]pyrimidines
-
-
Dusza, J.P.1
Tomcufcik, A.S.2
Albright, J.D.3
-
2
-
-
3643101044
-
Hypnotic effect of CL284,846, a new non-benzodiazepine
-
Abst P1-266.
-
Noguchi, H., Kitazumi, K., Sasaki, M., Suzuki, H., Shiba, T., Nishiki, K., Inomata, N. Hypnotic effect of CL284,846, a new non-benzodiazepine. Jpn J Pharmacol 1995, 67(Suppl. 1): Abst P1-266.
-
(1995)
Jpn J Pharmacol
, vol.67
, Issue.1 SUPPL.
-
-
Noguchi, H.1
Kitazumi, K.2
Sasaki, M.3
Suzuki, H.4
Shiba, T.5
Nishiki, K.6
Inomata, N.7
-
3
-
-
0000460931
-
Pharmacology of CL 284,846, a non-benzodiazepine sedative with reduced amnestic liability
-
Abst 303 4
-
Day, I.P., Clody, D.E., Monaghan, M.M., Abel, M.S., Dusza, J.P., Beer, B. Pharmacology of CL 284,846, a non-benzodiazepine sedative with reduced amnestic liability. Soc Neurosci Abst 1992, 18(Part 1). Abst 303 4.
-
(1992)
Soc Neurosci Abst
, vol.18
, Issue.1 PART
-
-
Day, I.P.1
Clody, D.E.2
Monaghan, M.M.3
Abel, M.S.4
Dusza, J.P.5
Beer, B.6
-
4
-
-
3643134295
-
Evaluation of the discriminative stimulus effects of the novel putative sedative-hypnotic CL 284,846
-
Abst 569.15
-
Vanover, K.E., Barrett, J.E. Evaluation of the discriminative stimulus effects of the novel putative sedative-hypnotic CL 284,846. Soc Neurosci Abst 1993, 19(Part 2): Abst 569.15.
-
(1993)
Soc Neurosci Abst
, vol.19
, Issue.2 PART
-
-
Vanover, K.E.1
Barrett, J.E.2
-
5
-
-
3643102059
-
Pharmacokinetics (PK) and pharmacodynamics (PD) of CL 284,846 (CL) in rats
-
Abst PPDM 8349
-
Gaudreault, J., Varin, F., Pollack, G.M. Pharmacokinetics (PK) and pharmacodynamics (PD) of CL 284,846 (CL) in rats. Pharm Res 1993, 10(10, Suppl.): Abst PPDM 8349.
-
(1993)
Pharm Res
, vol.10
, Issue.10 SUPPL.
-
-
Gaudreault, J.1
Varin, F.2
Pollack, G.M.3
-
6
-
-
3643096857
-
In vitro metabolism of CL284,846, a novel non-benzodiazepine sedative/hypnotic, in human and monkey liver preparations
-
Abst PPDM 8130
-
Wirth, M., Chaudhary, I., Cosulich, D., Nicolau, G. In vitro metabolism of CL284,846, a novel non-benzodiazepine sedative/hypnotic, in human and monkey liver preparations. Pharm Res 1993, 10(10, Suppl.): Abst PPDM 8130.
-
(1993)
Pharm Res
, vol.10
, Issue.10 SUPPL.
-
-
Wirth, M.1
Chaudhary, I.2
Cosulich, D.3
Nicolau, G.4
-
7
-
-
0001013913
-
Species comparison of in vitro and in vivo metabolism of CL 284,846, a non-benzodiazepine sedative/hypnotic agent
-
Abst PPDM 8236
-
Chaudhary, I., DeMaio, W., Kantrowitz, J. Species comparison of in vitro and in vivo metabolism of CL 284,846, a non-benzodiazepine sedative/hypnotic agent. Pharm Res 1994, 11(10, Suppl.): Abst PPDM 8236.
-
(1994)
Pharm Res
, vol.11
, Issue.10 SUPPL.
-
-
Chaudhary, I.1
DeMaio, W.2
Kantrowitz, J.3
-
8
-
-
0342643521
-
In vitro and in vivo metabolism of CL284,846, a novel non-benzodiazepine sedative/hypnotic in humans
-
Abst PPDM 8129
-
Chaudhary, I., DeMaio, W., Kelly, R.G., Morton, G., Cosulich, D., Nicolau, G. In vitro and in vivo metabolism of CL284,846, a novel non-benzodiazepine sedative/hypnotic in humans. Pharm Res 1993, 10(10, Suppl.): Abst PPDM 8129.
-
(1993)
Pharm Res
, vol.10
, Issue.10 SUPPL.
-
-
Chaudhary, I.1
DeMaio, W.2
Kelly, R.G.3
Morton, G.4
Cosulich, D.5
Nicolau, G.6
-
9
-
-
3643067739
-
Pharmacokinetics of CL 284,846 after multiple oral doses to dogs and rats
-
Abst 209
-
Woolcock, I.M., Doepner, D., Milisci, M., Amorusi, P., Wolford, S., Tham, P., Halperin-Walega, E. Pharmacokinetics of CL 284,846 after multiple oral doses to dogs and rats. Pharmacologist 1991, 33(3): Abst 209.
-
(1991)
Pharmacologist
, vol.33
, Issue.3
-
-
Woolcock, I.M.1
Doepner, D.2
Milisci, M.3
Amorusi, P.4
Wolford, S.5
Tham, P.6
Halperin-Walega, E.7
-
10
-
-
0027986537
-
CL 284,846, a novel sedative-hypnotic: Evaluation of its metabolites for pharmacological activity in vitro and in vivo
-
Vanover, K.E., Mangano, R.M., Barrett, J.E. CL 284,846, a novel sedative-hypnotic: Evaluation of its metabolites for pharmacological activity in vitro and in vivo. Drug Develop Res 1994, 33: 39-45.
-
(1994)
Drug Develop Res
, vol.33
, pp. 39-45
-
-
Vanover, K.E.1
Mangano, R.M.2
Barrett, J.E.3
-
11
-
-
0028271564
-
A placebo-controlled evaluation of single, escalating doses of CL 284,846, a non-benzodiazepine hypnotic
-
Beer, B., Ieni, J.R., Wu, W.-H., Clody, D., Amorusi, P., Rose, J., Mant, T., Gaudreault, J., Cato, A., Stern, W. A placebo-controlled evaluation of single, escalating doses of CL 284,846, a non-benzodiazepine hypnotic. J Clin Pharmacol 1994, 34(4): 335-44.
-
(1994)
J Clin Pharmacol
, vol.34
, Issue.4
, pp. 335-344
-
-
Beer, B.1
Ieni, J.R.2
Wu, W.-H.3
Clody, D.4
Amorusi, P.5
Rose, J.6
Mant, T.7
Gaudreault, J.8
Cato, A.9
Stern, W.10
-
12
-
-
0028939623
-
Phase I study of LJC 10,846 (L-846), a novel benzodiazepine receptor-related hypnotic - Comparative double-blind study with placebo
-
Uchiumi, M., Sugiyama, T., Suzuki, M., Murasaki, M. Phase I study of LJC 10,846 (L-846), a novel benzodiazepine receptor-related hypnotic - Comparative double-blind study with placebo. Jpn J Neuropsychopharmacol 1995, 17(3): 185-202.
-
(1995)
Jpn J Neuropsychopharmacol
, vol.17
, Issue.3
, pp. 185-202
-
-
Uchiumi, M.1
Sugiyama, T.2
Suzuki, M.3
Murasaki, M.4
-
13
-
-
3643068776
-
-
April 10, New York
-
American Home Products Corp. Analyst Presentation (April 10, New York) 1995.
-
(1995)
Analyst Presentation
-
-
-
15
-
-
0028901230
-
Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: Increases in punished responding and antagonism of the pentylenetetrazole cue
-
Sanger, D.J. Behavioural effects of novel benzodiazepine (omega) receptor agonists and partial agonists: Increases in punished responding and antagonism of the pentylenetetrazole cue. Behav Pharmacol 1995, 6: 116-26.
-
(1995)
Behav Pharmacol
, vol.6
, pp. 116-126
-
-
Sanger, D.J.1
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