Structural and thermodynamic bases for the design of pure prolactin receptor antagonists: X-ray structure of Del1-9-G129R-hPRL

Journal of Biological Chemistry

Volumn 282, Issue 45, 2007, Pages 33118-33131

  Jomain, Jean Baptiste ^a,b   Tallet, Estelle ^a,b   Broutin, Isabelle ^b   Hoos, Sylviane ^c   Van Agthoven, Jan ^a,b   Ducruix, Arnaud ^b   Kelly, Paul A ^a,b   Kragelund, Birthe B ^d   England, Patrick ^c   Goffin, Vincent ^a,b  

^a INSERM   (France)

^b UNIVERSITÉ PARIS DESCARTES   (France)

^c INSTITUT PASTEUR   (France)

^d UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

HORMONES; SURFACE PLASMON RESONANCE; THERMODYNAMIC STABILITY;

HUMAN PROLACTIN; INTRINSIC FLEXIBILITY; MUTATIONS;

BIOCHEMISTRY;

GLYCINE; MEMBRANE PROTEIN; PROLACTIN RECEPTOR; RECEPTOR BLOCKING AGENT;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING ASSAY; BIOASSAY; CELL CULTURE; CIRCULAR DICHROISM; COMPETITIVE INHIBITION; GENE DELETION; GENE MUTATION; HUMAN; NONHUMAN; PHYSICAL CHEMISTRY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SURFACE PLASMON RESONANCE; THERMODYNAMICS; X RAY CRYSTALLOGRAPHY; X RAY DIFFRACTION;

EID: 36349020704     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M704364200     Document Type: Article

References (55)

1. Goffin, V., Touraine, P., Culler, M. D., and Kelly, P. A. (2006) Nat. Clin. Pract. Endocrinol. Metab 2, 571-581
2. Goffin, V., Bernichtein, S., Touraine, P., and Kelly, P. A. (2005) Endocr. Rev. 26, 400-422
3. Clevenger, C. V., Furth, P. A., Hankinson, S. E., and Schuler, L. A. (2003) Endocr. Rev. 24, 1-27
4. Bole-Feysot, C., Goffin, V., Edery, M., Binart, N., and Kelly, P. A. (1998) Endocr. Rev. 19, 225-268
5. Bernichtein, S., Kayser, C., Dillner, K., Moulin, S., Kopchick, J. J., Martial, J. A., Norstedt, G., Isaksson, O., Kelly, P. A., and Goffin, V. (2003) J. Biol. Chem. 278, 35988-35999
6. Goffin, V., Tallet, E., Jomain, J. B., and Kelly, P. A. (2007) Recent Patents on Endocrine, Metabolic & Immune Drug Discovery 1, 41-52
7. Ma, F. Y., Anderson, G. M., Gunn, T. D., Goffin, V., Grattan, D. R., and Bunn, S. J. (2005) Endocrinology 146, 5112-5119
8. Ma, F. Y., Grattan, D. R., Goffin, V., and Bunn, S. J. (2005) Endocrinology 146, 93-102
9. Eyal, O., Jomain, J. B., Kessler, C., Goffin, V., and Handwerger, S. (2007) Biol. Reprod. 76, 777-783
10. Diogenes, A., Patwardhan, A. M., Jeske, N. A., Ruparel, N. B., Goffin, V., Akopian, A. N., and Hargreaves, K. M. (2006) J. Neurosci. 26, 8126-8136
11. Dagvadorj, A., Collins, S., Jomain, J. B., Abdulghani, J., Karras, J., Zellweger, T., Li, H., Nurmi, M., Alanen, K., Mirtti, T., Visakorpi, T., Bubendorf, L., Goffin, V., and Nevalainen, M. T. (2007) Endocrinology 148, 3089-3101
12. Goffin, V., Struman, I., Mainfroid, V., Kinet, S., and Martial, J. A. (1994) J. Biol. Chem. 269, 32598-32606
13. Goffin, V., Kinet, S., Ferrag, F., Binart, N., Martial, J. A., and Kelly, P. A. (1996) J. Biol. Chem. 271, 16573-16579
14. Kinet, S., Bernichtein, S., Kelly, P. A., Martial, J. A., and Goffin, V. (1999) J. Biol. Chem. 274, 26033-26043
15. Bernichtein, S., Jeay, S., Vaudry, R., Kelly, P. A., and Goffin, V. (2003) Endocrine 20, 177-190
16. Bernichtein, S., Jomain, J. B., Kelly, P. A., and Goffin, V. (2003) Mol. Cell. Endocrinol. 208, 11-21
17. De Vos, A. M., Ultsch, M., and Kossiakoff, A. A. (1992) Science 255, 306-312
18. Fuh, G., Cunningham, B. C., Fukunaga, R., Nagata, S., Goeddel, D. V., and Wells, J. A. (1992) Science 256, 1677-1680
19. Boutin, J. M., Edery, M., Shirota, M., Jolicoeur, C., Lesueur, L., Ali, S., Gould, D., Djiane, J., and Kelly, P. A. (1989) Mol. Endocrinol. 3, 1455-1461
20. Boutin, J. M., Jolicoeur, C., Okamura, H., Gagnon, J., Edery, M., Shirota, M., Banville, D., Dusanter-Fourt, I., Djiane, J., and Kelly, P. A. (1988) Cell 53, 69-77
21. Teilum, K., Hoch, J. C., Goffin, V., Kinet, S., Martial, J. A., and Kragelund, B. B. (2005) J. Mol. Biol. 351, 810-823
22. Paris, N., Rentier-Delrue, F., Defontaine, A., Goffin, V., Lebrun, J. J., Mercier, L., and Martial, J. A. (1990) Biotechnol. Appl. Biochem. 12, 436-449
23. Potterton, E., Briggs, P., Turkenburg, M., and Dodson, E. (2003) Acta Crystallogr. Sect. D. Biol. Crystallogr. 59, 1131-1137
24. Collaborative Computational Project, No 4 (1994) Acta Crystallogr. Sect. D Biol. Crystallogr. 50, 760-763
25. Read, R. J. (2001) Acta Crystallogr. Sect. D Biol. Crystallogr. 57, 1373-1382
26. Storoni, L. C., McCoy, A. J., and Read, R. J. (2004) Acta Crystallogr. Sect. D Biol. Crystallogr. 60, 432-438
27. McCoy, A. J., Grosse-Kunstleve, R. W., Storoni, L. C., and Read, R. J. (2005) Acta Crystallogr. Sect. D Biol. Crystallogr. 61, 458-464
28. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr. A 47, 110-119
29. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr. Sect. D Biol. Crystallogr. 53, 240-255
30. Laskowski, R. A., MacArthur, M. W., Moss, D. S., and Thornton, J. M. (1993) J. Appl. Crystallogr. 26, 283-291
31. Flores, S., Echols, N., Milburn, D., Hespenheide, B., Keating, K., Lu, J., Wells, S., Yu, E. Z., Thorpe, M., and Gerstein, M. (2006) Nucleic Acids Res. 34, D296-D301
32. Lindahl, E., Azuara, C., Koehl, P., and Delarue, M. (2006) Nucleic Acids Res. 34, W52-W56
33. Oliveberg, M., Vuilleumier, S., and Fersht, A. R. (1994) Biochemistry 33, 8826-8832
34. Willard, F. S., and Siderovski, D. P. (2006) Anal. Biochem. 353, 147-149
35. Bernichtein, S., Kinet, S., Jeay, S., Madern, M., Martial, J. A., Kelly, P. A., and Goffin, V. (2001) Endocrinology 142, 3950-3963
36. Glezer, A., Soares, C. R., Vieira, J. G., Giannella-Neto, D., Ribela, M. T., Goffin, V., and Bronstein, M. D. (2006) J. Clin. Endocrinol. Metab. 91, 1048-1055
37. Walsh, S. T., and Kossiakoff, A. A. (2006) J. Mol. Biol. 358, 773-784
38. Keeler, C., Dannies, P. S., and Hodsdon, M. E. (2003) J. Mol. Biol. 328, 1105-1121
39. Keeler, C., Jablonski, E. M., Albert, Y. B., Taylor, B. D., Myszka, D. G., Clevenger, C. V., and Hodsdon, M. E. (2007) Biochemistry 46, 2398-2410
40. Elkins, P. A., Christinger, H. W., Sandowski, Y., Sakal, E., Gertler, A., De Vos, A. M., and Kossiakoff, A. A. (2000) Nat. Struct. Biol. 7, 808-815
41. Bernat, B., Pal, G., Sun, M., and Kossiakoff, A. A. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 952-957
42. Walsh, S. T., Jevitts, L. M., Sylvester, J. E., and Kossiakoff, A. A. (2003) Protein Sci. 12, 1960-1970
43. Chen, W. Y., Wight, D. C., Mehta, B. V., Wagner, T. E., and Kopchick, J. J. (1991) Mol. Endocrinol. 5, 1845-1852
44. Helman, D., Staten, N. R., Grosclaude, J., Daniel, N., Nespoulous, C., Djiane, J., and Gertler, A. (1998) J. Biol. Chem. 273, 16067-16074
45. Kinet, S., Bernichtein, S., Llovera, M., Kelly, P. A., Martial, J. A., and Goffin, V. (2001) Recent Res. Dev. Endocrinol. 2, 1-24
46. Goffin, V., Bernichtein, S., Carrière, O., Bennett, W. F., Kopchick, J. J., and Kelly, P. A. (1999) Endocrinology 140, 3853-3856
47. Dattani, M. T., Hindmarsh, P. C., Brook, C. D., Robinson, I. F., Kopchick, J. J., and Marshall, N. J. (1995) J. Biol. Chem. 270, 9222-9226
48. Fuh, G., Colosi, P., Wood, W. I., and Wells, J. A. (1993) J. Biol. Chem. 268, 5376-5381
49. Gadd, S. L., and Clevenger, C. V. (2006) Mol. Endocrinol. 20, 2734-2746
50. Qazi, A. M., Tsai-Morris, C. H., and Dufau, M. L. (2006) Mol. Endocrinol. 20, 1912-1923
51. Sivaprasad, U., Canfield, J. M., and Brooks, C. L. (2004) Biochemistry 43, 13755-13765
52. Horn, J. R., Kraybill, B., Petro, E. J., Coales, S. J., Morrow, J. A., Hamuro, Y., and Kossiakoff, A. A. (2006) Biochemistry 45, 8488-8498
53. Kaarsholm, N. C., Norris, K., Jorgensen, R. J., Mikkelsen, J., Ludvigsen, S., Olsen, O. H., Sorensen, A. R., and Havelund, S. (1993) Biochemistry 32, 10773-10778
54. Osslund, T. D., Syed, R., Singer, E., Hsu, E. W., Nybo, R., Chen, B. L., Harvey, T., Arakawa, T., Narhi, L. O., Chirino, A., and Morris, C. F. (1998) Protein Sci. 7, 1681-1690
55. Zakrzewska, M., Krowarsch, D., Wiedlocha, A., Olsnes, S., and Otlewski, J. (2006) Biochemistry 45, 15338-15348