Cardiovirus 2A protein associates with 40S but not 80S ribosome subunits during infection

Journal of Virology

Volumn 81, Issue 23, 2007, Pages 13067-13074

  Groppo, Rachel ^a   Palmenberg, Ann C ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS PROTEIN 2A;

40S RIBOSOME SUBUNIT; 80S RIBOSOME SUBUNIT; ARTICLE; CARDIOVIRUS; CONTROLLED STUDY; ENCEPHALOMYOCARDITIS VIRUS; HELA CELL; HUMAN; HUMAN CELL; INTERNAL RIBOSOME ENTRY SITE; NONHUMAN; PICORNAVIRUS; POLYSOME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIBOSOME SUBUNIT; RNA TRANSLATION; VIRUS CELL INTERACTION;

ENCEPHALOMYOCARDITIS VIRUS; HUMANS; POLYRIBOSOMES; PROTEIN BIOSYNTHESIS; RIBOSOME SUBUNITS, SMALL, EUKARYOTIC; RIBOSOMES; VIRAL PROTEINS;

CARDIOVIRUS; ENCEPHALOMYOCARDITIS VIRUS; PICORNAVIRIDAE;

EID: 36349012532     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00185-07     Document Type: Article

References (29)

1. Aminev, A. G., S. P. Amineva, and A. C. Palmenberg. 2003. Encephalomyocarditis viral protein 2A localizes to nucleoli and inhibits cap-dependent mRNA translation. Virus Res. 95:45-57.
2. Aminev, A. G., S. P. Amineva, and A. C. Palmenberg. 2003. Encephalomyocarditis virus (EMCV) proteins 2A and 3BCD localize to nuclei and inhibit cellular mRNA transcription but not rRNA transcription. Virus Res. 95:59-73.
3. Belov, G. A., P. V. Lidsky, O. V. Mitkitas, D. Egger, K. A. Lukyanov, K. Bienz, and V. Agol. 2004. Bidirectional increase in permeability of nuclear envelope upon poliovirus infection and accompanying alterations of nuclear pores. J. Virol. 78:10166-10177.
4. Bochkov, Y., and A. C. Palmenberg. 2006. Translational efficiency of an EMCV IRES in bicistronic vectors is dependent upon IRES sequence and gene location. BioTechniques 41:238-290.
5. DeStefano, J., E. Olmsted, R. Panniers, and J. Lucas-Lenard. 1990. The alpha subunit of eucaryotic initiation factor 2 is phosphorylated in mengovirus-infected mouse L cells. J. Virol. 64:4445-4453.
6. Devaney, M. A., V. N. Vakharia, R. E. Lloyd, E. Ehrenfeld, and M. J. Grubman. 1988. Leader protein of foot-and-mouth disease virus is required for cleavage of the p220 component of the cap-binding protein complex. J. Virol. 62:4407-4409.
7. Gingras, A. C., Y. Svitkin, G. J. Belsham, A. Pause, and N. Sonenberg. 1996. Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and polio. Proc. Natl. Acad. Sci. USA 93:5578-5583.
8. Gorbalenya, A. E., K. M. Chumakov, and V. I. Agol. 1978. RNA-binding properties of nonstructural polypeptide G of encephalomyocarditis virus. Virology 88:183-185.
9. Gradi, A., Y. V. Svitkin, W. Sommergruber, H. Imataka, S. Morino, T. Skern, and N. Sonenberg. 2003. Human rhinovirus 2A proteinase cleavage sites in eukaryotic initiation factors (eIF) 4GI and eIF4GI1 are different. J. Virol. 77:5026-5029.
10. Hahn, H., and A. C. Palmenberg. 2001. Deletion mapping of the encephalomyocarditis virus 2A protein and the adjacent primary cleavage site. J. Virol. 75:7215-7218.
11. Hahn, H., and A. C. Palmenberg. 1995. Encephalomyocarditis viruses with short poly(C) tracts are more virulent than their Mengo virus counterparts. J. Virol. 69:2697-2699.
12. Hahn, H., and A. C. Palmenberg. 1996. Mutational analysis of the encephalomyocarditis virus primary cleavage. J. Virol. 70:6870-6875.
13. Jen, G., B. M. Detjen, and R. E. Thach. 1980. Shutoff of HeLa cell protein synthesis by encephalomyocarditis virus and poliovirus: a comparative study. J. Virol. 35:150-156.
14. Kolupaeva, V. G., A. Unbehaun, I. B. Lomakin, C. T. T. Hellen, and T. V. Pestova. 2005. Binding of eukaryotic initiation factor 3 to ribosomal 40S subunits and its role in ribosomal dissociation and anti-association. RNA 11:470-486.
15. Medvedkina, O. A., I. V. Scarlat, N. O. Kalinina, and V. I. Agol. 1974. Virus-specific proteins associated with ribosomes of Krebs-II cells infected with encephalomyocarditis virus. FEBS Lett. 39:4-9.
16. Molla, A., A. V. Paul, and E. Wimmer. 1991. Cell-free, de novo synthesis of poliovirus. Science 254:1647-1651.
17. Mosenkis, J., S. Daniels-McQueen, S. Janovec, R. Duncan, J. W. B. Hershey, J. A. Grifo, W. C. Merrick, and R. E. Thach. 1985. Shutoff of host translation by encephalomyocarditis virus infection does not involve cleavage of the eucaryotic initiation factor 4F polypeptide that accompanies poliovirus infection. J. Virol. 54:643-645.
18. Penman, S., K. Scherrer, Y. Becker, and J. Darnell. 1963. Polyribosomes in normal and poliovirus-infected HeLa cells and their relationship to messenger-RNA. Proc. Natl. Acad. Sci. USA 49:654-662.
19. Pensiero, M. N., and J. Lucas-Lenard. 1985. Evidence for the presence of an inhibitor on ribosomes in mouse L cells infected with mengovirus. J. Virol. 56:161-171.
20. Plagemann, P. 1968. Mengovirus replication in Novikoff rat hepatoma and mouse L cells: effects on synthesis of host-cell macromolecules and virus-specific synthesis of ribonucleic-acid. J. Virol. 2:461-472.
21. Porter, F. W., Y. Bochkov, A. J. Albee, C. Wiese, and A. C. Palmenberg. 2006. A picornavirus protein disrupts nucleocytoplasmic transport by targeting Ran GTPase. Proc. Natl. Acad. Sci. USA 103:12417-12422.
22. Qu, X., Z. Yang, S. Zhang, L. Shen, A. W. Dangel, J. H. Hughes, K. L. Redman, L. Wu, and C. Y. Yu. 1998. The human DEVH-box protein Ski2W from the HLA is localized in nucleoli and ribosomes. Nucleic Acids Res. 26:4068-1077.
23. Racaniello, V. R. 2001. Picornaviridae: the viruses and their replication, p. 685-722. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Straus (ed.), Fields virology, 4th ed. Lippincott Williams and Wilkins, Philadelphia, PA.
24. Skern, T., B. Hampolz, A. Guarne, A. Fita, E. M. Bergmann, J. Petersen, and M. N. James. 2002. Structure and function of picornavirus proteases. ASM Press, Washington, DC.
25. Stuger, R., A. C. J. Timmers, H. A. Raue, and J. van't Riet. 2000. Nuclear import of ribosomal proteins: evidence for a novel type of nucleolar localization signal, p. 205-217. In R. A. Garrett, S. R. Douthwaite, A. Liljas, A. T. Matheson, P. B. Moore, and H. F. Noller (ed.), The ribosome: structure, function, antibiotics, and cellular interactions. ASM Press, Washington, DC.
26. Svitkin, Y. V., H. Hahn, A. C. Gingras, A. C. Palmenberg, and N. Sonenberg. 1998. Rapamycin and wortmannin enhance replication of a defective encephalomyocarditis virus. J. Virol. 72:5811-5819.
27. Svitkin, Y. V., and N. Sonenberg. 2003. Cell-free synthesis of encephalomyocarditis virus. I. Virol. 77:6551-6555.
28. Taub, F., and T. C. Johnson. 1975. The mechanism of polyribosome disaggregation in brain tissue by phenylalanine. Biochem. J. 151:173-180.
29. Yalamanchili, P., U. Datta, and A. Dasgupta. 1997. Inhibition of host cell transcription by poliovirus: cleavage of transcription factor CREB by poliovirus-encoded protease 3Cpro. J. Virol. 71:1220-1226.