Mild Hyperuricemia and Subclinical Renal Damage in Untreated Primary Hypertension

American Journal of Hypertension

Volumn 20, Issue 12, 2007, Pages 1276-1282

  Viazzi, Francesca ^a   Leoncini, Giovanna ^a   Ratto, Elena ^a   Falqui, Valeria ^a   Parodi, Angelica ^a   Conti, Novella ^a   Derchi, Lorenzo E ^b   Tomolillo, Cinzia ^a   Deferrari, Giacomo ^a   Pontremoli, Roberto ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Hypertension; microalbuminuria; renal abnormalities; renal resistive index; serum uric acid

Indexed keywords

ALBUMIN; CREATININE; URIC ACID;

ADULT; ARTICLE; CREATININE CLEARANCE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; HYPERTENSION; HYPERURICEMIA; KIDNEY INJURY; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PREVALENCE; PRIORITY JOURNAL; RISK ASSESSMENT; URIC ACID BLOOD LEVEL;

ADULT; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; HYPERTENSION; HYPERURICEMIA; KIDNEY DISEASES; MALE; MIDDLE AGED;

EID: 36349009700     PISSN: 08957061     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.amjhyper.2007.08.010     Document Type: Article

References (31)

1. Leoncini G., Viazzi F., Parodi D., Vettoretti S., Ratto E., Ravera M., Tomolillo C., Del Sette M., Bezante G.P., Deferrari G., and Pontremoli R. Mild renal dysfunction and subclinical cardiovascular damage in primary hypertension. Hypertension 42 (2003) 14-18
2. Alderman M.H., Cohen H., Madhavan S., and Kivlighn S. Serum uric acid and cardiovascular events in successfully treated hypertensive patients. Hypertension 34 (1999) 144-150
3. Baker J.F., Krishnan E., Chen L., and Schumacher H.R. Serum uric acid and cardiovascular disease: recent developments, and where do they leave us?. Am J Med 118 (2005) 816-826
4. Kang D.H., Park S.K., Lee I.K., and Johnson R.J. Uric acid-induced C-reactive protein expression: implication on cell proliferation and nitric oxide production of human vascular cells. J Am Soc Nephrol 16 (2005) 3553-3562
5. Khosla U.M., Zharikov S., Finch J.L., Nakagawa T., Roncal C., Mu W., Krotova K., Block E.R., Prabhakar S., and Johnson R.J. Hyperuricemia induces endothelial dysfunction. Kidney Int 67 (2005) 1739-1742
6. Zoccali C., Maio R., Mallamaci F., Sesti G., and Perticone F. Uric acid and endothelial dysfunction in essential hypertension. J Am Soc Nephrol 17 (2006) 1466-1471
7. Perlstein T.S., Gumieniak O., Hopkins P.N., Murphey L.J., Brown N.J., Williams G.H., Hollenberg N.K., and Fisher N.D. Uric acid and the state of the intrarenal renin-angiotensin system in humans. Kidney Int 66 (2004) 1465-1470
8. Johnson R.J., Kang D.H., Feig D., Kivlighn S., Kanellis J., Watanabe S., Tuttle K.R., Rodriguez-Iturbe B., Herrera-Acosta J., and Mazzali M. Is there a pathogenetic role for uric acid in hypertension and cardiovascular and renal disease?. Hypertension 41 (2003) 1183-1190
9. Pontremoli R., Sofia A., Ravera M., Nicolella C., Viazzi F., Tirotta A., Ruello N., Tomolillo C., Castello C., Grillo G., Sacchi G., and Deferrari G. Prevalence and clinical correlates of microalbuminuria in essential hypertension: the MAGIC Study. Hypertension 30 (1997) 1135-1143
10. Friedewald W.T., Levi R.I., and Fredrickson D.J. Estimation of the concentration of low density lipoprotein cholesterol in plasma without use of the ultracentrifuge. Clin Chem 18 (1972) 499-502
11. Grundy S.M., Cleeman J.I., Daniels S.R., Donato K.A., Eckel R.H., Franklin B.A., Gordon D.J., Krauss R.M., Savage P.J., Smith Jr. S.C., Spertus J.A., and Costa F. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 112 (2005) 2735-2752
12. European Society of Hypertension-European Society of Cardiology Guidelines Committee. 2003 European Society of Hypertension-European Society of Cardiology guidelines for the management of arterial hypertension. J Hypertens 21 (2003) 1011-1053
13. Cockcroft D.W., and Gault M.H. Prediction of creatinine clearance from serum creatinine. Nephron 16 (1976) 31-41
14. Mittelstaedt C.A. General Ultrasound (1992), Churchill, London 883-1042
15. Viazzi F., Leoncini G., Ratto E., and Pontremoli R. Serum uric acid as a risk factor for cardiovascular and renal disease: an old controversy revived. J Clin Hypertens 8 (2006) 510-518
16. Tseng C.H. Correlation of uric acid and urinary albumin excretion rate in patients with Type 2 diabetes mellitus in Taiwan. Kidney Int 68 (2005) 796-801
17. Viazzi F., Parodi D., Leoncini G., Parodi A., Falqui V., Ratto E., Vettoretti S., Bezante G.P., Del Sette M., Deferrari G., and Pontremoli R. Serum uric acid and target organ damage in primary hypertension. Hypertension 45 (2005) 991-996
18. Lee J.E., Kim Y.G., Choi Y.H., Huh W., Kim D.J., and Oh H.Y. Serum uric acid is associated with microalbuminuria in prehypertension. Hypertension 47 (2006) 962-967
19. Iseki K., Oshiro S., Tozawa M., Iseki C., Ikemiya Y., and Takishita S. Significance of hyperuricemia on the early detection of renal failure in a cohort of screened subjects. Hypertens Res 24 (2001) 691-697
20. Iseki K., Ikemiya Y., Inoue T., Iseki C., Kinjo K., and Takishita S. Significance of hyperuricemia as a risk factor for developing ESRD in a screened cohort. Am J Kidney Dis 44 (2004) 642-650
21. Domrongkitchaiporn S., Sritara P., Kitiyakara C., Stitchantrakul W., Krittaphol V., Lolekha P., Cheepudomwit S., and Yipintsoi T. Risk factors for development of decreased kidney function in a southeast Asian population: a 12-year cohort study. J Am Soc Nephrol 16 (2005) 791-799
22. Pontremoli R., Viazzi F., Martinoli C., Ravera M., Nicolella C., Berruti V., Leoncini G., Ruello N., Zagami P., Bezante G.P., Derchi L.E., and Deferrari G. Increased renal resistive index in patients with essential hypertension: a marker of target organ damage. Nephrol Dial Transplant 14 (1999) 360-365
23. Ratto E., Leoncini G., Viazzi F., Vaccaro V., Falqui V., Parodi A., Conti N., Tomolillo C., Deferrari G., and Pontremoli R. Ambulatory arterial stiffness index and renal abnormalities in primary hypertension. J Hypertens 24 (2006) 2033-2038
24. Derchi L.E., Leoncini G., Parodi D., Viazzi F., Martinoli C., Ratto E., Vettoretti S., Vaccaro V., Falqui V., Tomolillo C., Deferrari G., and Pontremoli R. Mild renal dysfunction and renal vascular resistance in primary hypertension. Am J Hypertens 18 (2005) 966-971
25. Messerli F.H., Frohlich E.D., Dreslinski G.R., Suarez D.H., and Aristimuno G.G. Serum uric acid in essential hypertension: an indicator of renal vascular involvement. Ann Intern Med 93 (1980) 817-821
26. Mazzali M., Kanellis J., Han L., Feng L., Xia Y.Y., Chen Q., Kang D.H., Gordon K.L., Watanabe S., Nakagawa T., Lan H.Y., and Johnson R.J. Hyperuricemia induces a primary renal arteriolopathy in rats by a blood pressure-independent mechanism. Am J Physiol Renal Physiol 282 (2002) 991-997
27. Price K.L., Sautin Y.Y., Long D.A., Zhang L., Miyazaki H., Mu W., Endou H., and Johnson R.J. Human vascular smooth muscle cells express a urate transporter. J Am Soc Nephrol 17 (2006) 1791-1795
28. Feig D.I., Rodriguez-Iturbe B., Nakagawa T., and Johnson R.J. Nephron number, uric acid, and renal microvascular disease in the pathogenesis of essential hypertension. Hypertension 48 (2006) 25-26
29. Schmidt I.M., Chellakooty M., Boisen K.A., Damgaard I.N., Mau Kai C., Olgaard K., and Main K.M. Impaired kidney growth in low-birth-weight children: distinct effects of maturity and weight for gestational age. Kidney Int 68 (2005) 731-740
30. Bax L., van der Graaf Y., Rabelink A.J., Algra A., Beutler J.J., Mali W.P., and SMART Study Group. Influence of atherosclerosis on age-related changes in renal size and function. Eur J Clin Invest 33 (2003) 34-40
31. Burkhardt H., Hahn T., and Gladisch R. Is kidney size a useful predictor of renal function in the elderly?. Clin Nephrol 59 (2003) 415-422