Absolute quantification of carnosine in human calf muscle by proton magnetic resonance spectroscopy

Physics in Medicine and Biology

Volumn 52, Issue 23, 2007, Pages 6781-6794

  Özdemir, Mahir S ^a   Reyngoudt, Harmen ^b   De Deene, Yves ^b   Sazak, Hakan S ^c   Fieremans, Els ^a   Delputte, Steven ^a   D'Asseler, Yves ^a   Derave, Wim ^a   Lemahieu, Ignace ^a   Achten, Eric ^b  

^a GHENT UNIVERSITY   (Belgium)

^b GHENT UNIVERSITY HOSPITAL   (Belgium)

^c EGE UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALS; BIOPSY; MAGNETIC RESONANCE SPECTROSCOPY; METABOLITES; MUSCLE;

BUFFERING CAPACITY; CARNOSINE; HUMAN CALF MUSCLE; PROTON MAGNETIC RESONANCE SPECTROSCOPY;

PEPTIDES;

CARNOSINE;

ARTICLE; ATHLETE; CELL FUNCTION; CELL PH; CONTROLLED STUDY; EXERCISE; FATIGUE; FEMALE; GASTROCNEMIUS MUSCLE; HUMAN; HUMAN EXPERIMENT; MALE; MUSCLE BIOPSY; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DETERMINATION; PROTON NUCLEAR MAGNETIC RESONANCE; PROTON TRANSPORT; QUANTITATIVE ANALYSIS; SKELETAL MUSCLE; SOLEUS MUSCLE;

ALGORITHMS; CARNOSINE; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MUSCLE, SKELETAL; PROTONS; THIGH; TISSUE DISTRIBUTION;

EID: 36349009306     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/52/23/001     Document Type: Article

References (33)

1. Abe H 2000 Role of histidine-related compounds as intracellular proton buffering constituents in vertebrate muscle Biochemistry 65 757-65
2. Alonso J, Arus C, Westler W M and Markley J 1990 Two-dimensional spectra of intact tissue: homonuclear Hartmann-Hahn spectroscopy provides increased sensitivity and information content as compared to COSY Magn. Reson. Med. 15 142-51
3. Bate-Smith E C 1938 The buffering of muscle in rigor: protein, phosphate and carnosine J. Physiol. 92 336-43
4. 1H-MRS Magn. Reson. Med. 37 484-93
5. Bottomley P A, Lee Y and Weiss R G 1997 Total creatine in muscle: imaging and quantification with proton MR spectroscopy Radiology 204 403-10
6. Bottomley P A and Weiss R G 2001 Noninvasive localized MR quantification of creatine kinase metabolites in normal and infarcted canine myocardium Radiology 219 411-8
7. Brown C E 1981 Interactions among carnosine, anserine, ophidine and copper in biochemical adaptation J. Theor. Biol. 88 245-56
8. 31P MRS NMR Biomed. 7 225-30
9. Crush K G 1970 Carnosine and related substances in animal tissues Comput. Biochem. Physiol. 34 3-30
10. Derave W, Özdemir M S, Harris R C, Pottier A, Reyngoudt H, Koppo K, Wise J A and Achten E 2007 Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters J. Appl. Physiol. 103 1736-43
11. Gulewitsch W and Amiradzibi S 1900 Uber das carnosine, eine neue organische Base des Fleischextraktes Ber. Dtsch. Chem. Ges. 33 1902-3
12. Harris R C, Dunnett M and Greenhaff P L 1998 Carnosine and taurine contents in individual fibers of human vastus lateralis muscle J. Sports Sci. 16 639-43
13. Harris R C, Tallon M J, Dunnett M, Boobis L, Coakley J, Kim H J, Fallowfield J L, Hill C A, Sale C and Wise J A 2006 The absorption of orally supplied β-alanine and its effect on muscle carnosine synthesis in human vastus lateralis Amino Acids 30 279-89
14. Hill C A, Harris R C, Kim H J, Harris B D, Sale C, Boobis L, Kim C K and Wise J A 2007 Influence of β-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity Amino Acids 32 225-33
15. Insko E K and Bolinger L 1993 Mapping of radiofrequency field J. Magn. Reson. Ser. A 103 82-5
16. Kreis R and Boesch C 1996 Spatially localized, one- and two-dimensional NMR spectroscopy and in vivo application to human muscle J. Magn. Reson. Ser. B 113 103-18
17. 1H-MR spectra of skeletal muscle: the case of carnosine ISMRM Proc. Int. Soc. Magn. Reson. Med. 31
18. 1H MR spectra of human skeletal muscle: the case of carnosine J. Magn. Reson. 137 350-7
19. Mannion A F, Jakeman P M, Dunnett M, Harris R C and Willan P L T 1992 Carnosine and anserine concentrations in the quadriceps femoris muscle of healthy humans Eur. J. Appl. Physiol. 64 47-50
20. 1H NMR Proc. Natl Acad. Sci. 85 7836-9
21. Schick F, Eismann B, Jung W I, Bongers H, Bunse M and Lutz O 1993 Comparison of localized proton NMR signals of skeletal muscle and fat tissue in vivo: two lipid compartments in muscle tissue Magn. Reson. Med. 29 158-67
22. 1H NMR spectroscopy J. Magn. Reson. 164 256-69
23. 1H NMR spectra J. Magn. Reson. 171 213-24
24. Scriver C R, Perry T L and Nutzenadel W 1983 The Metabolic Basis of Inherited Disease (New York: McGraw-Hill) pp 570-85
25. Soher B J, van Zijl P C M, Duyn J H and Barker P B 1996 Quantitative proton MR spectroscopic imaging of the human brain Magn. Reson. Med. 35 356-63
26. Suzuki Y, Ito O, Mukai N, Takahashi H and Takamatsu K 2002 High level of skeletal muscle carnosine contributes to the latter half of exercise performance during 30-s maximal cycle ergometer sprinting Japan. J. Physiol. 52 199-205
27. Tallon M J, Harris R C, Boobis L H, Fallowfield J L and Wise J A 2005 The carnosine content of vastus lateralis is elevated in resistance-trained bodybuilders J. Strength. Cond. Res. 19 725-9
28. Taylor R, Price T B, Rothman D L, Shulman R G and Shulman G I 1992 Validation of 13C NMR measurement of human skeletal muscle glycogen by direct biochemical assay of needle biopsy samples Magn. Reson. Med. 27 13-20
29. Tofts P 2003 Quantitative MRI of the Brain-Measuring Changes Caused by Diseases (Chichester: Wiley)
30. Tofts P S 1994 Standing waves in uniform water phantoms J. Magn. Reson. Ser. B 104 143-7
31. Tofts P S, Barker G J, Dean T L, Gallagher H, Gregory A P and Clarke R N 1997 A low dielectric constant customized phantom design to measure rf coil nonuniformity Magn. Reson. Imaging 15 69-75
32. Wendling P S, Peters S J, Heigenhauser J F and Spriet L L 1996 Variability of triacylglycerol content in human skeletal muscle biopsy samples J. Appl. Physiol. 81 1150-5
33. van der Veen J W C, Weinberger D R, Tedeschi G, Frank J A and Duyn J H 2000 Proton MR spectroscopic imaging without water suppression Radiology 217 296-300