Pharmacokinetics of the adrenocorticolytic compounds 3-methylsulphonyl-DDE and o,p′-DDD (mitotane) in Minipigs

Cancer Chemotherapy and Pharmacology

Volumn 61, Issue 2, 2008, Pages 267-274

  Hermansson, Veronica ^a   Cantillana, Tatiana ^b   Hovander, Lotta ^b   Bergman, Åke ^b   Ljungvall, Karl ^c   Magnusson, Ulf ^c   Törneke, Karolina ^d   Brandt, Ingvar ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b STOCKHOLM UNIVERSITY   (Sweden)

^c SWEDISH UNIVERSITY OF AGRICULTURAL SCIENCES   (Sweden)

^d MEDICAL PRODUCTS AGENCY   (Sweden)

Author keywords

3 MeSO2 DDE; Adrenal cortex; Minipig; Mitotane; o,p DDD; Pharmacokinetics

Indexed keywords

1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHANE; 3 METHYLSULPHONYL 1,1 DICHLORO 2,2 BIS(4 CHLOROPHENYL)ETHYLENE; ETHYLENE DERIVATIVE; MITOTANE; UNCLASSIFIED DRUG;

ADIPOSE TISSUE; ADRENAL CORTEX TUMOR; ANALYTIC METHOD; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; FEMALE; GAS CHROMATOGRAPHY; MINIPIG; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; SUBCUTANEOUS FAT;

ADIPOSE TISSUE; ADRENAL CORTEX; ANIMALS; ANTINEOPLASTIC AGENTS, HORMONAL; AREA UNDER CURVE; BIOTRANSFORMATION; CHROMATOGRAPHY, GAS; DATA INTERPRETATION, STATISTICAL; DICHLORODIPHENYL DICHLOROETHYLENE; ELECTROCHEMISTRY; LIVER; MITOTANE; SUBCUTANEOUS FAT; SWINE; SWINE, MINIATURE; TISSUE DISTRIBUTION;

EID: 36349008125     PISSN: 03445704     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00280-007-0468-x     Document Type: Article

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