Prostaglandin E2 induces hypertrophic changes and suppresses α-skeletal actin gene expression in rat cardiomyocytes

Journal of Cardiovascular Pharmacology

Volumn 50, Issue 5, 2007, Pages 548-554

  Miyatake, Satoru ^a   Manabe Kawaguchi, Haruko ^a   Watanabe, Kikuko ^b   Hori, Shingo ^a   Aikawa, Naoki ^a   Fukuda, Keiichi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF EAST ASIA   (Japan)

Author keywords

skeletal actin; Cardiac hypertrophy; Prostaglandin E2

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; 1,3 BUTADIENE DERIVATIVE; 4 (4 CYANO 2 (2 (4 FLUORONAPHTHALEN 1 YL)PROPIONYLAMINO)PHENYL)BUTYRIC ACID; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4-(4-CYANO-2-(2-(4-FLUORONAPHTHALEN-1-YL)PROPIONYLAMINO)PHENYL)BUTYRIC ACID; ACTIN; ARYLBUTYRIC ACID DERIVATIVE; EP4 RECEPTOR; IMIDAZOLE DERIVATIVE; NAPHTHALENE DERIVATIVE; NITRILE; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; PROTEIN KINASE INHIBITOR; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

ALPHA SKELETAL ACTIN; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENUATION; BIOLOGICAL ACTIVITY; CELL CULTURE; CELL SIZE; GENE EXPRESSION; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; IMMUNOFLUORESCENCE MICROSCOPY; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN INDUCTION; RAT; ANIMAL; CELL ENLARGEMENT; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; NEWBORN; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WISTAR RAT;

ACTINS; ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; BLOTTING, WESTERN; BUTADIENES; CELL ENLARGEMENT; CELL SIZE; CELLS, CULTURED; DINOPROSTONE; GENE EXPRESSION; IMIDAZOLES; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; MYOCYTES, CARDIAC; NAPHTHALENES; NATRIURETIC PEPTIDE, BRAIN; NITRILES; PHENYLBUTYRATES; PHOSPHORYLATION; PROSTAGLANDIN ANTAGONISTS; PROTEIN BIOSYNTHESIS; PROTEIN KINASE INHIBITORS; PYRIDINES; RATS; RATS, WISTAR; RECEPTORS, PROSTAGLANDIN E; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 36348999736     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/FJC.0b013e318145ae2e     Document Type: Article

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