Does correction of anemia slow the progression of chronic kidney disease?

Nature Clinical Practice Nephrology

Volumn 3, Issue 12, 2007, Pages 638-639

  Singh, Ajay K ^a,b,c,d  

^a Renal Division   (United States)

^b Dialysis Services   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ERYTHROPOIETIN; NOVEL ERYTHROPOIESIS STIMULATING PROTEIN;

ANEMIA; APOPTOSIS; CARDIOVASCULAR DISEASE; CELL PROTECTION; CHRONIC KIDNEY DISEASE; DISEASE COURSE; DOSE RESPONSE; GLOMERULUS FILTRATION RATE; HAZARD RATIO; HEMOGLOBIN BLOOD LEVEL; HUMAN; KIDNEY DISEASE; KIDNEY FAILURE; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY TUBULE CELL; MORTALITY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PUBLICATION; RENAL PROTECTION; SHORT SURVEY;

ANEMIA; ANIMALS; DISEASE PROGRESSION; HUMANS; RENAL INSUFFICIENCY, CHRONIC;

EID: 36348981641     PISSN: 17458323     EISSN: 17458331     Source Type: Journal    
DOI: 10.1038/ncpneph0637     Document Type: Short Survey

References (12)

1. Singh AK et al. (2006) Correction of anemia with epoetin alfa in chronic kidney disease. N Engl J Med 355: 2085-2098
2. Drueke TB et al. (2006) Normalization of hemoglobin level in patients with chronic kidney disease and anemia. N Engl J Med 355: 2071-2084
3. Besarab A et al. (1998) The effects of normal as compared with low hematocrit values in patients with cardiac disease who are receiving hemodialysis and epoetin. N Engl J Med 339: 584-590
4. Rossert JA (2002) Contribution of anaemia to progression of renal disease: a debate. Nephrol Dial Transplant 17 (Suppl 1): 60-66
5. Menne J et al. (2007) The continuous erythropoietin receptor activator affects different pathways of diabetic renal injury. J Am Soc Nephrol 18: 2046-2053
6. Logar CM et al. (2007) Darbepoetin alfa protects podocytes from apoptosis in vitro and in vivo. Kidney Int 72: 489-498
7. Mohanram A et al. (2004) Anemia and end-stage renal disease in patients with type 2 diabetes and nephropathy. Kidney Int 66: 1131-1138
8. Rossert J et al. (2005) Anemia management and chronic renal failure progression. Kidney Int Suppl 99: S76-S81
9. Gouva C et al. (2004) Treating anemia early in renal failure patients slows the decline of renal function: a randomized controlled trial. Kidney Int 66: 753-760
10. Garcia DL et al. (1988) Anemia lessens and its prevention with recombinant human erythropoietin worsens glomerular injury and hypertension in rats with reduced renal mass. Proc Natl Acad Sci USA 85: 6142-6146
11. Lafferty HM et al. (1991) Anemia ameliorates progressive renal injury in experimental DOCA-salt hypertension. J Am Soc Nephrol 1: 1180-1185
12. Ritz E et al. (2007) Target level for hemoglobin correction in patients with diabetes and CKD: primary results of the Anemia Correction in Diabetes (ACORD) Study. Am J Kidney Dis 49: 194-207