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Central Brain Tumor Registry of the US. Statistical report: primary brain tumors in the United States, 1998-2002. Hinsdale: Central Brain Tumor Registry of the US; 2005.
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Central Brain Tumor Registry of the US. Statistical report: primary brain tumors in the United States, 1998-2002. Hinsdale: Central Brain Tumor Registry of the US; 2005.
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2
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Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: A Children's Cancer Group study
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Packer RJ, Goldwein J, Nicholson HS, et al. Treatment of children with medulloblastomas with reduced-dose craniospinal radiation therapy and adjuvant chemotherapy: a Children's Cancer Group study. J Clin Oncol 1999; 17:2127-2136.
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Packer, R.J.1
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Nicholson, H.S.3
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Effects of medulloblastoma resections on outcome in children: A report from the Children's Cancer Group
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Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: A prospective study by the Children's Oncology Group
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Robertson PL, Muraszko KM, Holmes EJ, et al. Incidence and severity of postoperative cerebellar mutism syndrome in children with medulloblastoma: a prospective study by the Children's Oncology Group. J Neurosurg 2006; 105:444-451.
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Robertson, P.L.1
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Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma
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Excellent prospective randomized clinical trial that compared low-dose CSRT in average-risk medulloblastoma with two different chemotherapeutic regimens with similar EFS outcomes. It reveals that new regimens to reduce harmful side-effects may be possible in the future
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Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol 2006; 24:4202-4208. Excellent prospective randomized clinical trial that compared low-dose CSRT in average-risk medulloblastoma with two different chemotherapeutic regimens with similar EFS outcomes. It reveals that new regimens to reduce harmful side-effects may be possible in the future.
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J Clin Oncol
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Packer, R.J.1
Gajjar, A.2
Vezina, G.3
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6
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Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective, multicentre trial
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This comprehensive study illustrates the possible reduction in total chemotherapy duration and dose for a common pediatric brain tumor
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Gajjar A, Chintagumpala M, Ashley D, et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol 2006; 7:813-820. This comprehensive study illustrates the possible reduction in total chemotherapy duration and dose for a common pediatric brain tumor.
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Lancet Oncol
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Gajjar, A.1
Chintagumpala, M.2
Ashley, D.3
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7
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Outcome for children with medulloblastoma treated with radiation, cisplatin, CCNU, and vincristine chemotherapy
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Packer RJ, Sutton LN, Elterman R, et al. Outcome for children with medulloblastoma treated with radiation, cisplatin, CCNU, and vincristine chemotherapy. J Neurosurg 1994; 81:690-698.
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Packer, R.J.1
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8
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Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study
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Eberhart CG, Kepner JL, Goldthwaite PT, et al. Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study. Cancer 2002; 94:552-560.
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Eberhart, C.G.1
Kepner, J.L.2
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9
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β-catenin status predicts a favorable outcome in childhood medulloblastoma: The United Kingdom Children's Cancer Study Group brain tumour committee
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Ellison DW, Onilude OE, Lindsey JC, et al. β-catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group brain tumour committee. J Clin Oncol 2005; 23:7951-7957.
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Ellison, D.W.1
Onilude, O.E.2
Lindsey, J.C.3
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10
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Apoptosis suppression by somatic cell transfer of bcl-2 promotes sonic hedgehog-dependent medulloblastoma formation in mice
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McCall TD, Pedone CA, Fults DW. Apoptosis suppression by somatic cell transfer of bcl-2 promotes sonic hedgehog-dependent medulloblastoma formation in mice. Cancer Res 2007; 67:5179-5185.
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McCall, T.D.1
Pedone, C.A.2
Fults, D.W.3
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11
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Epidemiology of central nervous system neoplasms in childhood and adolescence based on the new WHO classification
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Rickert CH, Paulus W. Epidemiology of central nervous system neoplasms in childhood and adolescence based on the new WHO classification. Childs Nerv Syst 2001; 17:503-511.
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Childs Nerv Syst
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Rickert, C.H.1
Paulus, W.2
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12
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Gene expression patterns in ependymomas correlate with tumor location, grade, and patient
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Korshunov A, Neben K, Wrobel G, et al. Gene expression patterns in ependymomas correlate with tumor location, grade, and patient. Am J Pathol 2003; 163:1721-1727.
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Am J Pathol
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Korshunov, A.1
Neben, K.2
Wrobel, G.3
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13
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Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma
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Merchant TE, Mulhern RK, Krasin MJ, et al. Preliminary results from a phase II trial of conformal radiation therapy and evaluation of radiation-related CNS effects for pediatric patients with localized ependymoma. J Clin Oncol 2004; 22:3156-3162.
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J Clin Oncol
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Merchant, T.E.1
Mulhern, R.K.2
Krasin, M.J.3
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14
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0025300343
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Recurrent intracranial ependymomas in children: Survival, patterns of failure, and prognostic factors
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Goldwein JW, Glauser TA, Packer RJ, et al. Recurrent intracranial ependymomas in children: Survival, patterns of failure, and prognostic factors. Cancer 1990; 66:557-563.
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Goldwein, J.W.1
Glauser, T.A.2
Packer, R.J.3
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15
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33646886336
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Predicting which children are at risk for ependymoma relapse
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Sowar K, Straessle J, Donson AM, et al. Predicting which children are at risk for ependymoma relapse. J Neurooncol 2006; 78:41-46.
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J Neurooncol
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Sowar, K.1
Straessle, J.2
Donson, A.M.3
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16
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33645741644
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Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma
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Tabori U, Ma J, Carter M, et al. Human telomere reverse transcriptase expression predicts progression and survival in pediatric intracranial ependymoma. J Clin Oncol 2006; 24:1522-1528.
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J Clin Oncol
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Tabori, U.1
Ma, J.2
Carter, M.3
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17
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34247396134
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Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics
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Provides insights on novel molecular profiling techniques that may help characterize ependymoma more accurately in the future
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Modena P, Lualdi E, Facchinetti F. Identification of tumor-specific molecular signatures in intracranial ependymoma and association with clinical characteristics. J Clin Oncol 2006; 24:5223-5233. Provides insights on novel molecular profiling techniques that may help characterize ependymoma more accurately in the future.
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(2006)
J Clin Oncol
, vol.24
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Modena, P.1
Lualdi, E.2
Facchinetti, F.3
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18
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Radial glia cells are candidate stem cells of ependymoma
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Taylor MD, Poppleton H, Fuller C, et al. Radial glia cells are candidate stem cells of ependymoma. Cancer Cell 2005; 8:323-355.
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Cancer Cell
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Taylor, M.D.1
Poppleton, H.2
Fuller, C.3
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19
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33644850759
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Advances toward an understanding of brainstem gliomas
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Donaldson SS, Laningham F, Fisher PG. Advances toward an understanding of brainstem gliomas. J Clin Oncol 2006; 24:1266-1272.
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(2006)
J Clin Oncol
, vol.24
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Donaldson, S.S.1
Laningham, F.2
Fisher, P.G.3
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20
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24644518573
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Etoposide, vincristine, and cyclosporin A with standard-dose radiation in newly diagnosed diffuse intrinsic brainstem gliomas: A Pediatric Oncology Group phase I study
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Greenberg ML, Fisher PG, Freeman C, et al. Etoposide, vincristine, and cyclosporin A with standard-dose radiation in newly diagnosed diffuse intrinsic brainstem gliomas: a Pediatric Oncology Group phase I study. Pediatr Blood Cancer 2005; 45:644-648.
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Pediatr Blood Cancer
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Greenberg, M.L.1
Fisher, P.G.2
Freeman, C.3
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21
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37549026208
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Korones DN, Fisher Kretschmar C, et al. Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine, and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer 2007. [Epub ahead of print].
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Korones DN, Fisher PG, Kretschmar C, et al. Treatment of children with diffuse intrinsic brain stem glioma with radiotherapy, vincristine, and oral VP-16: a Children's Oncology Group phase II study. Pediatr Blood Cancer 2007. [Epub ahead of print].
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23
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33749599695
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Oeffinger KC, Mertens AC, Sklar CA, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med 2006; 355:1572-1582. Tracks survivors of childhood cancer through a retrospective cohort study known as the Childhood Cancer Survivor Study between 1970 and 1986, revealing a significant increase in chronic ailments when compared with their siblings.
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Oeffinger KC, Mertens AC, Sklar CA, et al. Chronic health conditions in adult survivors of childhood cancer. N Engl J Med 2006; 355:1572-1582. Tracks survivors of childhood cancer through a retrospective cohort study known as the Childhood Cancer Survivor Study between 1970 and 1986, revealing a significant increase in chronic ailments when compared with their siblings.
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24
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33947132078
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The late effects of childhood cancer therapy
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Discusses the difficulties that childhood cancer survivors face according to organ system. Recommendations are also suggested for monitoring these patients
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Dickerman JD. The late effects of childhood cancer therapy. Pediatrics 2007; 119:554-568. Discusses the difficulties that childhood cancer survivors face according to organ system. Recommendations are also suggested for monitoring these patients.
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(2007)
Pediatrics
, vol.119
, pp. 554-568
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Dickerman, J.D.1
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25
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16644394450
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Development of risk-based guidelines for pediatric cancer survivors: The Children's Oncology Group Long-Term Follow-Up Guidelines from the Children's Oncology Group Late Effects Committee and Nursing Discipline
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Landier W, Bhatia S, Eshelman DA, et al. Development of risk-based guidelines for pediatric cancer survivors: the Children's Oncology Group Long-Term Follow-Up Guidelines from the Children's Oncology Group Late Effects Committee and Nursing Discipline. J Clin Oncol 2004; 22:4979-4990.
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(2004)
J Clin Oncol
, vol.22
, pp. 4979-4990
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Landier, W.1
Bhatia, S.2
Eshelman, D.A.3
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26
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33750591336
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Neglia JP, Robison LL, Stovall M, et al. New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst 2006; 98:1528-1537. This large retrospective study compares patients treated for childhood malignancies with control subjects and identifies a significant risk of secondary neoplasms. The correlation with radiation dose and exposure is striking.
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Neglia JP, Robison LL, Stovall M, et al. New primary neoplasms of the central nervous system in survivors of childhood cancer: a report from the Childhood Cancer Survivor Study. J Natl Cancer Inst 2006; 98:1528-1537. This large retrospective study compares patients treated for childhood malignancies with control subjects and identifies a significant risk of secondary neoplasms. The correlation with radiation dose and exposure is striking.
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27
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33947496165
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Hijiya N, Hudson MM, Lensing S, et al. Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukaemia. JAMA 2007; 297:1207-1215. Provides insight from one institution's experience of a common and treatable pediatric cancer and the long-term effects of secondary malignancies.
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Hijiya N, Hudson MM, Lensing S, et al. Cumulative incidence of secondary neoplasms as a first event after childhood acute lymphoblastic leukaemia. JAMA 2007; 297:1207-1215. Provides insight from one institution's experience of a common and treatable pediatric cancer and the long-term effects of secondary malignancies.
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28
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34248172363
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Survival and late mortality in long-term survivors of pediatric CNS tumors
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This article reviews that not only is progressive disease a problem among pediatric brain tumor survivors, but the long-term sequelae of panhypopituitarism and other less obvious chronic conditions are ongoing issues
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Morris BE, Gajjar A, Okuma JO, et al. Survival and late mortality in long-term survivors of pediatric CNS tumors. J Clin Oncol 2007; 25:1532-1538. This article reviews that not only is progressive disease a problem among pediatric brain tumor survivors, but the long-term sequelae of panhypopituitarism and other less obvious chronic conditions are ongoing issues.
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(2007)
J Clin Oncol
, vol.25
, pp. 1532-1538
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Morris, B.E.1
Gajjar, A.2
Okuma, J.O.3
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29
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33847769663
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Late-occurring stroke among long-term survivors of childhood leukemia and brain tumors: A report from the childhood cancer survivor study
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Reveals stroke as a significant source of morbidity in the survivors of pediatric cancer and the risk associated with irradiation
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Bowers DC, Liu Y, Leisenring W, et al. Late-occurring stroke among long-term survivors of childhood leukemia and brain tumors: a report from the childhood cancer survivor study. J Clin Oncol 2006; 24:5277-5282. Reveals stroke as a significant source of morbidity in the survivors of pediatric cancer and the risk associated with irradiation.
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(2006)
J Clin Oncol
, vol.24
, pp. 5277-5282
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Bowers, D.C.1
Liu, Y.2
Leisenring, W.3
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30
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34247390661
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Changes in attentional performance of children and young adults with localized primary brain tumors after conformal radiation therapy
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Kiehna EN, Mulhern RK, Li C, et al. Changes in attentional performance of children and young adults with localized primary brain tumors after conformal radiation therapy. J Clin Oncol 2006; 24:5283-5290.
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(2006)
J Clin Oncol
, vol.24
, pp. 5283-5290
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Kiehna, E.N.1
Mulhern, R.K.2
Li, C.3
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31
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24944506884
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Profile of daily life in children with brain tumors: An assessment of health-related quality of life
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Bhat SR, Goodwin TL, Burwinkle TM, et al. Profile of daily life in children with brain tumors: an assessment of health-related quality of life. J Clin Oncol 2005; 23:5493-5500.
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(2005)
J Clin Oncol
, vol.23
, pp. 5493-5500
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Bhat, S.R.1
Goodwin, T.L.2
Burwinkle, T.M.3
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