The impact of molecular genetic diagnosis on the management of women with hCG-producing malignancies

Gynecologic Oncology

Volumn 107, Issue 3, 2007, Pages 413-419

  Fisher, Rosemary A ^a   Savage, Philip M ^a   MacDermott, Caitriona ^a   Hook, Jane ^a   Sebire, Neil J ^a   Lindsay, Iain ^a   Seckl, Michael J ^a  

^a CHARING CROSS HOSPITAL   (United Kingdom)

Author keywords

Choriocarcinoma; Genetic analysis; Gestational trophoblastic tumour; HCG

Indexed keywords

CHORIONIC GONADOTROPIN;

ADULT; ARTICLE; CELL DIFFERENTIATION; CHORIOCARCINOMA; CLINICAL ARTICLE; CONTROLLED STUDY; DEMOGRAPHY; DIFFERENTIAL DIAGNOSIS; FLUORESCENCE MICROSCOPY; GENETIC ANALYSIS; HISTOPATHOLOGY; HUMAN; MOLECULAR GENETICS; OVARY TUMOR; PATIENT CARE; PRIORITY JOURNAL; TROPHOBLASTIC TUMOR; UTERUS TUMOR;

ADULT; CHORIOCARCINOMA, NON-GESTATIONAL; CHORIONIC GONADOTROPIN; FEMALE; GESTATIONAL TROPHOBLASTIC NEOPLASMS; HUMANS; MIDDLE AGED; PREGNANCY;

EID: 36348945219     PISSN: 00908258     EISSN: 10956859     Source Type: Journal    
DOI: 10.1016/j.ygyno.2007.07.081     Document Type: Article

References (21)

1. Bower M., Newlands E.S., Holden L., et al. EMA/CO for high-risk gestational trophoblastic tumors: results from a cohort of 272 patients. J Clin Oncol 15 (1997) 2636-2643
2. McNeish I.A., Strickland S., Holden L., et al. Low-risk persistent gestational trophoblastic disease: outcome after initial treatment with low-dose methotrexate and folinic acid from 1992 to 2000. J Clin Oncol 20 (2002) 1838-1844
3. Stenman U.H., Alfthan H., and Hotakainen K. Human chorionic gonadotropin in cancer. Clin Biochem 37 (2004) 549-561
4. Fisher R.A., Newlands E.S., Jeffreys A.J., et al. Gestational and nongestational trophoblastic tumors distinguished by DNA analysis. Cancer 6 (1992) 839-845
5. Shigematsu T., Kamura T., Arima T., et al. DNA polymorphism analysis of a pure non-gestational choriocarcinoma of the ovary: case report. Eur J Gynaecol Oncol 21 (2000) 153-154
6. Suryanarayan K., O'Hanlan K.A., Surti U., et al. Nongestational choriocarcinoma in the postpartum period: a case report. J Pediatr Hematol Oncol 20 (1998) 169-173
7. Tsujioka H., Hamada H., Miyakawa T., et al. A pure nongestational choriocarcinoma of the ovary diagnosed with DNA polymorphism analysis. Gynecol Oncol 89 (2003) 540-542
8. Murugaesu N., Schmid P., Dancey G., et al. Malignant ovarian germ cell tumors: identification of novel prognostic markers and long-term outcome after multimodality treatment. J Clin Oncol 24 (2006) 4862-4866
9. Seckl M.J., Fisher R.A., Salerno G., et al. Choriocarcinoma and partial hydatidiform moles. Lancet 356 (2000) 36-39
10. Fisher R.A., Paradinas F.J., Newlands E.S., et al. Genetic evidence that placental site trophoblastic tumours can originate from a hydatidiform mole or a normal conceptus. Br J Cancer 65 (1992) 355-358
11. Palmieri C., Fisher R.A., Sebire N.J., et al. Placental site trophoblastic tumour arising from a partial hydatidiform mole. Lancet 366 (2005) 688
12. Kohorn E.I. The new FIGO 2000 staging and risk factor scoring system for gestational trophoblastic disease: description and critical assessment. Int J Gynecol Cancer 11 1 (Jan-Feb 2001) 73-77
13. Burke B., Sebire N.J., Moss J., et al. Evaluation of deletions in 7q11.2 and 8p12-p21 as prognostic indicators of tumour development following molar pregnancy. Gynecol Oncol 103 (2006) 642-648
14. GDB(TM) Human Genome Database [database online]. Toronto (Ontario, Canada): The Hospital for Sick Children, Baltimore (Maryland, USA): Johns Hopkins University, 1990. Available from Internet: URL http://www.gdb.org/
15. Osborne R., Covens A., Mirachandani D., et al. Successful salvage of relapsed high-risk gestational trophoblastic neoplasia patients using a novel paclitaxel-containing doublet. J Reprod Med 49 (2004) 655-661
16. Axe S.R., Klein V.R., and Woodruff J.D. Choriocarcinoma of the ovary. Obstet Gynecol 66 (1985) 111-114
17. Shahib N., Martaadisoebrata D., Kondo H., et al. Genetic origin of malignant trophoblastic neoplasms analyzed by sequence tag site polymorphic markers. Gynecol Oncol 81 (2001) 247-253
18. Powles T., Young A., Short D., et al. The outcome of patients with relapsed gestational trophoblastic neoplasm (GTN) after the completion of chemotherapy. J. Clin. Oncol., ASCO Annual Meeting Proceedings Part I vol. 24 (2006) 5033 June 20 Supplement
19. Fisher R.A., Soteriou B., Meredith L., et al. Previous hydatidiform mole identified as the causative pregnancy of choriocarcinoma following birth of normal twins. Int J Gynecol Cancer 5 (1995) 64-70
20. Cole L.A., Khanlian S.A., Muller C.Y., Giddings A., Kohorn E., and Berkowitz R. Gestational trophoblastic diseases: 3. Human chorionic gonadotropin-free beta-subunit, a reliable marker of placental site trophoblastic tumors. Gynecol Oncol 1002 2 (Aug 2006) 160-164
21. Cole L.A., Tanaka A., Kim G.S., Park S.Y., Koh M.W., Schwartz P.E., et al. Beta-core fragment (beta-core/UGF/UGP), a tumor marker: a 7-year report. Gynecol Oncol 60 2 (Feb 1996) 264-270