A reverse transcriptase assay for early diagnosis of infant HIV infection in resource-limited settings

Journal of Tropical Pediatrics

Volumn 53, Issue 5, 2007, Pages 355-358

  Sivapalasingam, Sumathi ^a   Patel, Usha ^b   Itri, Vincenza ^a   Laverty, Maura ^a   Mandaliya, Kishorchandra ^b   Valentine, Fred ^a   Essajee, Shaffiq ^a,b  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Obstetrics and Gynaecology   (Kenya)

Author keywords

Africa; Diagnosis; HIV; Infant; Reverse transcriptase

Indexed keywords

RNA DIRECTED DNA POLYMERASE;

ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CLINICAL TRIAL; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; COST BENEFIT ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INFANT; KENYA; PREDICTION; PRESCHOOL CHILD; SENSITIVITY AND SPECIFICITY; SEROLOGY; VIRUS LOAD;

COST CONTROL; DISEASE TRANSMISSION, VERTICAL; EARLY DIAGNOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HIV INFECTIONS; HIV-1; HUMANS; INFANT; INFANT, NEWBORN; KENYA; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RNA-DIRECTED DNA POLYMERASE; SENSITIVITY AND SPECIFICITY; VIRAL LOAD;

EID: 36249030537     PISSN: 01426338     EISSN: 14653664     Source Type: Journal    
DOI: 10.1093/tropej/fmm032     Document Type: Article

References (8)

1. Working Group on Antiretroviral Therapy and Medical Management of HIN-Infected Children. Guidelines for the use of antiretroviral agents in pediatric HIV infection. Available at: http://www.aidsinfo.nih.gov/ guidelines/pediatrice/PED_032405.pdf. Accessed 5 April 2005.
2. Cunningham CK, Charbonneau TT, Song K, et al. Comparison of human immunodeficiency virus 1 DNA polymerase chain reaction and qualitative and quantitative RNA polymerase chain reaction in human immunodeficiency virus 1-exposed infants. Pediatr Infect Dis J 1999;18:30-5.
3. Delamare C, Burgard M, Mayaux MJ, et al. HIV-1 RNA detection in plasma for the diagnosis of infection in neonates. The French Pediatric HIV Infection Study Group. J Acquir Immune Defic Syndr Hum Retrovirol 1997;15:121-5.
4. Steketee RW, Abrams EJ, Thea DM, et al. Early detection of perinatal human immunodeficiency virus (HIV) type I infection using HIV RNA amplification and detection. New York City Perinatal HIV Transmission Collaborative Study. J Infect Dis 1997; 175:707-11.
5. Malmsten A, Shao XW, Aperia K, et al. HIV-1 viral load determination based on reverse transcriptase activity recovered from human plasma. J Med Virol 2003;71:347-59.
6. Nduati R, John G, Mbori-Ngacha D, et al. Effect of breastfeeding and formula feeding on transmission of HIV- 1: A randomized clinical trial. JAMA 2000;283:1167-74.
7. Dunn DT, Brandt CD, Krivine, A, et al. The sensitivity of HIV- 1 DNA polymerase chain reaction in the neonatal period and the relative contributions of intra-uterine and intra-partum transmission. AIDS 1995;9:F7-11.
8. Nesheim S, Palumbo P, Sullivan K, et al. Quantitative RNA testing for diagnosis of HIV-infected infants. J Acquir Immune Defic Syndr 2003;32:192-5.