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1
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27944461383
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Engineering chromosomes for delivery of therapeutic genes
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A comprehensive review, which provides the basic information on artificial chromosome technologies, evaluates different strategies and discusses their advantages and problems.
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Irvine D.V., Shaw M.L., Choo K.H.A., and Saffery R. Engineering chromosomes for delivery of therapeutic genes. Trends Biotechnol 23 (2005) 575-583. A comprehensive review, which provides the basic information on artificial chromosome technologies, evaluates different strategies and discusses their advantages and problems.
-
(2005)
Trends Biotechnol
, vol.23
, pp. 575-583
-
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Irvine, D.V.1
Shaw, M.L.2
Choo, K.H.A.3
Saffery, R.4
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2
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3242780940
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Construction of a novel human artificial chromosome vector for gene delivery
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Description of the 21ΔHAC system. A useful 'cook-book' for generation of truncated human chromosomes by telomere-directed chromosome fragmentation.
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Katoh M., Ayabe F., Norikane S., Okada T., Masumoto H., Horike S., Shirayoshi Y., and Oshimura M. Construction of a novel human artificial chromosome vector for gene delivery. Biochem Biophys Res Commun 321 (2004) 280-290. Description of the 21ΔHAC system. A useful 'cook-book' for generation of truncated human chromosomes by telomere-directed chromosome fragmentation.
-
(2004)
Biochem Biophys Res Commun
, vol.321
, pp. 280-290
-
-
Katoh, M.1
Ayabe, F.2
Norikane, S.3
Okada, T.4
Masumoto, H.5
Horike, S.6
Shirayoshi, Y.7
Oshimura, M.8
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3
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34247130822
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Cryptic loxP sites in mammalian genomes: genome-wide distribution and relevance for the efficiency of BAC/PAC recombineering techniques
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Semprini S., Troup T.J., Kotelevtseva N., King K., Davis J.R., Mullins L.J., Chapman K.E., Dunbar D.R., and Mullins J.J. Cryptic loxP sites in mammalian genomes: genome-wide distribution and relevance for the efficiency of BAC/PAC recombineering techniques. Nucleic Acids Res 35 (2007) 1402-1410
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 1402-1410
-
-
Semprini, S.1
Troup, T.J.2
Kotelevtseva, N.3
King, K.4
Davis, J.R.5
Mullins, L.J.6
Chapman, K.E.7
Dunbar, D.R.8
Mullins, J.J.9
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4
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0033776128
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Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts
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Kuroiwa Y., Tomizuka K., Shinohara T., Kazuki Y., Yoshida H., Ohguma A., Yamamoto T., Tanaka S., Oshimura M., and Ishida I. Manipulation of human minichromosomes to carry greater than megabase-sized chromosome inserts. Nat Biotechnol 18 (2000) 1086-1090
-
(2000)
Nat Biotechnol
, vol.18
, pp. 1086-1090
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-
Kuroiwa, Y.1
Tomizuka, K.2
Shinohara, T.3
Kazuki, Y.4
Yoshida, H.5
Ohguma, A.6
Yamamoto, T.7
Tanaka, S.8
Oshimura, M.9
Ishida, I.10
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5
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8944236539
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De novo chromosome formations by large-scale amplification of the centromeric region of mouse chromosomes
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Kereso{combining double acute accent} J., Praznovszky T., Cserpán I., Fodor K., Katona R., Csonka E., Fátyol K., Holló G., Szeles A., Ross A.R., et al. De novo chromosome formations by large-scale amplification of the centromeric region of mouse chromosomes. Chromosome Res 4 (1996) 226-239
-
(1996)
Chromosome Res
, vol.4
, pp. 226-239
-
-
Kereso, J.1
Praznovszky, T.2
Cserpán, I.3
Fodor, K.4
Katona, R.5
Csonka, E.6
Fátyol, K.7
Holló, G.8
Szeles, A.9
Ross, A.R.10
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6
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0033785931
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Novel generation of human satellite DNA-based artificial chromosomes in mammalian cells
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Csonka E., Cserpán I., Fodor K., Holló G., Katona R., Kereso{combining double acute accent} J., Praznovszky T., Szakál B., Telenius A., deJong G., et al. Novel generation of human satellite DNA-based artificial chromosomes in mammalian cells. J Cell Sci 113 (2000) 3207-3216
-
(2000)
J Cell Sci
, vol.113
, pp. 3207-3216
-
-
Csonka, E.1
Cserpán, I.2
Fodor, K.3
Holló, G.4
Katona, R.5
Kereso, J.6
Praznovszky, T.7
Szakál, B.8
Telenius, A.9
deJong, G.10
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7
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15244355319
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A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy
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Description of the mammalian satellite DNA based ACE system, and the use of the ACE system for biological engineering of eukaryotic cells.
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Lindenbaum M., Perkins E., Csonka E., Fleming E., Garcia L., Greene A., Gung L., Hadlaczky G., Lee E., Leung J., et al. A mammalian artificial chromosome engineering system (ACE System) applicable to biopharmaceutical protein production, transgenesis and gene-based cell therapy. Nucleic Acids Res 32 21 (2004) e172. Description of the mammalian satellite DNA based ACE system, and the use of the ACE system for biological engineering of eukaryotic cells.
-
(2004)
Nucleic Acids Res
, vol.32
, Issue.21
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-
Lindenbaum, M.1
Perkins, E.2
Csonka, E.3
Fleming, E.4
Garcia, L.5
Greene, A.6
Gung, L.7
Hadlaczky, G.8
Lee, E.9
Leung, J.10
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8
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0033081317
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Mammalian artificial chromosome pilot facility: large-scale isolation of functional satellite DNA-based artificial chromosomes
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de Jong G., Telenius A.H., Telenius H., Perez C.F., Drayer J.I., and Hadlaczky G.Y. Mammalian artificial chromosome pilot facility: large-scale isolation of functional satellite DNA-based artificial chromosomes. Cytometry 35 (1999) 129-133
-
(1999)
Cytometry
, vol.35
, pp. 129-133
-
-
de Jong, G.1
Telenius, A.H.2
Telenius, H.3
Perez, C.F.4
Drayer, J.I.5
Hadlaczky, G.Y.6
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9
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0034065843
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Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection
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Co D.O., Borowski A.H., Leung J.D., van der Kaa J., Hengst S., Platenburg G.J., Pieper F.R., Perez C.F., Jirik F.R., and Drayer J.I. Generation of transgenic mice and germline transmission of a mammalian artificial chromosome introduced into embryos by pronuclear microinjection. Chromosome Res 8 (2000) 183-191
-
(2000)
Chromosome Res
, vol.8
, pp. 183-191
-
-
Co, D.O.1
Borowski, A.H.2
Leung, J.D.3
van der Kaa, J.4
Hengst, S.5
Platenburg, G.J.6
Pieper, F.R.7
Perez, C.F.8
Jirik, F.R.9
Drayer, J.I.10
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10
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2142768377
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Pronuclear microinjection of purified artificial chromosomes for generation of transgenic mice: pick-and-inject technique
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Monteith D.P., Leung J.D., Borowski A.H., Co D.O., Praznovszky T., Jirik F.R., Hadlaczky G., and Perez C.F. Pronuclear microinjection of purified artificial chromosomes for generation of transgenic mice: pick-and-inject technique. Methods Mol Biol 240 (2004) 227-242
-
(2004)
Methods Mol Biol
, vol.240
, pp. 227-242
-
-
Monteith, D.P.1
Leung, J.D.2
Borowski, A.H.3
Co, D.O.4
Praznovszky, T.5
Jirik, F.R.6
Hadlaczky, G.7
Perez, C.F.8
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11
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0030965015
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Functional expression and germline transmission of a human chromosome fragment in chimaeric mice
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Tomizuka K., Yoshida H., Uejima H., Kugoh H., Sato K., Ohguma A., Hayasaka M., Hanaoka K., Oshimura M., and Ishida I. Functional expression and germline transmission of a human chromosome fragment in chimaeric mice. Nat Genet 16 (1997) 133-143
-
(1997)
Nat Genet
, vol.16
, pp. 133-143
-
-
Tomizuka, K.1
Yoshida, H.2
Uejima, H.3
Kugoh, H.4
Sato, K.5
Ohguma, A.6
Hayasaka, M.7
Hanaoka, K.8
Oshimura, M.9
Ishida, I.10
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12
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0036714713
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Cloned transchromosomic calves producing human immunoglobulin
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Kuroiwa Y., Kasinathan P., Choi Y.J., Naeem R., Tomizuka K., Sullivan E.J., Knott J.G., Duteau A., Goldsby R.A., Osborne B.A., et al. Cloned transchromosomic calves producing human immunoglobulin. Nat Biotechnol 20 (2002) 889-894
-
(2002)
Nat Biotechnol
, vol.20
, pp. 889-894
-
-
Kuroiwa, Y.1
Kasinathan, P.2
Choi, Y.J.3
Naeem, R.4
Tomizuka, K.5
Sullivan, E.J.6
Knott, J.G.7
Duteau, A.8
Goldsby, R.A.9
Osborne, B.A.10
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13
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0037235359
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Artificial chromosome vectors and expression of complex proteins in transgenic animals
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Robl J.M., Kasinathan P., Sullivan E., Kuroiwa Y., Tomizuka K., and Ishida I. Artificial chromosome vectors and expression of complex proteins in transgenic animals. Theriogenology 59 (2003) 107-113
-
(2003)
Theriogenology
, vol.59
, pp. 107-113
-
-
Robl, J.M.1
Kasinathan, P.2
Sullivan, E.3
Kuroiwa, Y.4
Tomizuka, K.5
Ishida, I.6
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14
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36249031260
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Christmann L, Eberhardt DM, Leavitt MC, Harvey AJ: Artificial chromosomes and transchromosomic avians. United States Patent 20,06,01,74,364 http://www.freepatentsonline.com/20060174364.html.
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-
-
15
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36248992614
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Combs R, Yu E: Performance Evaluation of the ACE System Expressing an IgG1 MAb in the CHOK1SV Cell Line. IBC's 2nd Int Cell Line Dev Engineering: 2006 June 26-28. San Diego, CA.
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-
-
-
16
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36248987493
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-
Mott J: Incorporating the ACE System-An End User's Perspective. IBC's 2nd Int Cell Line Dev Engineering, 2006, June 26-28. San Diego, CA http://www.ibclifesciences.com/B3189/4645.xml.
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17
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36249007172
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Preuss D, Copenhaver G: Plant artificial chromosome compositions and methods. United States Patent 70,15,372 http://www.freepatentsonline.com/7015372.html.
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19
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34547411551
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Construction and behavior of engineered minichromosomes in maize
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This paper describes the basic steps toward the development of plant artificial chromosome systems using telomere-directed truncation of maize chromosomes with site-specific recombination cassettes.
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Yu W., Han F., Gao Z., Vega J.M., and Birchler J.A. Construction and behavior of engineered minichromosomes in maize. Proc Natl Acad Sci USA 104 (2007) 8924-8929. This paper describes the basic steps toward the development of plant artificial chromosome systems using telomere-directed truncation of maize chromosomes with site-specific recombination cassettes.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 8924-8929
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-
Yu, W.1
Han, F.2
Gao, Z.3
Vega, J.M.4
Birchler, J.A.5
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20
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36248979445
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Perez C, Fabijanski S, Perkins E: Plant artificial chromosomes, uses thereof and methods of preparing plant artificial chromosomes. United States Patent 20,06,01,43,732 http://www.freepatentsonline.com/20060143732.html.
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21
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27844596238
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Artificial and engineered chromosomes: developments and prospects for gene therapy
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This review summarizes recent advances in the construction of engineered chromosomes, and de novo human artificial chromosomes discuss development and challenges regarding the human gene therapy applications.
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Grimes B.R., and Monaco Z.L. Artificial and engineered chromosomes: developments and prospects for gene therapy. Chromosoma 114 (2005) 230-241. This review summarizes recent advances in the construction of engineered chromosomes, and de novo human artificial chromosomes discuss development and challenges regarding the human gene therapy applications.
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(2005)
Chromosoma
, vol.114
, pp. 230-241
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Grimes, B.R.1
Monaco, Z.L.2
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22
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18844424225
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Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts
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Kakeda M., Hiratsuka M., Nagata K., Kuroiwa Y., Kakitani M., Katoh M., Oshimura M., and Tomizuka K. Human artificial chromosome (HAC) vector provides long-term therapeutic transgene expression in normal human primary fibroblasts. Gene Ther 12 (2005) 852-856
-
(2005)
Gene Ther
, vol.12
, pp. 852-856
-
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Kakeda, M.1
Hiratsuka, M.2
Nagata, K.3
Kuroiwa, Y.4
Kakitani, M.5
Katoh, M.6
Oshimura, M.7
Tomizuka, K.8
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23
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31644435920
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A novel approach for gene therapy: engraftment of fibroblasts containing the artificial chromosome expression system at the site of inflammation
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Adriaansen J., Vervoordeldonk M.J., Vanderbyl S., de Jong G., and Tak P.P. A novel approach for gene therapy: engraftment of fibroblasts containing the artificial chromosome expression system at the site of inflammation. J Gene Med 8 (2006) 63-71
-
(2006)
J Gene Med
, vol.8
, pp. 63-71
-
-
Adriaansen, J.1
Vervoordeldonk, M.J.2
Vanderbyl, S.3
de Jong, G.4
Tak, P.P.5
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24
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2942622704
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Transfer and stable transgene expression of a mammalian artificial chromosome into bone marrow-derived human mesenchymal stem cells
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•] describes the successful transfer of ACs into human mesenchymal stem cells, expression of AC harbored transgenes in differentiated progeny of stem cells
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•] describes the successful transfer of ACs into human mesenchymal stem cells, expression of AC harbored transgenes in differentiated progeny of stem cells
-
(2004)
Stem Cells
, vol.22
, pp. 324-333
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Vanderbyl, S.1
MacDonald, G.N.2
Sidhu, S.3
Gung, L.4
Telenius, A.5
Perez, C.6
Perkins, E.7
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25
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27944464729
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A novel human artificial chromosome vector provides effective cell lineage-specific transgene expression
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•].
-
•].
-
(2005)
Stem Cells
, vol.23
, pp. 1608-1616
-
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Ren, X.1
Katoh, M.2
Hoshiya, H.3
Kurimasa, A.4
Inoue, T.5
Ayabe, F.6
Shibata, K.7
Toguchida, J.8
Oshimuraa, M.9
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26
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28844439761
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Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells
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This study is the first report demonstrating the transfer of a mammalian artificial chromosome and the stable expression of an encoded transgene in human hematopoietic cells.
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Vanderbyl S.L., Sullenbarger B., White N., Perez C.F., MacDonald G.N., Stodola T., Bunnell B.A., Ledebur Jr. H.C., and Lasky L.C. Transgene expression after stable transfer of a mammalian artificial chromosome into human hematopoietic cells. Exp Hematol 33 (2005) 1470-1476. This study is the first report demonstrating the transfer of a mammalian artificial chromosome and the stable expression of an encoded transgene in human hematopoietic cells.
-
(2005)
Exp Hematol
, vol.33
, pp. 1470-1476
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-
Vanderbyl, S.L.1
Sullenbarger, B.2
White, N.3
Perez, C.F.4
MacDonald, G.N.5
Stodola, T.6
Bunnell, B.A.7
Ledebur Jr., H.C.8
Lasky, L.C.9
-
27
-
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31544466578
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Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome
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Yamada H., Kunisato A., Kawahara M., Tahimic C.G., Ren X., Ueda H., Nagamune T., Katoh M., Inoue T., Nishikawa M., and Oshimura M. Exogenous gene expression and growth regulation of hematopoietic cells via a novel human artificial chromosome. J Hum Genet 51 (2006) 147-150
-
(2006)
J Hum Genet
, vol.51
, pp. 147-150
-
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Yamada, H.1
Kunisato, A.2
Kawahara, M.3
Tahimic, C.G.4
Ren, X.5
Ueda, H.6
Nagamune, T.7
Katoh, M.8
Inoue, T.9
Nishikawa, M.10
Oshimura, M.11
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