Adaptive group sequential test for clinical trials with changing patient population

Journal of Biopharmaceutical Statistics

Volumn 17, Issue 6, 2007, Pages 1227-1238

  Feng, Huaibao ^a   Shao, Jun ^a   Chow, Shein Chung ^b  

^a University of Wisconsin   (United States)

^b DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Changing patient population; Group sequential test; Protocol amendment; Type I error

Indexed keywords

CLINICAL PRACTICE; CLINICAL RESEARCH; COMPUTER SIMULATION; CONFERENCE PAPER; HEALTH CARE PLANNING; LINEAR REGRESSION ANALYSIS; MATHEMATICAL ANALYSIS; MEDICAL ERROR; PRIORITY JOURNAL; STATISTICAL ANALYSIS;

CLINICAL TRIALS AS TOPIC; HUMANS; RESEARCH DESIGN; SAMPLE SIZE;

EID: 36249016891     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543400701645512     Document Type: Conference Paper

References (6)

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2. Chow, S. C., Chang, M., Pong, A. (2005). Statistical consideration of adaptive methods in clinical development. Journal of Biopharmaceutical Statistics 15(4):575-591.
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6. Wang, S. K., Tsiatis, A. A. (1987). Approximately optimal one-parameter boundaries for group sequential trials. Biometrics 43:193-200.