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Volumn 19, Issue 6, 2007, Pages 513-520

Menorrhagia and bleeding disorders

Author keywords

Menorrhagia; Platelet function disorders; Von Willebrand's disease

Indexed keywords

BLOOD CLOTTING FACTOR 11; BLOOD CLOTTING FACTOR 5; BLOOD CLOTTING FACTOR 7; BLOOD CLOTTING FACTOR 8; BLOOD CLOTTING FACTOR 9; DESMOPRESSIN; FIBRINOLYTIC AGENT; IMMUNOGLOBULIN; ORAL CONTRACEPTIVE AGENT; PROTHROMBIN; RECOMBINANT BLOOD CLOTTING FACTOR 7A; STEROID; TRANEXAMIC ACID;

EID: 36249011307     PISSN: 1040872X     EISSN: None     Source Type: Journal    
DOI: 10.1097/GCO.0b013e3282f1ddbe     Document Type: Review
Times cited : (53)

References (86)
  • 1
    • 36248983522 scopus 로고    scopus 로고
    • Royal College of Obstetricians and Gynaecologists, London: Royal College of Obstetricians and Gynaecologists;
    • Royal College of Obstetricians and Gynaecologists. The initial management of menorrhagia: evidence based guidelines no. 1. London: Royal College of Obstetricians and Gynaecologists; 1998.
    • (1998) The initial management of menorrhagia: Evidence based guidelines , Issue.1
  • 3
    • 36248961947 scopus 로고    scopus 로고
    • Corrado M. Women's health in 1990. London: Market & Opinion Research International; 1990.
    • Corrado M. Women's health in 1990. London: Market & Opinion Research International; 1990.
  • 4
    • 36248993754 scopus 로고    scopus 로고
    • Chief Medical Officers report. London: Department of Health; 2006.
    • Chief Medical Officers report. London: Department of Health; 2006.
  • 6
    • 0029126989 scopus 로고
    • Indications for and outcome of total abdominal hysterectomy for benign disease: A prospective cohort study
    • Clarke A, Black N, Rowe P, et al. Indications for and outcome of total abdominal hysterectomy for benign disease: a prospective cohort study. Br J Obstet Gynaecol 1995; 102:611-620.
    • (1995) Br J Obstet Gynaecol , vol.102 , pp. 611-620
    • Clarke, A.1    Black, N.2    Rowe, P.3
  • 8
    • 26944447900 scopus 로고    scopus 로고
    • Society of Obstetricians and Gynecologists of Canada. Gynaecological and obstetric management of women with inherited bleeding disorders
    • Demers C, Derzko C, David M, Douglas J. Society of Obstetricians and Gynecologists of Canada. Gynaecological and obstetric management of women with inherited bleeding disorders. J Obstet Gynaecol Can 2005; 27:707-732.
    • (2005) J Obstet Gynaecol Can , vol.27 , pp. 707-732
    • Demers, C.1    Derzko, C.2    David, M.3    Douglas, J.4
  • 9
    • 0029972247 scopus 로고    scopus 로고
    • On the value of menorrhagia as a predictor for coagulation disorders
    • Edlund M, Blomback M, von Schoultz B, Andersson O. On the value of menorrhagia as a predictor for coagulation disorders. Am J Hematol 1996; 53:234-238.
    • (1996) Am J Hematol , vol.53 , pp. 234-238
    • Edlund, M.1    Blomback, M.2    von Schoultz, B.3    Andersson, O.4
  • 10
    • 0032515596 scopus 로고    scopus 로고
    • Frequency of inherited bleeding disorders in women with menorrhagia
    • Kadir RA, Economides DL, Sabin CA, et al. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet 1998; 351:485-489.
    • (1998) Lancet , vol.351 , pp. 485-489
    • Kadir, R.A.1    Economides, D.L.2    Sabin, C.A.3
  • 11
    • 34250741025 scopus 로고    scopus 로고
    • Kouides PA, Kadir RA. Menorrhagia associated with laboratory abnormalities of hemostasis: epidemiological, diagnostic and therapeutic aspects. J Thromb Haemost 2007; 5 (Suppl 1):175-182. Epidemiological studies have confirmed an association of vWf deficiency and menorrhagia with an incidence of vWf deficiency of 13, Such patients have a reduced quality of life and incur a high rate of unnecessary gynaecological interventions. Platelet function abnormalities are around three to four-fold more common than vWf deficiency in association with menorrhagia. Management of menorrhagia with an underlying disorder of hemostasis depends on the patient's age, childbearing status and preference in terms of several options. Comparative trials in bleeding disorder-related menorrhagia of intranasal desmopressin, tranexamic acid and the levonorgestrel intrauterine device are ongoing; specific recommendations cannot be made at present
    • Kouides PA, Kadir RA. Menorrhagia associated with laboratory abnormalities of hemostasis: epidemiological, diagnostic and therapeutic aspects. J Thromb Haemost 2007; 5 (Suppl 1):175-182. Epidemiological studies have confirmed an association of vWf deficiency and menorrhagia with an incidence of vWf deficiency of 13%. Such patients have a reduced quality of life and incur a high rate of unnecessary gynaecological interventions. Platelet function abnormalities are around three to four-fold more common than vWf deficiency in association with menorrhagia. Management of menorrhagia with an underlying disorder of hemostasis depends on the patient's age, childbearing status and preference in terms of several options. Comparative trials in bleeding disorder-related menorrhagia of intranasal desmopressin, tranexamic acid and the levonorgestrel intrauterine device are ongoing; specific recommendations cannot be made at present.
  • 13
  • 14
    • 0035076355 scopus 로고    scopus 로고
    • von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagia
    • Dilley A, Drews C, Miller C, et al. von Willebrand disease and other inherited bleeding disorders in women with diagnosed menorrhagia. Obstet Gynecol 2001; 97:630-636.
    • (2001) Obstet Gynecol , vol.97 , pp. 630-636
    • Dilley, A.1    Drews, C.2    Miller, C.3
  • 15
    • 0028201807 scopus 로고
    • A revised classification of von Willebrand disease. For the Subcommittee on von Willebrand Factor of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis
    • Sadler JE. A revised classification of von Willebrand disease. For the Subcommittee on von Willebrand Factor of the Scientific and Standardization Committee of the International Society on Thrombosis and Haemostasis. Thromb Haemost 1994; 71:520-525.
    • (1994) Thromb Haemost , vol.71 , pp. 520-525
    • Sadler, J.E.1
  • 17
    • 34250726088 scopus 로고    scopus 로고
    • Type 1 von Willebrand disease
    • Peake I, Goodeve A. Type 1 von Willebrand disease. J Thromb Haemost 2007; 5 (Suppl 1):7-11.
    • (2007) J Thromb Haemost , vol.5 , Issue.SUPPL. 1 , pp. 7-11
    • Peake, I.1    Goodeve, A.2
  • 18
    • 33748802581 scopus 로고    scopus 로고
    • Sadler JE, Budde U, Eikenboom CJ, et al. The Working Party on von Willebrand Disease Classification. Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand factor. J Thromb Haemost 2006; 4:2103-2114. Certain VWD types, especially type 1 and type 2A, encompass several pathophysiologic mechanisms that sometimes can be distinguished by appropriate laboratory studies. The clinical significance of this heterogeneity is under investigation, which may support further subdivision of VWD type 1 or type 2A in the future.
    • Sadler JE, Budde U, Eikenboom CJ, et al. The Working Party on von Willebrand Disease Classification. Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand factor. J Thromb Haemost 2006; 4:2103-2114. Certain VWD types, especially type 1 and type 2A, encompass several pathophysiologic mechanisms that sometimes can be distinguished by appropriate laboratory studies. The clinical significance of this heterogeneity is under investigation, which may support further subdivision of VWD type 1 or type 2A in the future.
  • 19
    • 0346097969 scopus 로고    scopus 로고
    • Polymorphism in the promoter region of von Willebrand factor gene and von Willebrand disease type 1
    • Simon D, Bandinelli E, Roisenberg I. Polymorphism in the promoter region of von Willebrand factor gene and von Willebrand disease type 1. Genet Mol Biol 2003; 26:397-401.
    • (2003) Genet Mol Biol , vol.26 , pp. 397-401
    • Simon, D.1    Bandinelli, E.2    Roisenberg, I.3
  • 20
    • 0018779080 scopus 로고
    • Genetics of classic von Willebrand's disease. I: Phenotypic variation within families
    • Miller CH, Graham JB, Goldin LR, Elston RC. Genetics of classic von Willebrand's disease. I: Phenotypic variation within families. Blood 1979; 54:117-136.
    • (1979) Blood , vol.54 , pp. 117-136
    • Miller, C.H.1    Graham, J.B.2    Goldin, L.R.3    Elston, R.C.4
  • 21
    • 0031194589 scopus 로고    scopus 로고
    • The revised classification of von Willebrand disease including the previously masqueraded female hemophilia A (type 2N)
    • Nishino M, Yoshioka A. The revised classification of von Willebrand disease including the previously masqueraded female hemophilia A (type 2N). Int J Hematol 1997; 66:21-30.
    • (1997) Int J Hematol , vol.66 , pp. 21-30
    • Nishino, M.1    Yoshioka, A.2
  • 22
    • 0032519496 scopus 로고    scopus 로고
    • Screening for von Willebrand disease with a new analyzer using high shear stress: A study of 60 cases
    • Fressinaud E, Veyradier A, Truchaud F, et al. Screening for von Willebrand disease with a new analyzer using high shear stress: a study of 60 cases. Blood 1998; 91:1325-1331.
    • (1998) Blood , vol.91 , pp. 1325-1331
    • Fressinaud, E.1    Veyradier, A.2    Truchaud, F.3
  • 23
    • 0035081481 scopus 로고    scopus 로고
    • Laboratory diagnosis of von Willebrand disorder(vWD) and monitoring of DDAVP therapy: Efficacy of PFA100 and vWF:CBA as combined diagnostic strategies
    • Favaloro EJ, Kershaw G, Bukuya M, et al. Laboratory diagnosis of von Willebrand disorder(vWD) and monitoring of DDAVP therapy: efficacy of PFA100 and vWF:CBA as combined diagnostic strategies. Haemophilia 2001; 7:180-189.
    • (2001) Haemophilia , vol.7 , pp. 180-189
    • Favaloro, E.J.1    Kershaw, G.2    Bukuya, M.3
  • 24
    • 0035080832 scopus 로고    scopus 로고
    • Utility of PFA-100 for assessing bleeding disorders and monitoring therapy: A review of analytical variables, benefits, and limitations
    • Favaloro EJ. Utility of PFA-100 for assessing bleeding disorders and monitoring therapy: a review of analytical variables, benefits, and limitations. Haemophilia 2001; 7:170-179.
    • (2001) Haemophilia , vol.7 , pp. 170-179
    • Favaloro, E.J.1
  • 25
    • 33645557848 scopus 로고    scopus 로고
    • Platelet function analyzer (PFA)-100_closure time in the evaluation of platelet disorders and platelet function
    • Hayward CPM, Harrison P, Cattaneo M, et al. Platelet function analyzer (PFA)-100_closure time in the evaluation of platelet disorders and platelet function. J Thromb Haemost 2006; 4:312-319.
    • (2006) J Thromb Haemost , vol.4 , pp. 312-319
    • Hayward, C.P.M.1    Harrison, P.2    Cattaneo, M.3
  • 26
    • 0033828195 scopus 로고    scopus 로고
    • von Willebrand disease in pediatric-based population comparison of type 1 diagnostic criteria and use of the PFA-100 and a von Willebrand factor/collagen-binding assay
    • Dean JA, Blanchette VS, Carcao MD, et al. von Willebrand disease in pediatric-based population comparison of type 1 diagnostic criteria and use of the PFA-100 and a von Willebrand factor/collagen-binding assay. Thromb Haemost 2000; 84:401-409.
    • (2000) Thromb Haemost , vol.84 , pp. 401-409
    • Dean, J.A.1    Blanchette, V.S.2    Carcao, M.D.3
  • 27
    • 0034912340 scopus 로고    scopus 로고
    • Obstetric and gynaecological aspects of von Willebrand disease
    • Kouides PA. Obstetric and gynaecological aspects of von Willebrand disease. Best Pract Res Clin Haematol 2001; 14:381-399.
    • (2001) Best Pract Res Clin Haematol , vol.14 , pp. 381-399
    • Kouides, P.A.1
  • 28
    • 0034486136 scopus 로고    scopus 로고
    • Clinical manifestations and complications of childbirth and replacement therapy in 385 Iranian patients with type 3 von Willebrand disease
    • Lak M, Peyvandi F, Mannucci PM. Clinical manifestations and complications of childbirth and replacement therapy in 385 Iranian patients with type 3 von Willebrand disease. Br J Haematol 2000; 111:1236-1240.
    • (2000) Br J Haematol , vol.111 , pp. 1236-1240
    • Lak, M.1    Peyvandi, F.2    Mannucci, P.M.3
  • 29
    • 0022507051 scopus 로고
    • Pregnancy in women with different types of von Willebrand disease
    • Conti M, Mari D, Conti E, et al. Pregnancy in women with different types of von Willebrand disease. Obstet Gynecol 1986; 68:282-285.
    • (1986) Obstet Gynecol , vol.68 , pp. 282-285
    • Conti, M.1    Mari, D.2    Conti, E.3
  • 30
    • 2342625955 scopus 로고    scopus 로고
    • Management of von Willebrand disease: Guidelines from the UK Haemophilia Centre Doctors' Organization
    • Pasi KJ, Collins PW, Keeling DM, et al. Management of von Willebrand disease: guidelines from the UK Haemophilia Centre Doctors' Organization. Haemophilia 2004; 10:218-231.
    • (2004) Haemophilia , vol.10 , pp. 218-231
    • Pasi, K.J.1    Collins, P.W.2    Keeling, D.M.3
  • 31
    • 0028363141 scopus 로고
    • Von Willebrand's disease, digestive angiodysplasia, and estrogen-progesterone treatment
    • Lavabre-Bertrand T, Navarro M, Blanc P, et al. Von Willebrand's disease, digestive angiodysplasia, and estrogen-progesterone treatment. Am J Hematol 1994; 46:254-255.
    • (1994) Am J Hematol , vol.46 , pp. 254-255
    • Lavabre-Bertrand, T.1    Navarro, M.2    Blanc, P.3
  • 32
    • 24444451856 scopus 로고    scopus 로고
    • An evaluation of the usefulness of PFA-100 device in 100 children referred for investigation of potential haemostatic disorder [abstract]
    • Burgess C, Credland P, Khair K, et al. An evaluation of the usefulness of PFA-100 device in 100 children referred for investigation of potential haemostatic disorder [abstract]. Haemophilia 2001; B247.
    • (2001) Haemophilia
    • Burgess, C.1    Credland, P.2    Khair, K.3
  • 33
    • 0025863197 scopus 로고
    • Nasal spray desmopressin (DDAVP) for mild hemophilia A and von Willebrand disease
    • Rose EH, Aledort LM. Nasal spray desmopressin (DDAVP) for mild hemophilia A and von Willebrand disease. Ann Intern Med 1991; 114:563-568.
    • (1991) Ann Intern Med , vol.114 , pp. 563-568
    • Rose, E.H.1    Aledort, L.M.2
  • 34
    • 0025901142 scopus 로고
    • Dimeric ristocetin flocculates proteins, binds to platelets, and mediates von Willebrand factor dependent agglutination of platelets
    • Scott JP, Montgomery RR, Retzinger GS. Dimeric ristocetin flocculates proteins, binds to platelets, and mediates von Willebrand factor dependent agglutination of platelets. J Biol Chem 1991; 266:8149-8155.
    • (1991) J Biol Chem , vol.266 , pp. 8149-8155
    • Scott, J.P.1    Montgomery, R.R.2    Retzinger, G.S.3
  • 35
    • 0023634567 scopus 로고
    • Intranasal and intravenous administration of desmopressin: Effect on F VIII/vWF, pharmacokinetics and reproducibility
    • Lethagen S, Harris AS, Sjorin E, Nilsson IM. Intranasal and intravenous administration of desmopressin: effect on F VIII/vWF, pharmacokinetics and reproducibility. Thromb Haemost 1987; 58:1033-1036.
    • (1987) Thromb Haemost , vol.58 , pp. 1033-1036
    • Lethagen, S.1    Harris, A.S.2    Sjorin, E.3    Nilsson, I.M.4
  • 36
  • 38
  • 39
    • 0343603909 scopus 로고    scopus 로고
    • Bleeding and thrombosis in 55 patients with inherited afibrinogenaemia
    • Lak M, Keihani M, Elahi F, et al. Bleeding and thrombosis in 55 patients with inherited afibrinogenaemia. Br J Haematol 1999; 107:204-206.
    • (1999) Br J Haematol , vol.107 , pp. 204-206
    • Lak, M.1    Keihani, M.2    Elahi, F.3
  • 40
    • 0018139784 scopus 로고
    • High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews
    • Seligsohn U. High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews. Blood 1978; 51:1223-1228.
    • (1978) Blood , vol.51 , pp. 1223-1228
    • Seligsohn, U.1
  • 41
    • 0034078947 scopus 로고    scopus 로고
    • Prenatal and peripartum management of congenital afibrinogenaemia
    • Kobayashi T, Kanayama N, Tokunaga N, et al. Prenatal and peripartum management of congenital afibrinogenaemia. Br J Haematol 2000; 109: 364-366.
    • (2000) Br J Haematol , vol.109 , pp. 364-366
    • Kobayashi, T.1    Kanayama, N.2    Tokunaga, N.3
  • 42
    • 0034078947 scopus 로고    scopus 로고
    • Prenatal and peripartum management of congenital afibrinogenaemia
    • Kobayashi T, Kanayama N, Togunaga M, et al. Prenatal and peripartum management of congenital afibrinogenaemia. Br J Haematol 2000; 109:364-366.
    • (2000) Br J Haematol , vol.109 , pp. 364-366
    • Kobayashi, T.1    Kanayama, N.2    Togunaga, M.3
  • 43
    • 0021847749 scopus 로고
    • Congenital afibrinogenemia and recurrent early abortion: A case report
    • Evron S, Anteby SO, Brzezinsky A, et al. Congenital afibrinogenemia and recurrent early abortion: a case report. Eur J Obstet Gynecol Reprod Biol 1985; 19:307-311.
    • (1985) Eur J Obstet Gynecol Reprod Biol , vol.19 , pp. 307-311
    • Evron, S.1    Anteby, S.O.2    Brzezinsky, A.3
  • 44
    • 0025917404 scopus 로고
    • Pregnancy in congenital afibrinogenaemia: Report of a successful case and review of the literature
    • Grech H, Majumdar G, Lawrie AS, Savidge GF. Pregnancy in congenital afibrinogenaemia: report of a successful case and review of the literature. Br J Hematol 1991; 78:571-572.
    • (1991) Br J Hematol , vol.78 , pp. 571-572
    • Grech, H.1    Majumdar, G.2    Lawrie, A.S.3    Savidge, G.F.4
  • 45
    • 0034975060 scopus 로고    scopus 로고
    • A database for human fibrinogen variants
    • Hanss M, Biot F. A database for human fibrinogen variants. Ann N Y Acad Sci 2001; 936:89-90.
    • (2001) Ann N Y Acad Sci , vol.936 , pp. 89-90
    • Hanss, M.1    Biot, F.2
  • 46
    • 4844229372 scopus 로고    scopus 로고
    • The rare coagulation disorders-review with guidelines for the management from the United Kingdom Haemophilia Centre Doctors' Organisation
    • Bolton-Maggs PHB, Perry DJ, Chalmers EA, et al. The rare coagulation disorders-review with guidelines for the management from the United Kingdom Haemophilia Centre Doctors' Organisation. Haemophilia 2004; 10: 593-628.
    • (2004) Haemophilia , vol.10 , pp. 593-628
    • Bolton-Maggs, P.H.B.1    Perry, D.J.2    Chalmers, E.A.3
  • 47
    • 0037279116 scopus 로고    scopus 로고
    • Guidelines on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders
    • UKHCDO
    • UKHCDO. Guidelines on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders. Haemophilia 2003; 9:1-23.
    • (2003) Haemophilia , vol.9 , pp. 1-23
  • 49
    • 0030891925 scopus 로고    scopus 로고
    • Factor V deficiency and menstruation: A gynecologic challenge
    • Bennett K, Daley ML, Pike C. Factor V deficiency and menstruation: a gynecologic challenge. Obstet Gynecol 1997; 89:839-840.
    • (1997) Obstet Gynecol , vol.89 , pp. 839-840
    • Bennett, K.1    Daley, M.L.2    Pike, C.3
  • 50
    • 0035129724 scopus 로고    scopus 로고
    • Current therapy for rare factor deficiencies
    • Di Paola J, Nugent D, Young G. Current therapy for rare factor deficiencies. Haemophilia 2001; 7 (Suppl. 1):16-22.
    • (2001) Haemophilia , vol.7 , Issue.SUPPL. 1 , pp. 16-22
    • Di Paola, J.1    Nugent, D.2    Young, G.3
  • 51
    • 0003538359 scopus 로고    scopus 로고
    • Severe congenital factor V deficiency: Successful management of bleedings by recombinant factor VIIa [abstract]
    • Borel-Derlon A, Gautier P, Le Querrec A, L'Hirondel JL. Severe congenital factor V deficiency: successful management of bleedings by recombinant factor VIIa [abstract]. Thromb Haemost 1999; 341 (Suppl):1079.
    • (1999) Thromb Haemost , vol.341 , Issue.SUPPL. , pp. 1079
    • Borel-Derlon, A.1    Gautier, P.2    Le Querrec, A.3    L'Hirondel, J.L.4
  • 52
    • 0033120795 scopus 로고    scopus 로고
    • ERGIC-53 gene structure and mutation analysis in 19 combined factors V and VIII deficiency families
    • Nichols WC, Terry VH, Wheatley MA, et al. ERGIC-53 gene structure and mutation analysis in 19 combined factors V and VIII deficiency families. Blood 1999; 93:2261-2266.
    • (1999) Blood , vol.93 , pp. 2261-2266
    • Nichols, W.C.1    Terry, V.H.2    Wheatley, M.A.3
  • 53
    • 0031028363 scopus 로고    scopus 로고
    • Linkage of combined factors V and VIII deficiency to chromosome 18q by homozygosity mapping
    • Nichols WC, Seligsohn U, Zivelin A, et al. Linkage of combined factors V and VIII deficiency to chromosome 18q by homozygosity mapping. J Clin Invest 1997; 99:596-601.
    • (1997) J Clin Invest , vol.99 , pp. 596-601
    • Nichols, W.C.1    Seligsohn, U.2    Zivelin, A.3
  • 54
    • 0032478548 scopus 로고    scopus 로고
    • Mutationsin the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII
    • Nichols WC, Seligsohn U, Zivelin A, et al. Mutationsin the ER-Golgi intermediate compartment protein ERGIC-53 cause combined deficiency of coagulation factors V and VIII. Cell 1998; 93:61-70.
    • (1998) Cell , vol.93 , pp. 61-70
    • Nichols, W.C.1    Seligsohn, U.2    Zivelin, A.3
  • 55
    • 0033120708 scopus 로고    scopus 로고
    • Molecular analysis of the ERGIC-53 gene in 35 families with combined factor V-factor VIII deficiency
    • Neerman-Arbez M, Johnson KM, Morris MA, et al. Molecular analysis of the ERGIC-53 gene in 35 families with combined factor V-factor VIII deficiency. Blood 1999; 93:2253-2260.
    • (1999) Blood , vol.93 , pp. 2253-2260
    • Neerman-Arbez, M.1    Johnson, K.M.2    Morris, M.A.3
  • 56
    • 0030762916 scopus 로고    scopus 로고
    • The locus for combined factor V-factor VIII deficiency (F5F8D) maps to 18q21, between D18S849 and D18S1103
    • Neerman-Arbez M, Antonarakis SE, Blouin JL, et al. The locus for combined factor V-factor VIII deficiency (F5F8D) maps to 18q21, between D18S849 and D18S1103. Am J Hum Genet 1997; 61:143-150.
    • (1997) Am J Hum Genet , vol.61 , pp. 143-150
    • Neerman-Arbez, M.1    Antonarakis, S.E.2    Blouin, J.L.3
  • 57
    • 0031854687 scopus 로고    scopus 로고
    • Combined factors V and VIII deficiency: The solution
    • Ginsburg D, Nichols WC, Zivelin A, et al. Combined factors V and VIII deficiency: the solution. Haemophilia 1998; 4:677-682.
    • (1998) Haemophilia , vol.4 , pp. 677-682
    • Ginsburg, D.1    Nichols, W.C.2    Zivelin, A.3
  • 58
    • 0020322169 scopus 로고
    • Combined factor V and factor VIII deficiency among non-Ashkenazi Jews
    • Seligsohn U, Zivelin A, Zwang E. Combined factor V and factor VIII deficiency among non-Ashkenazi Jews. N Engl J Med 1982; 307:1191-1195.
    • (1982) N Engl J Med , vol.307 , pp. 1191-1195
    • Seligsohn, U.1    Zivelin, A.2    Zwang, E.3
  • 59
    • 0031881892 scopus 로고    scopus 로고
    • Bleeding symptoms in 27 Iranian patients with the combined deficiency of factor V and factor VIII
    • Peyvandi F, Tuddenham EG, Akhtari AM, et al. Bleeding symptoms in 27 Iranian patients with the combined deficiency of factor V and factor VIII. Br J Haematol 1998; 100:773-776.
    • (1998) Br J Haematol , vol.100 , pp. 773-776
    • Peyvandi, F.1    Tuddenham, E.G.2    Akhtari, A.M.3
  • 60
    • 36248953008 scopus 로고
    • Two typical hereditary charts of congenital factor VII deficiency
    • Cleton FJ, Loeliger EA. Two typical hereditary charts of congenital factor VII deficiency. Thromb Diath Haemorrh 1980; 17:268-1268.
    • (1980) Thromb Diath Haemorrh , vol.17 , pp. 268-1268
    • Cleton, F.J.1    Loeliger, E.A.2
  • 61
    • 0024503368 scopus 로고
    • Factor VII deficiency and pregnancy
    • Fadel HE, Krauss JS. Factor VII deficiency and pregnancy. Obstet Gynecol 1989; 73:453-454.
    • (1989) Obstet Gynecol , vol.73 , pp. 453-454
    • Fadel, H.E.1    Krauss, J.S.2
  • 62
    • 0036040213 scopus 로고    scopus 로고
    • Factor VII deficiency
    • Perry DJ. Factor VII deficiency. Br J Haematol 2002; 118:689-700.
    • (2002) Br J Haematol , vol.118 , pp. 689-700
    • Perry, D.J.1
  • 63
    • 0025781484 scopus 로고
    • Haemorrhagic problems in obstetrics and gynaecology in patients with congenital coagulopathies
    • Greer IA, Lowe GD, Walker JJ, Forbes CD. Haemorrhagic problems in obstetrics and gynaecology in patients with congenital coagulopathies. Br J Obstet Gynaecol 1991; 98:909-918.
    • (1991) Br J Obstet Gynaecol , vol.98 , pp. 909-918
    • Greer, I.A.1    Lowe, G.D.2    Walker, J.J.3    Forbes, C.D.4
  • 64
    • 0001363327 scopus 로고
    • Sex chromatin and gene action in the mammalian x-chromosome
    • Lyon MF. Sex chromatin and gene action in the mammalian x-chromosome. Am J Hum Genet 1962; 14:135-148.
    • (1962) Am J Hum Genet , vol.14 , pp. 135-148
    • Lyon, M.F.1
  • 65
    • 0018139784 scopus 로고
    • High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews
    • Seligsohn U. High gene frequency of factor XI (PTA) deficiency in Ashkenazi Jews. Blood 1978; 51:1223-1228.
    • (1978) Blood , vol.51 , pp. 1223-1228
    • Seligsohn, U.1
  • 66
    • 0019404547 scopus 로고
    • Definition of the population at risk of bleeding due to factor XI deficiency in Ashkenazic Jews and the value of activated partial thromboplastin time in its detection
    • Seligsohn U, Modan M. Definition of the population at risk of bleeding due to factor XI deficiency in Ashkenazic Jews and the value of activated partial thromboplastin time in its detection. Isr J Med Sci 1981; 17:413-415.
    • (1981) Isr J Med Sci , vol.17 , pp. 413-415
    • Seligsohn, U.1    Modan, M.2
  • 67
    • 0032958492 scopus 로고    scopus 로고
    • Identification of a novel mutation in a non-Jewish factor deficient kindred
    • Alhaq A, Mitchell M, Sethi M, et al. Identification of a novel mutation in a non-Jewish factor deficient kindred. Br J Haematol 1999; 104:44-49.
    • (1999) Br J Haematol , vol.104 , pp. 44-49
    • Alhaq, A.1    Mitchell, M.2    Sethi, M.3
  • 68
    • 0036096074 scopus 로고    scopus 로고
    • Factor XI deficiency in Iranians: Its clinical manifestations in comparison with those of classic hemophilia
    • Peyvandi F, Lak M, Mannucci P. Factor XI deficiency in Iranians: its clinical manifestations in comparison with those of classic hemophilia. Haematologica 2002; 87:512-514.
    • (2002) Haematologica , vol.87 , pp. 512-514
    • Peyvandi, F.1    Lak, M.2    Mannucci, P.3
  • 69
    • 0031054862 scopus 로고    scopus 로고
    • In vivo coagulation activation following infusion of highly purified factor XI concentrate
    • Richards EM, Makris MM, Cooper P, Preston FE. In vivo coagulation activation following infusion of highly purified factor XI concentrate. Br J Haematol 1997; 96:293-297.
    • (1997) Br J Haematol , vol.96 , pp. 293-297
    • Richards, E.M.1    Makris, M.M.2    Cooper, P.3    Preston, F.E.4
  • 70
    • 0030707875 scopus 로고    scopus 로고
    • Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency
    • Evans G, Pasi KJ, Mehta A, et al. Recurrent venous thromboembolic disease and factor XI concentrate in a patient with severe factor XI deficiency, chronic myelomonocytic leukaemia, factor V Leiden and heterozygous plasminogen deficiency. Blood Coagul Fibrinolysis 1997; 8:437-440.
    • (1997) Blood Coagul Fibrinolysis , vol.8 , pp. 437-440
    • Evans, G.1    Pasi, K.J.2    Mehta, A.3
  • 71
    • 0021237190 scopus 로고
    • Idiopathic thrombocytopenia, initial illness and long term follow up
    • Walker RW, Walker W. Idiopathic thrombocytopenia, initial illness and long term follow up. Arch Dis Child 1984; 59:316-322.
    • (1984) Arch Dis Child , vol.59 , pp. 316-322
    • Walker, R.W.1    Walker, W.2
  • 72
    • 0037648477 scopus 로고    scopus 로고
    • Guidelines for the investigation and management of idiopathic thrombocytopenic purpura on adults, children, and in pregnancy
    • Provan D, Newland A, Norfolk D, et al. Guidelines for the investigation and management of idiopathic thrombocytopenic purpura on adults, children, and in pregnancy. Br J Haematol 2003; 120:574-596.
    • (2003) Br J Haematol , vol.120 , pp. 574-596
    • Provan, D.1    Newland, A.2    Norfolk, D.3
  • 73
    • 0017326775 scopus 로고
    • Management of idiopathic thrombocytopenic purpura in the adult
    • Lacey JV, Penner JA. Management of idiopathic thrombocytopenic purpura in the adult. Semin Thromb Hemost 1977; 3:160-174.
    • (1977) Semin Thromb Hemost , vol.3 , pp. 160-174
    • Lacey, J.V.1    Penner, J.A.2
  • 74
    • 0025635920 scopus 로고
    • Lack of increased bleeding after liver biopsy in patients with mild hemostatic abnormalities
    • McVay PA, Toy PT. Lack of increased bleeding after liver biopsy in patients with mild hemostatic abnormalities. Am J Clin Pathol 1990; 94:747-753.
    • (1990) Am J Clin Pathol , vol.94 , pp. 747-753
    • McVay, P.A.1    Toy, P.T.2
  • 75
    • 0025969408 scopus 로고
    • Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities
    • McVay PA, Toy PT. Lack of increased bleeding after paracentesis and thoracentesis in patients with mild coagulation abnormalities. Transfusion 1991; 31:164-171.
    • (1991) Transfusion , vol.31 , pp. 164-171
    • McVay, P.A.1    Toy, P.T.2
  • 76
    • 0016643620 scopus 로고
    • Clinical and genetic aspects of Glanzmann's thrombasthenia in Israel: Report of 22 cases
    • Reichert N, Seligsohn U, Ramot B. Clinical and genetic aspects of Glanzmann's thrombasthenia in Israel: report of 22 cases. Thromb Diath Haemorrh 1975; 34:806-820.
    • (1975) Thromb Diath Haemorrh , vol.34 , pp. 806-820
    • Reichert, N.1    Seligsohn, U.2    Ramot, B.3
  • 78
    • 0016786094 scopus 로고
    • Molecular differences of exposed surface proteins on thrombasthenic platelet plasma membranes
    • Phillips DR, Jenkins CS, Luscher EF, Larrieu M. Molecular differences of exposed surface proteins on thrombasthenic platelet plasma membranes. Nature 1975; 257:599-600.
    • (1975) Nature , vol.257 , pp. 599-600
    • Phillips, D.R.1    Jenkins, C.S.2    Luscher, E.F.3    Larrieu, M.4
  • 79
    • 0017666910 scopus 로고
    • Platelet membrane defects in Glanzmann's thrombasthenia: Evidence for decreased amounts of two major glycoproteins
    • Phillips DR, Agin PP. Platelet membrane defects in Glanzmann's thrombasthenia: evidence for decreased amounts of two major glycoproteins. J Clin Invest 1977; 60:535-545.
    • (1977) J Clin Invest , vol.60 , pp. 535-545
    • Phillips, D.R.1    Agin, P.P.2
  • 80
    • 0018834172 scopus 로고
    • Immunochemical evidence for protein abnormalities in platelets from patients with Glanzmann's thrombasthenia and Bernard-Soulier syndrome
    • Hagen I, Nurden A, Bjerrum OJ, et al. Immunochemical evidence for protein abnormalities in platelets from patients with Glanzmann's thrombasthenia and Bernard-Soulier syndrome. J Clin Invest 1980; 65:722-731.
    • (1980) J Clin Invest , vol.65 , pp. 722-731
    • Hagen, I.1    Nurden, A.2    Bjerrum, O.J.3
  • 81
    • 0022502039 scopus 로고
    • Acquired thrombasthenia due to GPIIb/IIIa-specific platelet autoantibodies
    • Niessner H, Clemetson KJ, Panzer S, et al. Acquired thrombasthenia due to GPIIb/IIIa-specific platelet autoantibodies. Blood 1986; 68:571-576.
    • (1986) Blood , vol.68 , pp. 571-576
    • Niessner, H.1    Clemetson, K.J.2    Panzer, S.3
  • 82
    • 0022615123 scopus 로고
    • A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder
    • DiMinno G, Coraggio F, Cerbone AM, et al. A myeloma paraprotein with specificity for platelet glycoprotein IIIa in a patient with a fatal bleeding disorder. J Clin Invest 1986; 77:157-164.
    • (1986) J Clin Invest , vol.77 , pp. 157-164
    • DiMinno, G.1    Coraggio, F.2    Cerbone, A.M.3
  • 83
    • 0021602988 scopus 로고
    • Molecular defects in interactions of platelets with the vessel wall
    • George JN, Nurden AT, Phillips DR. Molecular defects in interactions of platelets with the vessel wall. N Engl J Med 1984; 311:1084-1098.
    • (1984) N Engl J Med , vol.311 , pp. 1084-1098
    • George, J.N.1    Nurden, A.T.2    Phillips, D.R.3
  • 84
    • 0011518318 scopus 로고
    • Glycoprotein defects responsible for abnormal platelet functions in inherited disorders
    • George JN, Nurden AT, Phillips DR, editors, New York: Plenum;
    • Nurden AT. Glycoprotein defects responsible for abnormal platelet functions in inherited disorders. In: George JN, Nurden AT, Phillips DR, editors. Platelet membrane glycoproteins. New York: Plenum; 1985. pp. 357-371.
    • (1985) Platelet membrane glycoproteins , pp. 357-371
    • Nurden, A.T.1
  • 85
    • 0023874651 scopus 로고
    • An acquired Bernard-Soulier-like platelet defect associated with juvenile myelodysplastic syndrome
    • Berndt MC, Kabral A, Grimsley P, et al. An acquired Bernard-Soulier-like platelet defect associated with juvenile myelodysplastic syndrome. Br J Haematol 1988; 68:97-101.
    • (1988) Br J Haematol , vol.68 , pp. 97-101
    • Berndt, M.C.1    Kabral, A.2    Grimsley, P.3
  • 86
    • 36249022972 scopus 로고
    • DDAVP shortens the bleeding time in Bernard-Soulier syndrome
    • Cuthbert RJ, Watson HH, Handa SI, et al. DDAVP shortens the bleeding time in Bernard-Soulier syndrome. Thromb Res 1988; 110:217-223.
    • (1988) Thromb Res , vol.110 , pp. 217-223
    • Cuthbert, R.J.1    Watson, H.H.2    Handa, S.I.3


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