Combining esters of para-hydroxy benzoic acid (parabens) to achieve increased antimicrobial activity

Journal of Clinical Pharmacy and Therapeutics

Volumn 32, Issue 6, 2007, Pages 567-572

  Charnock, C ^a   Finsrud, T ^a  

^a OSLO METROPOLITAN UNIVERSITY   (Norway)

Author keywords

Increased antimicrobial efficacy; Novel combinations; Parabens

Indexed keywords

4 HYDROXYBENZOIC ACID ESTER; BUTYL PARABEN; DRUG PRESERVATIVE; ETHYL PARABEN; METHYL PARABEN; PILOCARPINE; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PROPYL PARABEN; WATER OIL CREAM;

ANTIMICROBIAL ACTIVITY; AQUEOUS SOLUTION; ARTICLE; BACTERIAL STRAIN; CANDIDA ALBICANS; CONTROLLED STUDY; CULTURE MEDIUM; DRUG EFFECT; DRUG EFFICACY; HUMAN; HUMAN CELL; IN VITRO STUDY; INOCULATION; MINIMUM INHIBITORY CONCENTRATION; PATIENT SAFETY; PSEUDOMONAS AERUGINOSA; STAPHYLOCOCCUS AUREUS; ZYGOSACCHAROMYCES;

DRUG COMBINATIONS; ESTERS; MICROBIAL SENSITIVITY TESTS; PARABENS; PRESERVATIVES, PHARMACEUTICAL;

EID: 36249009759     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2007.00854.x     Document Type: Article

References (14)

1. Elder RL (1984) Final report on the safety assessment of methylparaben, ethylparaben, propylparaben and butylparaben. Journal of the American College of Toxicology, 3, 147 209.
2. Cosmetic Ingredient Review (1994) Final report on the safety assessment of methylparaben, propylparaben and butylparaben. Journal of the American College of Toxicology, 14, 364 372.
3. Cosmetic Ingredient Review (1995) Final report on the safety assessment of isobutylparaben and isopropylparaben. Journal of the American College of Toxicology, 14, 364 372.
4. Soni MG, Burdock GA, Taylor SL et al. (2001) Safety assessment of propyl paraben: a review of the published literature. Food and Chemical Toxicology, 39, 513 532.
5. Soni MG, Taylor SL, Greenberg NA et al. (2002) Evaluation of the health aspects of methyl paraben: a review of the published literature. Food and Chemical Toxicology, 40, 1335 1373.
6. Murrell WG, Vincent JM (1950) The 4-hydroxybenzoic acid esters and related compounds. 4. The bacteriostatic action of 4-hydroxybenzoic acid n-alkyl esters. Journal of the Society of Chemistry, 69, 109 113.
7. Golden R, Gandy J, Vollmer G (2005) A review of the endocrine activity of parabens and implications for potential risks to human health. Critical Reviews in Toxicology, 35, 435 458.
8. Doron S, Friedman M, Falach M et al. (2001) Antibacterial effect of parabens against planktonic and biofilm Streptococcus sobrinus. International Journal of Antimicrobial Agents, 18, 575 578.
9. Ma Y, Marquis RE (1996) Irreversible paraben inhibition of glycolysis by Streptococcus mutans GS-5. Letters in Applied Microbiology, 23, 329 333.
10. Routledge EJ, Parker J, Odum J et al. (1998) Some alkyl hydroxy benzoate preservatives (parabens) are estrogenic. Toxicology and Applied Pharmacology, 153, 12 19.
11. European Directorate for the quality of medicines (2002) European Pharmacopoeia, 4th edn. Strasbourg, France : Council of Europe.
12. European Committee on Antibiotic Susceptibility (2002) Method for the determination of minimal inhibitory concentration (MIC) by broth dilution of fermentative yeasts. Discussion document E. Dis. 7.1. Taufkirchen, Germany : European Society of Clinical Microbiology and Infectious Diseases.
13. Charnock C, Finsrud T, Foss C (2004) Controlling the proliferation of Zygosaccharomyces bailii in ephedrine anti-phlegm cough mixture. Journal of Clinical Pharmacology and Therapeutics, 30, 325 329.
14. Norges Apotekerforening (Norwegian Pharmacy Association) (1980) Formel Samling, Majorstuen, 0310 Oslo, Norway.