Objective assessment of cancer biomarkers using semi-rare event detection

Cellular Oncology

Volumn 29, Issue 6, 2007, Pages 483-495

  Van Der Laak, Jeroen A W M ^a   Siebers, Albertus G ^a   Aalders, Sabine A A P ^a   Grefte, Johanna M M ^a   De Wilde, Peter C M ^a   Bulten, Johan ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Automated image analysis; Cervical cytology; Immunocytochemistry; p16INK4a protein; Rare event detection

Indexed keywords

PROTEIN P16INK4A; TUMOR MARKER; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; AUTOMATION; CANCER CELL; CARCINOGENESIS; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; DISEASE MARKER; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN TISSUE; IMAGE DISPLAY; IMMUNOCYTOCHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REPRODUCIBILITY; UTERINE CERVIX CANCER; UTERINE CERVIX CYTOLOGY;

CERVIX UTERI; CYCLIN-DEPENDENT KINASE INHIBITOR P16; DISCRIMINANT ANALYSIS; EVALUATION STUDIES AS TOPIC; FEMALE; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; IMMUNOHISTOCHEMISTRY; REPRODUCIBILITY OF RESULTS; TUMOR MARKERS, BIOLOGICAL; UTERINE CERVICAL NEOPLASMS; VAGINAL SMEARS;

EID: 36249005969     PISSN: 15705870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. B.T. Andersen, C. Pfeifer, E.R. Clausen et al., Improvement of the CINtec(TM) p16(INK4a) assay for identifying cervical high-grade lesions in cytology, Cytopathology 16(Supl. 2) (2006), 57.
2. K. Astbury, C.M. Martin, M. Ring et al., Future molecular aspects of cervical cytology, Curr. Diagn. Pathol. 12 (2006), 104-113.
3. J. Bulten, I. van der Avoort, W.J. Melchers et al., p14ARF and p16INK4A, two products of the same gene, are differently expressed in cervical intraepithelial neoplasia, Gynecol. Oncol. 101 (2006), 487-494.
4. R.C. Gonzalez and R.E. Woods, Digital Image Processing, Addison-Wesley Publishing Company, Reading, Massachusetts, 1992.
5. M.P. Grobusch, T. Hanscheid, B. Kramer et al., Sensitivity of hemozoin detection by automated flow cytometry in non- and semi-immune malaria patients, Cytometry 55B (2003), 46-51.
6. H.J. Gross, B. Verwer, D. Houck et al., Model study detecting breast cancer cells in peripheral blood mononuclear cells at frequencies as low as 10(-7), Proc. Natl. Acad. Sci. USA 92 (1995), 537-541.
7. H.J. Gundersen, T.F. Bendtsen, L. Korbo et al., Some new, simple and efficient stereological methods and their use in pathological research and diagnosis, APMIS 96 (1988), 379-394.
8. A.N. Kalof, M.F. Evans, L. Simmons-Arnold et al., p16INK4A immunoexpression and HPV in situ hybridization signal patterns: potential markers of high-grade cervical intraepithelial neoplasia, Am. J. Surg. Pathol. 29 (2005), 674-679.
9. R. Klaes, A. Benner, T. Friedrich et al., p16INK4a immunohistochemistry improves interobserver agreement in the diagnosis of cervical intraepithelial neoplasia, Am. J. Surg. Pathol. 26 (2002), 1389-1399.
10. R. Klaes, T. Friedrich, D. Spitkovsky et al., Overexpression of p16(INK4A) as a specific marker for dysplastic and neoplastic epithelial cells of the cervix uteri, Int. J. Cancer 92 (2001), 276-284.
11. S.K. Kraeft, R. Sutherland, L. Gravelin et al., Detection and analysis of cancer cells in blood and bone marrow using a rare event imaging system, Clin. Cancer Res. 6 (2000), 434-442.
12. R.K. Kumar, G.M. Velan, S.O. Korell et al., Virtual microscopy for learning and assessment in pathology, J. Pathol. 204 (2004), 613-618.
13. A. Ladanyi, A.C. Sher, A. Herlitz et al., Automated detection of immunofluorescently labeled cytomegalovirus-infected cells in isolated peripheral blood leukocytes using decision tree analysis, Cytometry 58A (2004), 147-156.
14. F. McQueen and E. Duvall, Using a quality control approach to define an 'adequately cellular' liquid-based cervical cytology specimen, Cytopathology 17 (2006), 168-174.
15. W.E. Mesker, F.S. Doekhie, J. Vrolijk et al., Automated analysis ofmultiple sections for the detection of occult cells in lymph nodes, Clin. Cancer Res. 9 (2003), 4826-4834.
16. W.E. Mesker, H. Torrenga, W.C. Sloos et al., Supervised automated microscopy increases sensitivity and efficiency of detection of sentinel node micrometastases in patients with breast cancer, J. Clin. Pathol. 57 (2004), 960-964.
17. W.E. Mesker, J.M. van de Burg, P.S. Oud et al., Detection of immunocytochemically stained rare events using image analysis, Cytometry 17 (1994), 209-215.
18. J. Mukherjee, M.K. Lang and S.K. Mitra, Demosaicing of images obtained from single-chip imaging sensors in YUV color space, Patt. Recogn. Let. 26 (2005), 985-997.
19. E.R. Nijhuis, N. Reesink-Peters, G.B.A. Wisman et al., An overview of innovative techniques to improve cervical cancer screening, Cell. Oncol. 28 (2006), 233-246.
20. J.C. Oosterwijk, C.F. Knepfle, W.E. Mesker et al., Strategies for rare-event detection: an approach for automated fetal cell detection in maternal blood, Am. J. Hum. Genet. 63 (1998), 1783-1792.
21. A.C. Ruifrok and D.A. Johnston, Quantification of histochemical staining by color deconvolution, Anal. Quant. Cytol. Histol. 23 (2001), 291-299.
22. S. Sahebali, C.E. Depuydt, G.A. Boulet et al., Immunocytochemistry in liquid-based cervical cytology: analysis of clinical use following a cross-sectional study, Int. J. Cancer 118 (2006), 1254-1260.
23. H.J. Tanke, R.J. Florijn, J.Wiegant et al., CCD microscopy and image analysis of cells and chromosomes stained by fluorescence in situ hybridization, Histochem. J. 27 (1995), 4-14.
24. H.J. Tanke, J.C. Oosterwijk, W.E. Mesker et al., Detection of 'rare event' fetal erythroblasts in maternal blood using automated microscopy, Early Hum. Dev. 47(Suppl.) (1996), S89-S93.
25. M.J. Trunk, G. Dallenbach-Hellweg, R. Ridder et al., Morphologic characteristics of p16INK4a-positive cells in cervical cytology samples, Acta Cytol. 48 (2004), 771-782.
26. J.A. van der Laak, M.M. Pahlplatz, A.G. Hanselaar et al., Huesaturation-density (HSD) model for stain recognition in digital images from transmitted light microscopy, Cytometry 39 (2000), 275-284.
27. M. von Knebel-Doeberitz, New markers for cervical dysplasia to visualise the genomic chaos created by aberrant oncogenic papillomavirus infections, Eur. J. Cancer 38 (2002), 2229-2242.