The structures of pyruvate oxidase from Aerococcus viridans with cofactors and with a reaction intermediate reveal the flexibility of the active-site tunnel for catalysis

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 63, Issue 11, 2007, Pages 900-907

  Juan, Ella Czarina Magat ^a,d   Hoque, Md Mominul ^a   Hossain, Md Tofazzal ^a,e   Yamamoto, Tamotsu ^b   Imamura, Shigeyuki ^b   Suzuki, Kaoru ^c   Sekiguchi, Takeshi ^c   Takénaka, Akio ^a  

^a TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^b ASAHI KASEI PHARMA CORPORATION   (Japan)

^c IWAKI MEISEI UNIVERSITY   (Japan)

^d UNIVERSITY OF TOKYO   (Japan)

^e UNIVERSITY OF RAJSHAHI   (Bangladesh)

Author keywords

2 acetyl thiamine diphosphate; Aerococcus viridans; Flavin dinucleotide; Pyruvate oxidase; Thiamine diphosphate

Indexed keywords

2 ACETYLTHIAMINE PYROPHOSPHATE; 2-ACETYLTHIAMINE PYROPHOSPHATE; COCARBOXYLASE; DRUG DERIVATIVE; FLAVINE ADENINE NUCLEOTIDE; PYRUVATE OXIDASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING SITE; CATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; CRYSTALLIZATION; ENZYMOLOGY; STREPTOCOCCACEAE; X RAY CRYSTALLOGRAPHY;

BINDING SITES; CATALYSIS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; FLAVIN-ADENINE DINUCLEOTIDE; MODELS, MOLECULAR; MOLECULAR CONFORMATION; PYRUVATE OXIDASE; STREPTOCOCCACEAE; THIAMINE PYROPHOSPHATE;

AEROCOCCUS VIRIDANS;

EID: 36248969207     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309107041012     Document Type: Article

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