Cutaneous mononuclear cells and eosinophils are significantly increased after warm water challenge in pruritic areas of polycythemia vera

Journal of Cutaneous Pathology

Volumn 34, Issue 12, 2007, Pages 924-929

  Abdel Naser, Mohamed Badawy ^a,b   Zaki, Marwa S ^a   Mousa, Manal H ^a   Hamed, Hanan ^a   Rizk, Mohamed S ^a   Mohamed, Hossam E ^a   Habib, Mohamed A ^a  

^a Ain Shams University   (Egypt)

^b 4 Al Rahman Tower ^*  (Egypt)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; HOT WATER;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DERMIS; DIGITAL IMAGING; EDEMA; EOSINOPHIL; EPIDERMIS; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMAGE ANALYSIS; MALE; MAST CELL; MONONUCLEAR CELL; POLYCYTHEMIA VERA; PROVOCATION TEST; PRURITUS; PUNCH BIOPSY; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; ROOM TEMPERATURE; SKIN BIOPSY; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME; WATER TEMPERATURE;

EOSINOPHILS; FEMALE; HEAT; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LEUKOCYTES, MONONUCLEAR; MALE; MAST CELLS; POLYCYTHEMIA VERA; PRURITUS; SKIN; WATER;

EID: 36248959237     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2007.00927.x     Document Type: Article

References (26)

1. Diehn F, Tefferi A : Pruritus in polycythaemia vera: prevalence, laboratory correlates and management. Br J Hematol 2001 115 : 619.
2. Abdel-Naser MB, Gollnick H, Orfanos CE. Aquagenic pruritus as a presenting symptom of polycythemia vera. Dermatology 1993 187 : 130.
3. Gerlini G, Prignano F, Pimpinelli N. Acute leucocytoclastic vasculitis and aquagenic pruritus long preceding polycythemia rubra vera. Eur J Dermatol 2002 12 : 270.
4. Madkan VK, Bandow GD, Koo JY. Resolution of pruritus secondary to polycythemia vera in a patient treated with narrow-band ultraviolet B phototherapy. J Dermatolog Treat 2005 16 : 56.
5. Baxter DL, Lockwood JH. Acne urticata polycythemica; report of a case. AMA Arch Derm 1958 78 : 325.
6. McMullin MF, Bareford D, Campbell P, et al. Guidelines for the diagnosis, investigation and management of polycythaemia/erythrocytosis. Br J Hematol 2005 130 : 174.
7. Gruppo Italiano Studio Policitemia. Polycythemia vera: the natural history of 1213 patients followed for 20 years. Ann Intern Med 1995 123 : 656.
8. Chaiter Y, Brenner B, Aghai E, Tatarsky I. High incidence of myeloproliferative disorders in Ashkenazi Jews in northern Israel. Leuk Lymphoma 1992 7 : 251.
9. Elder DE, Elenitsas R, Johnson BL Jr., Murphy GF. Histology of the skin. In Elder DE, Elenitsas R, Johnson BL Jr., Murphy GF, eds. Lever's histopathology of skin. 9th edn. Philadelphia : Lippincott, Williams & Wilkins, 2005 45.
10. Requena L, Kutzner H. Invisible dermatosis. Pathologe 2002 23 : 54.
11. Wardlaw AJ. Matrix proteins and eosinophil mediator release. Clin Exp Allergy 2000 30 : 753.
12. Jackson N, Burt D, Crocker J, Boughton B. Skin mast cells in polycythemia vera: Relationship to the pathogenesis and treatment of pruritus. Br J Dermatol 1987 116 : 21.
13. Buchanan JG, Ameratunga RV, Hawkins RC. Polycythemia vera and water-induced pruritus: evidence against mast cell involvement. Pathology 1994 26 : 43.
14. Rivard J, Lim HW. Ultraviolet phototherapy for pruritus. Dermatol Ther 2005 18 : 344.
15. Tinegate H, McLelland J : Trans-cutaneous electrical nerve stimulation may improve pruritus associated with hematological disorders. Clin Lab Hematol 2002 24 : 389.
16. Tefferi A, Fonseca R : Selective serotonin reuptake inhibitors are effective in the treatment of polycythemia vera-associated pruritus. Blood 2002 99 : 2627.
17. Weick JK, Donovan PB, Najean Y, et al. The use of cimetidine for the treatment of pruritus in polycythemia vera. Arch Intern Med 1982 142 : 241.
18. Fitzsimons EJ, Dagg JH, McAllister EJ. Pruritus of polycythemia vera: a place for pizotifen? Br Med J 1981 283 : 277.
19. Fjellner B, Hagermark O. Pruritus in polycythemia vera: treatment with aspirin und possibility of platelet involvement. Acta Derm Venereol 1979 59 : 505.
20. Finelli C, Gugliotta L, Gamberi B, Vianelli N, Visani G, Tura S. Relief of intractable pruritus in polycythemia vera with recombinant interferon alfa. Am J Hematol 1993 43 : 316.
21. Muller EW, de Wolf JT, Egger R, et al. Long-term treatment with interferon-alpha 2b for severe pruritus in patients with polycythaemia vera. Br J Hematol 1995 89 : 313.
22. Greaves MW. Pruritus. In Burns T, Breathnach S, Cox N, Griffiths C, eds. Textbook of Dermatology, 7th edn. Oxford : Blackwell Publishing, 2004 16.
23. Boughton BJ, Allington MJ, King A. Platelet and plasma beta-thromboglobulin in myeloproliferative syndromes and secondary thrombocytosis. Brit J Hematol 1978 40 : 125.
24. Rukwied R, Lischetzki G, McGlone F, Heyer G, Schmelz M. Mast cell mediators other than histamine induce pruritus in atopic dermatitis patients: a dermal microdialysis study. Br J Dermatol 2000 142 : 1114.
25. Xifra A, Carrascosa JM, Ferrandiz C. Narrow-band ultraviolet B in aquagenic pruritus. Br J Dermatol 2005 153 : 1233.
26. Baldo A, Sammarco E, Plaitano R, Martinelli V., Monfrecola. Narrowband (TL-01) ultraviolet B phototherapy for pruritus in polycythaemia vera. Br J Dermatol 2002 147 : 979.