Enhancement of GABA release through endogenous activation of axonal GABAA receptors in juvenile cerebellum

Journal of Neuroscience

Volumn 27, Issue 46, 2007, Pages 12452-12463

  Trigo, Federico F ^a   Chat, Mireille ^a   Marty, Alain ^a  

^a CNRS   (France)

Author keywords

Cerebellum; GABA; GABAA receptor; Molecular layer interneuron; Presynaptic receptor; Synaptic terminal

Indexed keywords

1 [2 (BENZHYDRYLIDENEAMINOOXY)ETHYL] 1,2,5,6 TETRAHYDRO 3 PYRIDINECARBOXYLIC ACID; 3 AMINO 2 (3 CARBOXYPROPYL) 6 (4 METHOXYPHENYL)PYRIDAZINIUM BROMIDE; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID A RECEPTOR; 4 AMINOBUTYRIC ACID A RECEPTOR BLOCKING AGENT; 4 AMINOBUTYRIC ACID A RECEPTOR STIMULATING AGENT; BENZODIAZEPINE; ZOLPIDEM;

4 AMINOBUTYRIC ACID RELEASE; AGE DISTRIBUTION; ANIMAL TISSUE; ARTICLE; BINDING SITE; BRAIN MATURATION; CEREBELLUM; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROSTIMULATION; IMMUNOHISTOCHEMISTRY; INTERNEURON; JUVENILE; MEMBRANE CURRENT; MINIATURE ENDPLATE POTENTIAL; NERVE FIBER; NEWBORN; NONHUMAN; PERINATAL PERIOD; POSITIVE FEEDBACK; PRESYNAPTIC NERVE; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE; SYNAPTIC TRANSMISSION;

ANIMALS; ANIMALS, NEWBORN; AXONS; CEREBELLUM; GABA-A RECEPTOR AGONISTS; GABA-A RECEPTOR ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; INHIBITORY POSTSYNAPTIC POTENTIALS; INTERNEURONS; NEURAL INHIBITION; NEURAL PATHWAYS; ORGAN CULTURE TECHNIQUES; PRESYNAPTIC TERMINALS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SYNAPTIC TRANSMISSION;

EID: 36248952207     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3413-07.2007     Document Type: Article

References (39)

1. Alle H, Geiger JR (2007) GABAergic spill-over transmission onto hippocampal mossy fiber boutons. J Neurosci 27:942-950.
2. Auger C, Marty A (1997) Heterogeneity of functional synaptic parameters among single release sites. Neuron 19:139-150.
3. Auger C, Kondo S, Marty A (1998) Multivesicular release at single functional synaptic sites in cerebellar stellate and basket cells. J Neurosci 18:4532-4547.
4. Awatramani GB, Price GD, Trussell LO (2005) Modulation of transmitter release by presynaptic resting potential and background calcium levels. Neuron 48:109-121.
5. Axmacher N, Draguhn A (2004) Inhibition of GABA release by presynaptic ionotropic GABA receptors in hippocampal CA3. NeuroReport 15:329-334.
6. Brickley SG, Revilla V, Cull-Candy SG, Farrant M (2001) Adaptive regulation of neuronal excitability by a voltage-independent potassium conductance. Nature 409:88-92.
7. Chavas J, Marty A (2003) Coexistence of excitatory and inhibitory GABA synapses in the cerebellar interneuron network. J Neurosci 23:2019-2031.
8. Chavas J, Forero ME, Collin T, Llano I, Marty A (2004) Osmotic tension as a possible link between GABA(A) receptor activation and intracellular calcium elevation. Neuron 44:701-713.
9. Diana MA, Marty A (2003) Characterization of depolarization-induced suppression of inhibition using paired interneuron-Purkinje cell recordings. J Neurosci 23:5906-5918.
10. Farrant M, Nusser Z (2005) Variations on an inhibitory theme: phasic and tonic activation of GABA(A) receptors. Nat Rev Neurosci 6:215-229.
11. Franck CA, Kennedy MJ, Goold CP, Marek KW, Davis GW (2006) Mechanisms underlying the rapid induction and sustained expression of synaptic homeostasis. Neuron 52:663-677.
12. Glitsch M, Marty A (1999) Presynaptic effects of NMDA in cerebellar Purkinje cells and interneurons. J Neurosci 19:511-519.
13. Glykys J, Peng Z, Chandra D, Homanics GE, Houser CR, Mody I (2007) A new naturally occurring GABA(A) receptor subunit partnership with high sensitivity to ethanol. Nat Neurosci 10:40-48.
14. Kondo S, Marty A (1998) Synaptic currents at individual connections among stellate cells in rat cerebellar slices. J Physiol (Lond) 509:221-232.
15. A receptors in the CNS: where and why? Prog Biophys Mol Biol 87:33-46.
16. Llano I, Gerschenfeld HM (1993) Inhibitory synaptic currents in stellate cells of rat cerebellar slices. J Physiol (Lond) 468:177-200.
17. A receptors. Mol Pharmacol 67:775-788.
18. Mann-Metzer P, Yarom Y (2002) Pre- and postsynaptic inhibition mediated by GABA(B) receptors in cerebellar inhibitory interneurons. J Neurophysiol 87:183-190.
19. Mejia-Gervacio S, Marty A (2006) Control of interneurone firing pattern by axonal autoreceptors in the juvenile rat cerebellum. J Physiol (Lond) 571:43-55.
20. Mejia-Gervacio S, Collin T, Pouzat C, Tan Y, Llano I, Marty A (2007) Axonal speeding: shaping synaptic potentials in small neurons by the axonal membrane compartment. Neuron 53:843-855.
21. A receptors on rat hippocampal pyramidal neurons. J Physiol (Lond) 577:841- 856.
22. Nakamura M, Sekino Y, Manabe T (2007) GABAergic interneurons facilitate mossy fiber excitability in the developing hippocampus. J Neurosci 17:1365-1373.
23. A receptor number underlie variation in GABA mini amplitude. Neuron 19:697-709.
24. Nusser Z, Naylor D, Mody I (2001) Synapse-specific contribution of the variation of transmitter concentration to the decay of inhibitory postsynaptic currents. Biophys J 80:1251-1261.
25. A receptors: immunocytochemical distribution of 13 subunits in the adult rat brain. Neuroscience 101:815-850.
26. Pouzat C, Hestrin S (1997) Developmental regulation of basket/stellate cell→Purkinje cell synapses in the cerebellum. J Neurosci 17:9104-9112.
27. Pouzat C, Marty A (1999) Somatic recording of GABAergic autoreceptor current in cerebellar stellate and basket cells. J Neurosci 19:1675-1690.
28. Price GD, Trussell LO (2006) Estimate of the chloride concentration in a central glutamatergic terminal: a gramicidin perforated-patch study on the calyx of Held. J Neurosci 26:11432-11436.
29. A receptors at hippocampal mossy fibers. Neuron 39:961-973.
30. Soudijn W, van Wijngaarden I (2000) The GABA transporter and its inhibitors. Curr Med Chem 7:1063-1079.
31. A conductances in hippocampal neurons. J Neurosci 22:RC223(1-5).
32. Szabadics J, Varga C, Molnar G, Olah S, Barzo P, Tamas G (2006) Excitatory effects of GABAergic axo-axonic cells in cortical microcircuits. Science 311:233-235.
33. Takayama C, Inoue Y (2005) Developmental expression of GABA transporter-1 and 3 during formation of the GABAergic synapses in the mouse cerebellar cortex. Dev Brain Res 158:41-49.
34. Turecek R, Trussell LO (2001) Presynaptic glycine receptors enhance tranmitter release at a mammalian central synapse. Nature 411:587-590.
35. Turecek R, Trussell LO (2002) Reciprocal developmental regulation of presynaptic ionotropic receptors. Proc Natl Acad Sci USA 99:13884-13889.
36. A receptor α1 subunit deletion prevents developmental changes of inhibitory synaptic currents in cerebellar neurons. J Neurosci 9:3009-3016.
37. A receptors facilitate GABAergic transmission to dopaminergic neurons in the ventral tegmental area of young rats. J Physiol (Lond) 580:731-743.
38. Ye J-H, Wang F, Krnjevic K, Wang W, Xiong Z-G, Zhang J (2004) Presynaptic glycine receptors on GABAergic terminals facilitate dicharge of dopaminergic neurons in ventral tegmental area. J Neurosci 24:8961-8974.
39. Zhang SJ, Jackson MB (1993) GABA-activated chloride channels in secretory nerve endings. Science 259:531-534.