Preservation of influenza virosome structure and function during freeze-drying and storage

Journal of Liposome Research

Volumn 17, Issue 3-4, 2007, Pages 173-182

  Wilschut, Jan ^a   De Jonge, Jørgen ^a   Huckriede, Anke ^a   Amorij, Jean Pierre ^b   Hinrichs, Wouter L J ^b   Frijlink, Henderik W ^b  

^a UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^b UNIVERSITY OF GRONINGEN   (Netherlands)

Author keywords

DNA delivery; Stabilization; Sugar glass; Vaccine; Virosomes

Indexed keywords

VIROSOME;

ANIMAL CELL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG STABILITY; FREEZE DRYING; IMMUNOGENICITY; INFLUENZA VIRUS; MEMBRANE FUSION; NONHUMAN; PRIORITY JOURNAL; STORAGE;

ANIMALS; CELL LINE; CRICETINAE; FREEZE DRYING; GENES, REPORTER; LIPOSOMES; ORTHOMYXOVIRIDAE;

EID: 36248946722     PISSN: 08982104     EISSN: 15322394     Source Type: Journal    
DOI: 10.1080/08982100701536883     Document Type: Conference Paper

References (35)

1. Allison, S. D., Molina, M. C., Anchordoquy, T. J. (2000). Stabilization of lipid/DNA complexes during the freezing step of the lyophilization process: the particle isolation hypothesis. Biochim. Biophys. Acta 1468:127-138.
2. Almeida, J. D., Edwards, D. C., et al. (1975). Formation of virosomes from influenza subunits and liposomes. Lancet 2:899-901.
3. Arkema, A., Huckriede, A., et al. (2000). Induction of cytotoxic T lymphocyte activity by fusionactive peptide-containing virosomes. Vaccine 18:1327-1333.
4. Bron, R., Ortiz, A., Wilschut, J. (1994). Cellular cytoplasmic delivery of a polypeptide toxin by reconstituted influenza virus envelopes (virosomes). Biochemistry 33:9110-9117.
5. Bungener, L., de Mare, A., et al. (2006). A virosomal immunization strategy against cervical cancer and pre-malignant cervical disease. Antivir. Ther. 11:717-727.
6. Bungener, L., Huckriede, A., et al. (2005). Virosome-mediated delivery of protein antigens in vivo: efficient induction of class I MHC-restricted cytotoxic T lymphocyte activity. Vaccine 23:1232-1241.
7. Bungener, L., Serre, K., et al. (2002). Virosome-mediated delivery of protein antigens to dendritic cells. Vaccine 20:2287-2295.
8. Carpenter, J. F. Crowe, J. H. (1989). An infrared spectroscopic study of the interactions of carbohydrates with dried proteins. Biochemistry 28:3916-3922.
9. Crowe, J. H., Carpenter, J. F., Crowe, L. M. (1998). The role of vitrification in anhydrobiosis. Annu. Rev. Physiol. 60:73-103.
10. Crowe, J. H., Crowe, L. M., et al. (1988). Interactions of sugars with membranes. Biochim. Biophys. Acta 947:367-384.
11. de Bruijn, I. A., Nauta, J., et al. (2005). Clinical experience with inactivated, virosomal influenza vaccine. Vaccine 23 Suppl 1:S39-S49.
12. de Bruijn, I. A., Nauta, J., et al. (2006). The virosomal influenza vaccine Invivac: immunogenicity and tolerability compared to an adjuvanted influenza vaccine (Fluad) in elderly subjects. Vaccine 24:6629-6631.
13. de Jonge, J., Amorij, J. P., Hinrichs, W. L., Wilschut, J. C., Huckriede, A. L. W., Frijlink, H. W. (2007a). Inulin sugar glasses preserve the structural integrity and biological activity of influenza virosomes during freeze-drying and storage. European Journal of Pharmaceutical Sciences, 32:33-44.
14. de Jonge, J., Holtrop, M., et al. (2006a). Reconstituted influenza virus envelopes as an efficient carrier system for cellular delivery of small-interfering RNAs. Gene Ther. 13:400-411.
15. de Jonge, J., Leenhouts, J. M., et al. (2007b). Cellular gene transfer mediated by influenza virosomes with encapsulated plasmid DNA. Biochem. J. 405:41-49.
16. de Jonge, J., Schoen, P., et al. (2006b). Use of a dialyzable short-chain phospholipid for efficient solubilization and reconstitution of influenza virus envelopes. Biochim. Biophys. Acta. 1758:527-536.
17. Earp, L. J., Delos, S. E., et al. (2005). The many mechanisms of viral membrane fusion proteins. Curr. Top. Microbiol. Immunol. 285:25-66.
18. Hincha, D. K., Zuther, E., et al. (2002). Specific effects of fructo- and gluco-oligosaccharides in the preservation of liposomes during drying. Glycobiology 12:103-110.
19. Hinrichs, W. L., Mancenido, F. A., et al. (2006). The choice of a suitable oligosaccharide to prevent aggregation of PEGylated nanoparticles during freeze thawing and freeze drying. Int. J. Pharm. 311:237-244.
20. Hinrichs, W. L., Prinsen, M. G., Frijlink, H. W. (2001). Inulin glasses for the stabilization of therapeutic proteins. Int. J. Pharm. 215:163-174.
21. Hinrichs, W. L., Sanders, N. N., et al. (2005). Inulin is a promising cryo- and lyoprotectant for PEGylated lipoplexes. J. Control Release 103:465-479.
22. Huckriede, A., Bungener, L., et al. (2003). Influenza virosomes: combining optimal presentation of hemagglutinin with immunopotentiating activity. Vaccine 21:925-931.
23. Huckriede, A., Bungener, L., et al. (2005). The virosome concept for influenza vaccines. Vaccine 23 Suppl 1:S26-S38.
24. Huckriede, A., de Jonge, J., et al. (2007). Cellular delivery of siRNA mediated by fusion-active virosomes. J. Liposome Res. 17:39-47.
25. Li, B., Li, S., et al. (2000). Lyophilization of cationic lipid-protamine-DNA (LPD) complexes. J. Pharm. Sci. 89:355-364.
26. Molina, M. C., Armstrong, T. K., et al. (2004). The stability of lyophilized lipid/DNA complexes during prolonged storage. J. Pharm. Sci. 93:2259-2273.
27. Schoen, P., Bron, R., Wilschut, J. (1993). Delivery of foreign substances to cells mediated by fusion-active reconstituted influenza virus envelopes (virosomes). J. Liposome Res. 3:767-792.
28. Schoen, P., Chonn, A., et al. (1999). Gene transfer mediated by fusion protein hemagglutinin reconstituted in cationic lipid vesicles. Gene Ther. 6:823-832.
29. Stegmann, T., Morselt, H. W., et al. (1987). Fusion of influenza virus in an intracellular acidic compartment measured by fluorescence dequenching. Biochim. Biophys. Acta 904:165-170.
30. Stegmann, T., Schoen, P., et al. (1993). Evaluation of viral membrane fusion assays. Comparison of the octadecylrhodamine dequenching assay with the pyrene excimer assay. Biochemistry 32:11330-11337.
31. Vereyken, I. J., Chupin, V., et al. (2003). The effect of fructan on membrane lipid organization and dynamics in the dry state. Biophys. J. 84:3759-3766.
32. Wang, W. (1999). Instability, stabilization, and formulation of liquid protein pharmaceuticals. Int. J. Pharm. 185:129-188.
33. Wang, W. (2000). Lyophilization and development of solid protein pharmaceuticals. Int. J. Pharm. 203:1-60.
34. Wolfe, J. and Bryant, G. (1999). Freezing, drying, and/or vitrification of membrane- solute-water systems. Cryobiology 39:103-129.
35. Yannarell, D. A., Goldberg, K. M., Hjorth, R. N. (2002). Stabilizing cold-adapted influenza virus vaccine under various storage conditions. J. Virol. Methods 102:15-25.