-
1
-
-
2542481724
-
Phase I study of bortezomib in refractory or relapsed acute leukemias
-
Cortes J., Thomas D., Koller C., et al. Phase I study of bortezomib in refractory or relapsed acute leukemias. Clin Cancer Res 10 (2004) 3371-3376
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3371-3376
-
-
Cortes, J.1
Thomas, D.2
Koller, C.3
-
2
-
-
26844452967
-
Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy
-
Boccadoro M., Morgan G., and Cavenagh J. Preclinical evaluation of the proteasome inhibitor bortezomib in cancer therapy. Cancer Cell Int 5 (2005) 18-26
-
(2005)
Cancer Cell Int
, vol.5
, pp. 18-26
-
-
Boccadoro, M.1
Morgan, G.2
Cavenagh, J.3
-
3
-
-
0034709458
-
NF-kappaB activation is related to the resistance of lung cancer cells to TNF-alpha-induced apoptosis
-
Kim J.Y., Lee S., Hwangbo B., et al. NF-kappaB activation is related to the resistance of lung cancer cells to TNF-alpha-induced apoptosis. Biochem Biophys Res Commun 273 (2000) 140-146
-
(2000)
Biochem Biophys Res Commun
, vol.273
, pp. 140-146
-
-
Kim, J.Y.1
Lee, S.2
Hwangbo, B.3
-
4
-
-
0034092559
-
Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells
-
Kordes U., Krappmann D., Heissmeyer V., Ludwig W.D., and Scheidereit C. Transcription factor NF-kappaB is constitutively activated in acute lymphoblastic leukemia cells. Leukemia 14 (2000) 399-402
-
(2000)
Leukemia
, vol.14
, pp. 399-402
-
-
Kordes, U.1
Krappmann, D.2
Heissmeyer, V.3
Ludwig, W.D.4
Scheidereit, C.5
-
5
-
-
20244377844
-
Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression
-
Komura E., Tonetti C., Penard-Lacronique V., et al. Role for the nuclear factor kappaB pathway in transforming growth factor-beta1 production in idiopathic myelofibrosis: possible relationship with FK506 binding protein 51 overexpression. Cancer Res 65 (2005) 3281-3289
-
(2005)
Cancer Res
, vol.65
, pp. 3281-3289
-
-
Komura, E.1
Tonetti, C.2
Penard-Lacronique, V.3
-
6
-
-
0029859423
-
Current perspective in agnogenic myeloid metaplasia
-
Tefferi A., and Silverstein M.N. Current perspective in agnogenic myeloid metaplasia. Leuk Lymphoma 22 Suppl. 1 (1996) 169-171
-
(1996)
Leuk Lymphoma
, vol.22
, Issue.SUPPL. 1
, pp. 169-171
-
-
Tefferi, A.1
Silverstein, M.N.2
-
7
-
-
0022901242
-
Multilineage expression of haemopoietic precursors with an abnormal clone in idiopathic myelofibrosis
-
Sato Y., Suda T., Suda J., et al. Multilineage expression of haemopoietic precursors with an abnormal clone in idiopathic myelofibrosis. Br J Haematol 64 (1986) 657-667
-
(1986)
Br J Haematol
, vol.64
, pp. 657-667
-
-
Sato, Y.1
Suda, T.2
Suda, J.3
-
8
-
-
0029417041
-
TGF-beta and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders
-
Martyre' M.C. TGF-beta and megakaryocytes in the pathogenesis of myelofibrosis in myeloproliferative disorders. Leuk Lymphoma 20 (1995) 39-44
-
(1995)
Leuk Lymphoma
, vol.20
, pp. 39-44
-
-
Martyre', M.C.1
-
9
-
-
0029970612
-
Implication of CD44 in adhesion-mediated overproduction of TGF-beta and IL-1 in monocytes from patients with bone marrow fibrosis
-
Rameshwar P., Chang V.T., and Gascon P. Implication of CD44 in adhesion-mediated overproduction of TGF-beta and IL-1 in monocytes from patients with bone marrow fibrosis. Br J Haematol 93 (1996) 22-29
-
(1996)
Br J Haematol
, vol.93
, pp. 22-29
-
-
Rameshwar, P.1
Chang, V.T.2
Gascon, P.3
-
10
-
-
0034663758
-
NF-kappa B as a central mediator in the induction of TGF-beta in monocytes from patients with idiopathic myelofibrosis: an inflammatory response beyond the realm of homeostasis
-
Rameshwar P., Narayanan R., Qian J., Denny T.N., Colon C., and Gascon P. NF-kappa B as a central mediator in the induction of TGF-beta in monocytes from patients with idiopathic myelofibrosis: an inflammatory response beyond the realm of homeostasis. J Immunol 165 (2000) 2271-2277
-
(2000)
J Immunol
, vol.165
, pp. 2271-2277
-
-
Rameshwar, P.1
Narayanan, R.2
Qian, J.3
Denny, T.N.4
Colon, C.5
Gascon, P.6
-
11
-
-
30844443469
-
Pathogenesis of myelofibrosis with myeloid metaplasia
-
Tefferi A. Pathogenesis of myelofibrosis with myeloid metaplasia. J Clin Oncol 23 (2005) 8520-8530
-
(2005)
J Clin Oncol
, vol.23
, pp. 8520-8530
-
-
Tefferi, A.1
-
13
-
-
0038719671
-
JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells
-
Chauhan D., Li G., Hideshima T., et al. JNK-dependent release of mitochondrial protein, Smac, during apoptosis in multiple myeloma (MM) cells. J Biol Chem 278 (2003) 17593-17596
-
(2003)
J Biol Chem
, vol.278
, pp. 17593-17596
-
-
Chauhan, D.1
Li, G.2
Hideshima, T.3
-
14
-
-
0142025122
-
Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells
-
Chauhan D., Li G., Sattler M., et al. Superoxide-dependent and -independent mitochondrial signaling during apoptosis in multiple myeloma cells. Oncogene 22 (2003) 6296-6300
-
(2003)
Oncogene
, vol.22
, pp. 6296-6300
-
-
Chauhan, D.1
Li, G.2
Sattler, M.3
-
15
-
-
0037443551
-
The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications
-
Mitsiades N., Mitsiades C.S., Richardson P.G., et al. The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications. Blood 101 (2003) 2377-2380
-
(2003)
Blood
, vol.101
, pp. 2377-2380
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
-
16
-
-
1642486367
-
Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling
-
Yang Y., Ikezoe T., Saito T., Kobayashi M., Koeffler H.P., and Taguchi H. Proteasome inhibitor PS-341 induces growth arrest and apoptosis of non-small cell lung cancer cells via the JNK/c-Jun/AP-1 signaling. Cancer Sci 95 (2004) 176-180
-
(2004)
Cancer Sci
, vol.95
, pp. 176-180
-
-
Yang, Y.1
Ikezoe, T.2
Saito, T.3
Kobayashi, M.4
Koeffler, H.P.5
Taguchi, H.6
-
17
-
-
0032885416
-
The proteasome inhibitor PS-341 in cancer therapy
-
Teicher B.A., Ara G., Herbst R., Palombella V.J., and Adams J. The proteasome inhibitor PS-341 in cancer therapy. Clin Cancer Res 5 (1999) 2638-2645
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2638-2645
-
-
Teicher, B.A.1
Ara, G.2
Herbst, R.3
Palombella, V.J.4
Adams, J.5
-
18
-
-
3042577683
-
Approval summary for bortezomib for injection in the treatment of multiple myeloma
-
Bross P.F., Kane R., Farrell A.T., et al. Approval summary for bortezomib for injection in the treatment of multiple myeloma. Clin Cancer Res 10 (2004) 3954-3964
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3954-3964
-
-
Bross, P.F.1
Kane, R.2
Farrell, A.T.3
-
19
-
-
0037394104
-
Carboxy-terminal fragment of osteogeneic growth peptide in vitro increases bone marrow cell density in idiopathic myelofibrosis
-
Fazzi R., Pacini S., Testi R., et al. Carboxy-terminal fragment of osteogeneic growth peptide in vitro increases bone marrow cell density in idiopathic myelofibrosis. Br J Haematol 121 (2003) 76-85
-
(2003)
Br J Haematol
, vol.121
, pp. 76-85
-
-
Fazzi, R.1
Pacini, S.2
Testi, R.3
-
20
-
-
0032560070
-
Activation of the wt1 Wilms' tumor suppressor gene by NF-kappaB
-
Dehbi M., Hiscott J., and Pelletier J. Activation of the wt1 Wilms' tumor suppressor gene by NF-kappaB. Oncogene 16 (1998) 2033-2039
-
(1998)
Oncogene
, vol.16
, pp. 2033-2039
-
-
Dehbi, M.1
Hiscott, J.2
Pelletier, J.3
-
21
-
-
0036740821
-
Nuclear factor k B is activated in myelodysplastic bone marrow cells
-
Sanz C., Richard C., Prosper F., and Fernandez-Luna J.L. Nuclear factor k B is activated in myelodysplastic bone marrow cells. Haematologica 87 (2002) 1005-1006
-
(2002)
Haematologica
, vol.87
, pp. 1005-1006
-
-
Sanz, C.1
Richard, C.2
Prosper, F.3
Fernandez-Luna, J.L.4
-
22
-
-
0029071670
-
Evaluation of resistance index of several anticancer agents on parental and resistant P-388 cell lines
-
Testi R., Mattii L., Di Simone D., et al. Evaluation of resistance index of several anticancer agents on parental and resistant P-388 cell lines. Leuk Res 19 (1995) 257-261
-
(1995)
Leuk Res
, vol.19
, pp. 257-261
-
-
Testi, R.1
Mattii, L.2
Di Simone, D.3
-
23
-
-
0742321800
-
Significant co-expression of WT1 and MDR1 genes in acute myeloid leukemia patients at diagnosis
-
Galimberti S., Guerrini F., Carulli G., et al. Significant co-expression of WT1 and MDR1 genes in acute myeloid leukemia patients at diagnosis. Eur J Haematol 72 (2004) 45-51
-
(2004)
Eur J Haematol
, vol.72
, pp. 45-51
-
-
Galimberti, S.1
Guerrini, F.2
Carulli, G.3
-
25
-
-
20044396543
-
Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma
-
Goy A., Younes A., McLaughlin P., et al. Phase II study of proteasome inhibitor bortezomib in relapsed or refractory B-cell non-Hodgkin's lymphoma. J Clin Oncol 23 (2005) 667-675
-
(2005)
J Clin Oncol
, vol.23
, pp. 667-675
-
-
Goy, A.1
Younes, A.2
McLaughlin, P.3
-
26
-
-
0035886024
-
Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells
-
Guzman M.L., Neering S.J., Upchurch D., et al. Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells. Blood 98 (2001) 2301-2307
-
(2001)
Blood
, vol.98
, pp. 2301-2307
-
-
Guzman, M.L.1
Neering, S.J.2
Upchurch, D.3
-
27
-
-
0242493856
-
The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571
-
Yu C., Rahmani M., Conrad D., Subler M., Dent P., and Grant S. The proteasome inhibitor bortezomib interacts synergistically with histone deacetylase inhibitors to induce apoptosis in Bcr/Abl+ cells sensitive and resistant to STI571. Blood 102 (2003) 3765-3774
-
(2003)
Blood
, vol.102
, pp. 3765-3774
-
-
Yu, C.1
Rahmani, M.2
Conrad, D.3
Subler, M.4
Dent, P.5
Grant, S.6
-
28
-
-
25844476814
-
Idiopathic myelofibrosis
-
Barosi G., and Hoffman R. Idiopathic myelofibrosis. Semin Hematol 42 (2005) 248-258
-
(2005)
Semin Hematol
, vol.42
, pp. 248-258
-
-
Barosi, G.1
Hoffman, R.2
-
29
-
-
0034719680
-
The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance
-
Mayo M.W., and Baldwin A.S. The transcription factor NF-kappaB: control of oncogenesis and cancer therapy resistance. Biochim Biophys Acta 1470 (2000) M55-M62
-
(2000)
Biochim Biophys Acta
, vol.1470
-
-
Mayo, M.W.1
Baldwin, A.S.2
-
30
-
-
0036796787
-
Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients
-
Cilloni D., Gottardi E., De Micheli D., et al. Quantitative assessment of WT1 expression by real time quantitative PCR may be a useful tool for monitoring minimal residual disease in acute leukemia patients. Leukemia 16 (2002) 2115-2121
-
(2002)
Leukemia
, vol.16
, pp. 2115-2121
-
-
Cilloni, D.1
Gottardi, E.2
De Micheli, D.3
-
31
-
-
0037370833
-
The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia
-
Ogawa H., Tamaki H., Ikegame K., et al. The usefulness of monitoring WT1 gene transcripts for the prediction and management of relapse following allogeneic stem cell transplantation in acute type leukemia. Blood 101 (2003) 1698-1704
-
(2003)
Blood
, vol.101
, pp. 1698-1704
-
-
Ogawa, H.1
Tamaki, H.2
Ikegame, K.3
-
32
-
-
12344262623
-
Quantitative RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML
-
Na I.K., Kreuzer K.A., Lupberger J., Dorken B., and le Coutre P. Quantitative RT-PCR of Wilms tumor gene transcripts (WT1) for the molecular monitoring of patients with accelerated phase bcr/abl + CML. Leuk Res 29 (2005) 343-345
-
(2005)
Leuk Res
, vol.29
, pp. 343-345
-
-
Na, I.K.1
Kreuzer, K.A.2
Lupberger, J.3
Dorken, B.4
le Coutre, P.5
-
33
-
-
4143119022
-
Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation
-
Cilloni D., Messa F., Gottardi E., et al. Sensitivity to imatinib therapy may be predicted by testing Wilms tumor gene expression and colony growth after a short in vitro incubation. Cancer 101 (2004) 979-988
-
(2004)
Cancer
, vol.101
, pp. 979-988
-
-
Cilloni, D.1
Messa, F.2
Gottardi, E.3
-
34
-
-
36148990521
-
Characterization of differentially expressed genes in CD34+ cells from peripheral blood of idiopathic myelofibrosis patients using microarray analysis
-
Guglielmelli P., Manfredini M., Zini R., et al. Characterization of differentially expressed genes in CD34+ cells from peripheral blood of idiopathic myelofibrosis patients using microarray analysis. Haematologica 90 Suppl. 3 (2005) 245
-
(2005)
Haematologica
, vol.90
, Issue.SUPPL. 3
, pp. 245
-
-
Guglielmelli, P.1
Manfredini, M.2
Zini, R.3
-
35
-
-
18444363955
-
Detection of aberrant gene expression in CD34+ hematopoietic stem cells from patients with agnogenic myeloid metaplasia using oligonucleotide microarrays
-
Jones L.C., Tefferi A., Vuong P.T., Desmond J.C., Hofmann W.K., and Koeffler H.P. Detection of aberrant gene expression in CD34+ hematopoietic stem cells from patients with agnogenic myeloid metaplasia using oligonucleotide microarrays. Stem Cells 23 (2005) 631-637
-
(2005)
Stem Cells
, vol.23
, pp. 631-637
-
-
Jones, L.C.1
Tefferi, A.2
Vuong, P.T.3
Desmond, J.C.4
Hofmann, W.K.5
Koeffler, H.P.6
-
36
-
-
33646388007
-
Tesoriere GJNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways
-
Lauricella M., Emanuele S., D'Anneo A., et al. Tesoriere GJNK and AP-1 mediate apoptosis induced by bortezomib in HepG2 cells via FasL/caspase-8 and mitochondria-dependent pathways. Apoptosis 11 (2006) 607-625
-
(2006)
Apoptosis
, vol.11
, pp. 607-625
-
-
Lauricella, M.1
Emanuele, S.2
D'Anneo, A.3
-
37
-
-
2442549643
-
Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors
-
Zheng B., Georgakis G.V., Li Y., et al. Induction of cell cycle arrest and apoptosis by the proteasome inhibitor PS-341 in Hodgkin disease cell lines is independent of inhibitor of nuclear factor-kappaB mutations or activation of the CD30, CD40, and RANK receptors. Clin Cancer Res 10 (2004) 3207-3215
-
(2004)
Clin Cancer Res
, vol.10
, pp. 3207-3215
-
-
Zheng, B.1
Georgakis, G.V.2
Li, Y.3
|