Reperfusion Seizures: A Manifestation of Cerebral Reperfusion Injury After Administration of Recombinant Tissue Plasminogen Activator for Acute Ischemic Stroke

Journal of Stroke and Cerebrovascular Diseases

Volumn 16, Issue 6, 2007, Pages 273-277

  Hafeez, Faizan ^a   Razzaq, Mohammad A ^b   Levine, Ross L ^b   Ramirez, Mark Allan N ^a  

^a MEDICAL COLLEGE OF OHIO   (United States)

^b University of Wisconsin Health   (United States)

Author keywords

Arrhythmia; cerebral ischemia; epilepsy; plasminogen activators; reperfusion; thrombolytic therapy

Indexed keywords

ALTEPLASE; FOSPHENYTOIN SODIUM; HEPARIN; LORAZEPAM;

AGED; ARTICLE; BRAIN INJURY; BRAIN ISCHEMIA; CASE REPORT; CEREBROVASCULAR ACCIDENT; DYSPHASIA; FIBRINOLYTIC THERAPY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; LOADING DRUG DOSE; MALE; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REPERFUSION INJURY; SEIZURE; WEAKNESS;

AGED; ANTICONVULSANTS; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; ELECTROENCEPHALOGRAPHY; FIBRINOLYTIC AGENTS; HUMANS; INFUSIONS, INTRAVENOUS; LORAZEPAM; MALE; PHENYTOIN; RECOMBINANT PROTEINS; REPERFUSION INJURY; SEIZURES; STROKE; TIME FACTORS; TISSUE PLASMINOGEN ACTIVATOR; TREATMENT OUTCOME;

EID: 36148988327     PISSN: 10523057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jstrokecerebrovasdis.2007.07.007     Document Type: Article

References (20)

1. Sheehan J., and Tsirka S. Fibrin-modifying serine protease thrombin, tPA, and plasmin in ischemic stroke: A review. Glia 50 (2005) 340-350
2. Jeroudi M., Harley C., and Bolli R. Myocardial reperfusion injury: Role of oxygen radicals and potential therapy with antioxidants. Am J Cardiol 73 (1994) 2B-7B
3. Bolli R., and Patel B. Factors that determine the occurrence of reperfusion arrhythmias. Am Heart J 115 (1988) 120
4. Joshua I., Goldhaber W., and Weiss J. Oxygen free radicals and cardiac reperfusion abnormalities. Hypertension 20 (1992) 118-127
5. Bernier M., Hearse D.J., and Manning A.S. Reperfusion-induced arrhythmias and oxygen derived free radicals. Circ Res 58 (1986) 331-340
6. Nayler G.W., Panagiotopuolos L.Z., and Daly M.J. Calcium mediated damage during post-ischemic reperfusion. J Mol Cell Cardiol 20 suppl (1988) 41-54
7. Bassett A.L., Chakko S., and Epstein M. Are calcium antagonists proarrhythmic?. J Hypertension 15 (1997) 915-923
8. Burashnikov A., Medvinski I., and Hkin N.I. The defining role of calcium entering cells during ischemia as the mechanism for initiating reperfusion arrhythmias. [in Russian]. Biofizika 42 (1997) 508-515
9. Woodward B., and Zakaria M.N.M. Effect of some free radical scavengers on reperfusion induced arrhythmias in the isolated rat heart. J Mol Cell Cardiol 17 (1985) 485-493
10. Hearse D.J., Kusama Y., and Bernier M. Rapid electrophysiological changes leading to arrhythmias in the aerobic rat heart: Photosensitization studies with rose bengal-derived reactive oxygen intermediates. Circ Res 65 (1989) 146-153
11. Garlick P.B., Davies M.J., Hearse D.J., et al. Direct detection of free radical in the reperfused heart using electron spin resonance spectroscopy. Circ Res 61 (1987) 757-760
12. Pallandi R.T., Perry M.A., and Campbell T.J. Proarrhythmic effects of an oxygen derived free radical generating system on action potentials recorded from guinea pig ventricular myocardium: A possible cause of reperfusion-induced arrhythmias. Circ Res 61 (1987) 50-54
13. Barrington P.L., Meier C.F., and Weglicki W.B. Abnormal electrical activity induced by free radical generating systems in isolated cardiocytes. J Mol Cell Cardiol 20 (1988) 1163-1178
14. Hearse T.J., and Tosaki A. Free radicals and calcium: Simultaneous interacting triggers as determinants of vulnerability to reperfusion-induced arrhythmias in the rat heart. J Mol Cell Cardiol 20 (1988) 213-223
15. Kuroda S., and Siesjo B.K. Reperfusion damage following focal ischemia: Pathophysiology and therapeutic windows. Clin Neurosci 4 (1997) 199-212
16. Francis J.W., Ren J., Warren L., et al. Post ischemic infusion of Cu/Zn superoxide dismutase or SOD:Tet 451 reduces cerebral infarction following ischemia/reperfusion in rats. Exp Neurol 146 (1997) 435-443
17. Toyoda T., Kassell N.F., and Lee K.S. Attenuation of ischemia-reperfusion injury in the rat neocortex by the hydroxy radical scavenger nicaraven. Neurosurgery 40 (1997) 372-377
18. Panigrahi M., Sadguna Y., Shivkumar B.R., et al. Alpha-lipoic acid protects against reperfusion injury following cerebral ischemia in rats. Brain 717 (1996) 184-188
19. Sun G.Y., and Hsu C.Y. Poly-phosphoinositide-mediated messengers in focal cerebral ischemia and reperfusion. J Lipid Mediators Cell Signal 14 (1996) 137-145
20. Tan W.K., Williams C.E., During M.J., et al. Accumulation of cytotoxins during the development of seizures and edema after hypoxic-ishemic injury in late gestation fetal sheep. Pediatr Res 39 (1996) 791-797