Effect of Postmastectomy Radiotherapy in Patients <35 Years Old With Stage II-III Breast Cancer Treated With Doxorubicin-Based Neoadjuvant Chemotherapy and Mastectomy

International Journal of Radiation Oncology Biology Physics

Volumn 69, Issue 5, 2007, Pages 1478-1483

  Garg, Amit K ^a   Oh, Julia L ^a   Oswald, Mary Jane ^a   Huang, Eugene ^a   Strom, Eric A ^a   Perkins, George H ^a   Woodward, Wendy A ^a   Yu, T Kuan ^a   Tereffe, Welela ^a   Meric Bernstam, Funda ^a   Hahn, Karin ^a   Buchholz, Thomas A ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

mastectomy; neoadjuvant chemotherapy; Radiation therapy; young age

Indexed keywords

CHEMOTHERAPY; DISEASES; ONCOLOGY; RISK MANAGEMENT;

BREAST CANCER PATIENTS; MASTECTOMY; NEOADJUVANT CHEMOTHERAPY;

RADIOTHERAPY;

DOXORUBICIN; TAMOXIFEN;

ADULT; ADVANCED CANCER; AGE; ARTICLE; BREAST CANCER; CANCER ADJUVANT THERAPY; CANCER CONTROL; CANCER PATIENT; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DECISION MAKING; FEMALE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MASTECTOMY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; RISK FACTOR; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; AGE FACTORS; BREAST NEOPLASMS; CHEMOTHERAPY, ADJUVANT; DOXORUBICIN; FEMALE; HUMANS; LYMPHATIC METASTASIS; MASTECTOMY; NEOADJUVANT THERAPY; NEOPLASM RECURRENCE, LOCAL; NEOPLASM STAGING; RETROSPECTIVE STUDIES; SURVIVAL ANALYSIS;

EID: 36148958622     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2007.05.029     Document Type: Article

References (22)

1. de la Rochefordiere A., Asselain B., Campana F., et al. Age as prognostic factor in premenopausal breast carcinoma. Lancet 341 (1993) 1039-1043
2. Aebi S., Gelber S., Castiglione-Gertsch M., et al. Is chemotherapy alone adequate for young women with oestrogen-receptor-positive breast cancer?. Lancet 355 (2000) 1869-1874
3. Nixon A.J., Neuberg D., Hayes D.F., et al. Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer. J Clin Oncol 12 (1994) 888-894
4. Albain K.S., Allred D.C., and Clark G.M. Breast cancer outcome and predictors of outcome: Are there age differentials?. J Natl Cancer Inst Monogr 16 (1994) 35-42
5. Agrup M., Stal O., Olsen K., et al. C-erbB-2 overexpression and survival in early onset breast cancer. Breast Cancer Res Treat 63 (2000) 23-29
6. Marcus J.N., Watson P., Page D.L., et al. Pathology and heredity of breast cancer in younger women. J Natl Cancer Inst Monogr 16 (1994) 23-34
7. Matthews R.H., McNeese M.D., Montague E.D., et al. Prognostic implications of age in breast cancer patients treated with tumorectomy and irradiation or with mastectomy. Int J Radiat Oncol Biol Phys 14 (1988) 659-663
8. Oh J.L., Bonnen M., Outlaw E.D., et al. The impact of young age on locoregional recurrence after doxorubicin-based breast conservation therapy in patients 40 years old or younger: How young is "young"?. Int J Radiat Oncol Biol Phys 65 (2006) 1345-1352
9. Nielsen H.M., Overgaard M., Grau C., et al. Study of failure pattern among high-risk breast cancer patients with or without postmastectomy radiotherapy in addition to adjuvant systemic therapy: Long-term results from the Danish Breast Cancer Cooperative Group DBCG 82 b and c randomized studies. J Clin Oncol 24 (2006) 2268-2275
10. Ragaz J., Olivotto I.A., Spinelli J.J., et al. Locoregional radiotherapy in patients with high-risk breast cancer receiving adjuvant chemotherapy: 20-year results of the British Columbia randomized trial. J Natl Cancer Inst 97 (2005) 116-126
11. Clarke M., Collins R., Darby S., et al. Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year survival: An overview of the randomised trials. Lancet 366 (2005) 2087-2106
12. Huang E.H., Tucker S.L., Strom E.A., et al. Postmastectomy radiation improves local-regional control and survival for selected patients with locally advanced breast cancer treated with neoadjuvant chemotherapy and mastectomy. J Clin Oncol 22 (2004) 4691-4699
13. Truong P.T., Olivotto I.A., Kader H.A., et al. Selecting breast cancer patients with T1-T2 tumors and one to three positive axillary nodes at high postmastectomy locoregional recurrence risk for adjuvant radiotherapy. Int J Radiat Oncol Biol Phys 61 (2005) 1337-1347
14. Taghian A., Jeong J.H., Mamounas E., et al. Patterns of locoregional failure in patients with operable breast cancer treated by mastectomy and adjuvant chemotherapy with or without tamoxifen and without radiotherapy: Results from five National Surgical Adjuvant Breast and Bowel Project randomized clinical trials. J Clin Oncol 22 (2004) 4247-4254
15. Fodor J., Polgar C., Major T., et al. Locoregional failure 15 years after mastectomy in women with one to three positive axillary nodes with or without irradiation the significance of tumor size. Strahlenther Onkol 179 (2003) 197-202
16. Garg A.K., Strom E.A., McNeese M.D., et al. T3 disease at presentation or pathologic involvement of four or more lymph nodes predict for locoregional recurrence in stage II breast cancer treated with neoadjuvant chemotherapy and mastectomy without radiotherapy. Int J Radiat Oncol Biol Phys 59 (2004) 138-145
17. Recht A., Gray R., Davidson N.E., et al. Locoregional failure 10 years after mastectomy and adjuvant chemotherapy with or without tamoxifen without irradiation: Experience of the Eastern Cooperative Oncology Group. J Clin Oncol 17 (1999) 1689-1700
18. Voogd A.C., Nielsen M., Peterse J.L., et al. Differences in risk factors for local and distant recurrence after breast-conserving therapy or mastectomy for stage I and II breast cancer: Pooled results of two large European randomized trials. J Clin Oncol 19 (2001) 1688-1697
19. Arriagada R., Le M.G., Contesso G., et al. Predictive factors for local recurrence in 2006 patients with surgically resected small breast cancer. Ann Oncol 13 (2002) 1404-1413
20. Eifel P., Axelson J.A., Costa J., et al. National Institutes of Health Consensus Development Conference Statement: adjuvant therapy for breast cancer, November 1-3, 2000. J Natl Cancer Inst 93 (2001) 979-989
21. Harris J.R., Halpin-Murphy P., McNeese M., et al. Consensus statement on postmastectomy radiation therapy. Int J Radiat Oncol Biol Phys 44 (1999) 989-990
22. Recht A., Edge S.B., Solin L.J., et al. Postmastectomy radiotherapy: Clinical practice guidelines of the American Society of Clinical Oncology. J Clin Oncol 19 (2001) 1539-1569