Antimalarial drug toxicity: A review

Chemotherapy

Volumn 53, Issue 6, 2007, Pages 385-391

  Alkadi, Hussien O ^a  

^a SANA A UNIVERSITY   (Yemen)

Author keywords

Antimalarial drugs; Toxicity

Indexed keywords

AMODIAQUINE; ANTIMALARIAL AGENT; ARTEMETHER; ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTEMISININ DERIVATIVE; ARTESUNATE; ATOVAQUONE; ATOVAQUONE PLUS PROGUANIL; CHLOROQUINE; COTRIMOXAZOLE; DOXYCYCLINE; FANSIDAR; HALOFANTRINE; ISONIAZID; MEFLOQUINE; PIPERAQUINE; PRIMAQUINE; PYRIMETHAMINE; PYRIMETHAMINEDAPSONE; QUININE; QUININE SULFATE; RIFAMPICIN; SULFAMETHOXAZOLE; TRIMETHOPRIM; UNCLASSIFIED DRUG;

ABDOMINAL PAIN; AGRANULOCYTOSIS; AMINOTRANSFERASE BLOOD LEVEL; AMYLASE BLOOD LEVEL; ANOREXIA; ANXIETY; APHTHOUS ULCER; BLINDNESS; BRAIN TOXICITY; CARDIOTOXICITY; CENTRAL NERVOUS SYSTEM DEPRESSION; DEPRESSION; DERMATITIS; DIARRHEA; DIZZINESS; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; DRUG WITHDRAWAL; DYSPHORIA; ERYTHEMA MULTIFORME; ESOPHAGUS ULCER; EYE TOXICITY; FEVER; FOLIC ACID DEFICIENCY; GASTROINTESTINAL SYMPTOM; GASTROINTESTINAL TOXICITY; GRANULOCYTOPENIA; GRANULOCYTOSIS; HALLUCINATION; HEADACHE; HEARING IMPAIRMENT; HEART ARREST; HEART ARRHYTHMIA; HEART DISEASE; HEMATOPOIESIS; HEMOLYSIS; HEMOLYTIC ANEMIA; HEPATITIS; HUMAN; HYPERTENSION; HYPOGLYCEMIA; HYPOTENSION; INSOMNIA; KIDNEY DISEASE; LIVER INJURY; MALARIA; MEGALOBLASTIC ANEMIA; METHEMOGLOBINEMIA; MORTALITY; NAUSEA; NEUROPSYCHIATRIC TOXICITY; NEUROTOXICITY; ORTHOSTATIC HYPOTENSION; PARANOIA; PHYSICIAN; PLASMODIUM FALCIPARUM; PREGNANCY; PRESCRIPTION; PRIORITY JOURNAL; PROPHYLAXIS; PRURITUS; PSYCHOSIS; RASH; REVIEW; RISK; RISK BENEFIT ANALYSIS; SEIZURE; SERUM SICKNESS; SIDE EFFECT; STEVENS JOHNSON SYNDROME; TINNITUS; TOXIC EPIDERMAL NECROLYSIS; UNPLEASANT DREAM; VISUAL DISORDER; VIVID DREAM; VOMITING;

ANIMALS; ANTIMALARIALS; HUMANS;

EID: 36049034897     PISSN: 00093157     EISSN: None     Source Type: Journal    
DOI: 10.1159/000109767     Document Type: Review

References (43)

1. Taylor WR, White NJ: Antimalarial drug toxicity. Drug Saf 2004;27:25-61.
2. Luzzi GA, Peto TE: Adverse effects of antimalarials. An update. Drug Saf 1993;8:295-311.
3. Winstanley P, Ward S, Snow R, Breckenridge A: Therapy of falciparum malaria in Sub-Saharan Africa: from molecule to policy. Clin Microbiol Rev 2004;17:612-637.
4. Pirmohamed M, Breckenridge AM, Kitteringham NR, Park BK: Adverse drug reactions. BMJ 1998;316:1295-1298.
5. Croft AM, Whitehouse DP, Cook GC, Beer MD: Safety evaluation of the drugs available to prevent malaria. Expert Opin Drug Saf 2002;1:19-27.
6. Fehintola FA, Olayemi O, Osungbade K, Tongo O, Olomu SA, Falade CO, Salako BL, Sowunmi A: Profile of chloroquine-induced pruritus in Nigerian children resident in Ibadan, Nigeria. Afr J Biomed Res 2004;3:97-101.
7. Ademowo OG, Sodeinde O: Certain red cell genetic factors and prevalence of chloroquine-induced pruritus. Afr J Med Med Sci 2002,31:341-343.
8. Bacon JF, Shenfield GM: Pregnancy attributable to interaction between tetracycline and oral contraceptives. Br Med J 1980;280:293.
9. Crawley J, Kokwaro G, Ouma D, Watkins W, Marsh K: Chloroquine is not a risk factor for seizures in childhood cerebral malaria. Trop Med Int Health 2000;5:860-864.
10. Hall AH, Kulig KW: Drug- and chemical-induced methaemoglobinaemia. Clinical features and management. Med Toxicol 1986;1:253-260.
11. Tester-Dalderup CBM: Antimalarial drugs; in Dukes MNG: Meyler's Side Effects of Drugs, ed 11. Amsterdam, Elsevier, 1988, pp 581-602.
12. Palmer KJ, Holliday SM, Brogden RN: Mefloquine. A review of its antimalarial activity, pharmacokinetic properties and therapeutic efficacy. Drugs 1993;45:475.
13. Phillips-Howard PA, ter Kuile FO: CNS adverse events associated with antimalarial agents: Fact or fiction? Drug Saf 1995;12:370-383.
14. True RJ: Interactions between antibiotics and oral contraceptives (letter). JAMA 1982;247:1408.
15. Schlagenhauf P: Mefloquine for malaria chemoprophylaxis 1992-1998:a review. J Travel Med 1999;6:122-133.
16. Goerg H, Ochola SA, Goerg R: Treatment of malaria tropica with a fixed combination of rifampicin, co-trimoxazole and isoniazid: a clinical study. Chemotherapy 1999;45:68-76.
17. Robert G. Patterson, Rachel LC: Trimethoprim-sulfamethoxazole-induced tremor in an immunocompetent patient. Pharmacotherapy 1999;19:1456-1458.
18. Floris-Moore MA, Amodio-Groton MI, Catalano MT: Adverse reactions to trimethoprim/ sulfamethoxazole in AIDS. Ann Pharmacother 2003;37:1810-1813.
19. Bateman DN, Blain PG, Woodhouse KW, Rawlins MD, Dyson H, Heyworth R, Prescott LF, Proudfoot AT: Pharmacokinetics and clinical toxicity of quinine overdosage: lack of efficacy of techniques intended to enhance elimination. Q J Med 1985;54:125-131.
20. Bateman DN, Dyson EH: Quinine toxicity. Adverse Drug React Acute Poisoning Rev 1986;5:215-233.
21. Goldenberg AM, Wexler LF: Quinine overdose: review of toxicity and treatment. Clin Cardiol 1988;11:716-718.
22. Ribeiro IR, Olliaro P: Safety of artemisinin and its derivatives. A review of published and unpublished clinical trials. Med Trop (Mars) 1998;58(3 suppl):50-53.
23. Looareesuwan S, Chulay JD, Canfield CJ, Hutchinson DB: Malarone (atovaquone and proguanil hydrochloride): a review of its clinical development for treatment of malaria. Malarone Clinical Trials Study Group. Am J Trop Med Hyg 1999;60:533-541.
24. Yap YG, Camm AJ: Drug induced QT prolongation and torsades de pointes. Heart 2003;89:1363-1372.
25. Bakshi R, Hermeling FI, Gathmann I, Alteri E: An integrated assessment of the clinical safety of artemether-lumefantrine: a new oral fixed-dose combination antimalarial drug. Trans R Soc Trop Med Hyg 2000;94:419-424
26. Bernstein HN: Ophthalmologic considerations and testing in patients receiving long-term antimalarial therapy. Am J Med 1983;75:25-34.
27. Neubauer AS, Samari-Kermani K, Schaller U, Welge-Lüssen U, Rudolph G, Berninger T: Detecting chloroquine retinopathy: electrooculogram versus colour vision. Br J Ophthalmol 2003;87:902-908.
28. Canning CR, Hague S: Ocular quinine toxicity. Br J Opthalmol 1988;72:23-26.
29. Hirst LW, Sanborn G, Green WR, Miller NR, Heath WD: Amodiaquine ocular changes. Arch Ophthalmol 1982;100:1300-1304.
30. Zuckner J: Drug-related myopathies. Rheum Dis Clin North Am 1994;20:1017-1032.
31. Wasay M, Wolfe GI, Herrold JM: Chloroquine myopathy and neuropathy with elevated CSF protein. Neurology 1998;51:1226-1227.
32. Stuiver PC, Ligthelm RJ, Goud TJ: Acute psychosis after mefloquine. Lancet 1989;ii:282.
33. Amabeoku GJ, Chikuni O: GABAergic and dopaminergic systems may be involved in seizures induced by pyrimethamine in mice. Gen Pharmacol 1994;25:1269-1277.
34. Crawley J, Smith S, Kirkham F, Muthinji P, Waruiru C, Marsh K: Seizures and status epilepticus in childhood cerebral malaria. Q J Med 1996;89:591-597.
35. Schonwald S, Shannon M: Unsuspected quinine intoxication presenting as acute deafness and mutism. Am J Emerg Med 1991;9:318-320.
36. Nagarajan L, Lam GC: Tetracycline-induced benign intracranial hypertension. J Paediatr Child Health 2000;36:82-83.
37. Winstanley PA, Coleman JW, Maggs JL, Breckenridge AM, Park BK: The toxicity of amodiaquine and its principal metabolites towards mononuclear leucocytes and granulocyte/ monocyte colony forming units. Br J Clin Pharmacol 1990;29:479-485.
38. Mainra RR, Card SE: Trimethoprim-sulfamethoxazole-associated hepatotoxicity - part of a hypersensitivity syndrome. Can J Clin Pharmacol 2003;10:175-178.
39. Lienart F, Morissens M, Jacobs P, Ducobu J: Doxycycline and hepatotoxicity. Acta Clin Belg 1992;47:205-208.
40. Williams RB: Avian malaria: Clinical and chemical pathology of Plasmodium gallinaceum in the domesticated fowl Gallus gallus. Avian Pathol 2005;34:29-47.
41. Phillips-Howard PA, Steffen R, Kerr L, Vanhauwere B, Schildknecht J, Fuchs E, Edwards R: Safety of mefloquine and other antimalarial agents in the first trimester of pregnancy. J Travel Med 1998;5:121-126.
42. McGready R, Brockman A, Cho T, Cho D, van Vugt M, Luxemburger C, Chongsuphajaisiddhi T, White NJ, Nosten F: Randomized comparison of mefloquine-artesunate versus quinine in the treatment of multidrug-resistant falciparum malaria in pregnancy. Trans R Soc Trop Med Hyg 2000;94:689-693.
43. McGready R, Ashley EA, Moo E, Cho T, Barends M, Hutagalung R, Looareesuwan S, White NJ, Nosten F: A randomized comparison of artesunate-atovaquone-proguanil versus quinine in treatment for uncomplicated falciparum malaria during pregnancy. J Infect Dis 2005;192:846-853.