Sublingual-swallow immunotherapy with standardized 3-grass pollen extract: A double-blind, placebo-controlled study

Annals of Allergy, Asthma and Immunology

Volumn 99, Issue 5, 2007, Pages 453-461

  De Blay, Frédéric ^a   Barnig, Cindy ^a   Kanny, Gisèle ^b   Purohit, Ashok ^a   Leynadier, Francisque ^c   De Lara, J Manuel Tunon ^d   Chabane, Habib ^e   Guérin, Laurence ^e   Auffret, Annick ^f   Basset, Dominique ^f   Cardot, Eric ^f   Croizier, Alain ^f   Hanss, Christophe ^f   Doudou, Oufia ^f   Duarte Risselin, Claudia ^f   Mathelier Fusade, Pascale ^f   Deshayes, Hélène ^f   Faure, Bruno ^f   Laur, Clair ^f   Mollé, Isabelle ^f   Pauli, Gabrielle ^f   Roca, Jean Claude ^f   Zana, Hélène ^f   Aparicio, Christine ^g   Grenapin, Sandrine ^h   Lapeyre, Françoise ^h   Leduc, Virginie ^h   Magnier, Gabrielle ^h   more..

^a UNIVERSITY HOSPITAL OF STRASBOURG   (France)

^b UNIVERSITY HOSPITAL OF NANCY   (France)

^c HÔPITAL TENON   (France)

^d INSERM   (France)

^e Allerbio   (France)

^f Aude Devoitine Quality Department ^*

^g Aude Devoitine Quality Department   (France)

^h Laboratoire Allerbio   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GRASS POLLEN EXTRACT; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G4; PLACEBO;

ABDOMINAL PAIN; ADOLESCENT; ADULT; ALLERGY; ARTICLE; ASTHMA; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DACTYLIS; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; DRUG SAFETY; EDEMA; FEMALE; HEADACHE; HUMAN; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; LIP EDEMA; MAJOR CLINICAL STUDY; MALE; MOUTH DISEASE; MOUTH ULCER; MULTICENTER STUDY; PATIENT COMPLIANCE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RHINOCONJUNCTIVITIS; SCHOOL CHILD; THROAT IRRITATION;

EID: 36049003063     PISSN: 10811206     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1081-1206(10)60571-6     Document Type: Article

References (22)

1. Bousquet J, Van Cauwenberge P, Khaltaev N. Allergic rhinitis and its impact on asthma. J Allergy Clin Immunol. 2001;108(suppl):S147-S334.
2. Settipane RJ, Hagy GW, Settipane GA. Long-term risk factors for developing asthma and allergic rhinitis: a 23-year follow-up study of college students. Allergy Proc. 1994;15:21-25.
3. Wilson DR, Torres LI, Durham SR. Sublingual immunotherapy for allergic rhinitis. Cochrane Database Syst Rev. 2003;2:CD002893.
4. Juniper EF, Thompson AK, Ferrie PJ, Roberts JN. Development and validation of the mini Rhinoconjunctivitis Quality of Life Questionnaire. Clin Exp Allergy. 2000;30:132-140.
5. Malet A, Lluch M, Valero AL, Casanovas M. Clinical and immunological effects of immunotherapy with glutaraldehyde modified house dust mite extract. Allergol Immunopathol. 1994;22:226-232.
6. Malling HJ. Methodology and quality of immunotherapy trials. Allergy. 2004;59:482-484.
7. Khinchi MS, Poulsen LK, Carat F, Andre C, Hansen AB, Malling HJ. Clinical efficacy of sublingual and subcutaneous birch pollen allergen-specific immunotherapy: a randomized, placebo-controlled, double-blind, double-dummy study. Allergy. 2004;59:45-53.
8. Smith H, White P, Annila I, Poole J, Andre C, Frew A. Randomized controlled trial of high-dose sublingual immunotherapy to treat seasonal allergic rhinitis. J Allergy Clin Immunol. 2004;114:831-837.
9. Wilson DR, Irani AM, Walker SM, et al. Grass pollen immunotherapy inhibits seasonal increases in basophils and eosinophils in the nasal epithelium. Clin Exp Allergy. 2001;31:1705-1713.
10. Di Rienzo V, Pagani A, Parmiani S, Passalacqua G, Canonica GW. Post-marketing surveillance study on the safety of sublingual immunotherapy in pediatric patients. Allergy. 1999;54:1110-1113.
11. La Rosa M, Ranno C, Andre C, Carat F, Tosca MA, Canonica GW. Double-blind placebo-controlled evaluation of sublingual-swallow immunotherapy with standardized Parietaria judaica extract in children with allergic rhinoconjunctivitis. J Allergy Clin Immunol. 1999;104(pt 1):425-432.
12. Pradalier A, Basset D, Claudel A, et al. Sublingual-swallow immunotherapy (SLIT) with a standardized five-grass-pollen extract (drops and sublingual tablets) versus placebo in seasonal rhinitis. Allergy. 1999;54:819-828.
13. Clavel R, Bousquet J, Andre C. Clinical efficacy of sublingual-swallow immunotherapy: a double-blind, placebo-controlled trial of a standardized five-grass-pollen extract in rhinitis. Allergy. 1998;53:493-498.
14. Hordijk GJ, Antvelink JB, Luwema RA. Sublingual immunotherapy with a standardised grass pollen extract: a double-blind placebo-controlled study. Allergol Immunopathol (Madr). 1998;26:234-240.
15. Niederberger V, Horak F, Vrtala S, et al. Vaccination with genetically engineered allergens prevents progression of allergic disease. Proc Natl Acad Sci U S A. 2004;101(suppl 2):14,677-14,682.
16. Piazza I, Bizzaro N. Humoral response to subcutaneous, oral, and nasal immunotherapy for allergic rhinitis due to Dermatophagoides pteronyssinus. Ann Allergy. 1993;71:461-469.
17. Lima MT, Wilson D, Pitkin L, et al. Grass pollen sublingual immunotherapy for seasonal rhinoconjunctivitis: a randomized controlled trial. Clin Exp Allergy. 2002;32:507-514.
18. Quirino T, Iemoli E, Siciliani E, Parmiani S, Milazzo F. Sublingual versus injective immunotherapy in grass pollen allergic patients: a double blind (double dummy) study. Clin Exp Allergy. 1996;26:1253-1261.
19. Rolinck-Werninghaus C, Wolf H, Liebke C, et al. A prospective, randomized, double-blind, placebo-controlled multi-centre study on the efficacy and safety of sublingual immunotherapy (SLIT) in children with seasonal allergic rhinoconjunctivitis to grass pollen. Allergy. 2004;59:1285-1293.
20. Lombardi C, Gani F, Landi M, et al. Quantitative assessment of the adherence to sublingual immunotherapy. J Allergy Clin Immunol. 2004;113:1219-1220.
21. Lower T, Henry J, Mandik L, Janosky J, Friday GA Jr. Compliance with allergen immunotherapy. Ann Allergy. 1993;70:480-482.
22. Cohn JR, Pizzi A. Determinants of patient compliance with allergen immunotherapy. J Allergy Clin Immunol. 1993;91:734-737.