Lupus-like reaction to interferon at the injection site: Report of five cases

Journal of Cutaneous Pathology

Volumn 34, Issue SUPPL. 1, 2007, Pages 18-21

  Arrue, Itziar ^a   Saiz, Ana ^a   Ortiz Romero, Pablo Luis ^a   Rodríguez Peralto, José Luis ^a,b  

^a Hospital Univ   (Spain)

^b HOSPITAL UNIVERSITARIO 12 DE OCTUBRE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2B INTERFERON; ANTIBIOTIC AGENT; INTERFERON BETA SERINE; MUCIN; PEGINTERFERON;

ADULT; ARTICLE; CANCER IMMUNOTHERAPY; CELL DENSITY; CLINICAL ARTICLE; DRUG FEVER; DRUG SAFETY; FATIGUE; FEMALE; HAIR FOLLICLE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INJECTION SITE ERYTHEMA; INJECTION SITE PAIN; INJECTION SITE REACTION; INOCULATION; LUPUS LIKE SYNDROME; LYMPH NODE METASTASIS; LYMPHOCYTIC INFILTRATION; MALE; MELANOMA; MULTIPLE SCLEROSIS; SKIN BIOPSY; TISSUE DEGENERATION; TREATMENT OUTCOME;

ADULT; DIAGNOSIS, DIFFERENTIAL; DRUG ERUPTIONS; FEMALE; HUMANS; INJECTIONS, SUBCUTANEOUS; INTERFERON ALFA-2B; INTERFERON-BETA; LUPUS ERYTHEMATOSUS, CUTANEOUS; MALE; MIDDLE AGED; SKIN;

EID: 36048986302     PISSN: 03036987     EISSN: 16000560     Source Type: Journal    
DOI: 10.1111/j.1600-0560.2007.00715.x     Document Type: Article

References (15)

1. Sánchez J, Castillo MJ, García E, Ferrer JA. Lupus eritematoso sistémico inducido por tratamiento con interferón alfarrecombinante. Med Clin 1994 102 : 198.
2. Noussari HC, Kimyai-Asadi A, Tausk FA. Subacute cutaneous lupus erythematous associated with interferon beta-1a. Lancet 1998 352 : 1825.
3. Tolaymat A, Leventhal B, Sakarcan A, Kashima H, Monteiro C. Systemic lupus erythematous in a child receiving long-term interferon therapy. J Pediatr 1992 120 : 429.
4. Chang L, Liranzo M, Bergfeld W. Cutaneous side effects associated with interferon-alfa therapy: a review. Cutis 1995 56 : 144.
5. Montoto S, Bosch F, Estrach T, Blade J, Nomdedeu B, Nontserrat E. Pyoderma gangrenosum triggered by alpha 2b interferon in a patient with chronic granulocytic leukaemia. Leuk Lymphoma 1998 30 : 199.
6. Klapholz L, Ackerstein A, Goldenhersh MA, Vardy D, Nagler A. Local cutaneous reaction induced by subcutaneous interleukin-2 and interferon alpha-2a immunotherapy following ABMT. Bone Marrow Transplant 1993 11 : 443.
7. Detmar U, Agathos M, Nerl C. Allergy of delayed type of recombinant interferon alpha-2C. Contact Derm 1989 20 : 149.
8. Christian MM, Diven DG, Sanchez Rl, Soloway RD. Injection site vasculitis in a patient receiving interferon alfa for chronic hepatitis C. J Am Acad Dermatol 1997 37 : 118.
9. Sparsa A, Loustaud-Ratti V, Liozon E, et al. Cutaneous reactions or necrosis from interferon alpha: can interferon be reintroduced after healing? Six case reports. Rev Med Interne 2000 21 : 756.
10. Sasseville D, Ghamdi WA, Khenaizan SA. Interferon-induced cutaneous necrosis. J Cutan Med Surg 1999 3 : 320.
11. Sanders S, Busam K, Tahan SR, Jonhson RA, Sachs D. Granulomatous and suppurative dermatitis at interferon alfa injection sites: report of two cases. J Am Acad Dermatol 2002 46 : 611.
12. Elgart GW, Sheremata W, Ahn YS. Cutaneous reactions to recombinant human interferon beta-1b: the clinical and histologic spectrum. J Am Acad Dermatol 1997 37 : 553.
13. Benito-León J, Borbujo J, Cortés L. Cutaneous mucinoses complicating interferon beta-1b therapy. Eur Neurol 2002 47 : 123.
14. Arnason BGW, Reder AT. Interferons and multiple sclerosis. Clin Neuropharmacol 1994 17 : 495.
15. Cozzolino F, Torcia M, Lucibello M, et al. Interferon-alfa and interleukin 2 synergistically enhace basic fibroblast growth factor síntesis and induce release, promoting endotelial cell growth. J Clin Invest 1993 91 : 205.