Genomic imprinting of insulin-like growth factor 2 (IGF-2) in chronic synovitis

Growth Hormone and IGF Research

Volumn 17, Issue 6, 2007, Pages 500-505

  Moller B ^a   Kerschbaumer, G ^b   Komor, M ^b   Kerschbaumer, F ^b   Ottmann, O G ^b   Hoelzer, D ^b   Hofmann, W K ^c  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^c CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Imprinting; Insulin like growth factor 2; Rheumatoid arthritis

Indexed keywords

AZATHIOPRINE; CD19 ANTIGEN; DISEASE MODIFYING ANTIRHEUMATIC DRUG; ETANERCEPT; LEFLUNOMIDE; METHOTREXATE; MITOGENIC AGENT; PREDNISOLONE; SALAZOSULFAPYRIDINE; SOMATOMEDIN B;

ADOLESCENT; ADULT; AGED; ARTICLE; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL CULTURE; CHRONIC DISEASE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENOME IMPRINTING; GENOTYPE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; LYMPHOCYTE ACTIVATION; LYMPHOCYTE PROLIFERATION; MALE; MONONUCLEAR CELL; PERIPHERAL BLOOD MONONUCLEAR CELL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; REPEATED DRUG DOSE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SYNOVITIS; SYNOVIUM;

ADOLESCENT; ADULT; AGED; ARTHRITIS, RHEUMATOID; B-LYMPHOCYTES; CELLS, CULTURED; CHRONIC DISEASE; FEMALE; GENOMIC IMPRINTING; HETEROZYGOTE; HUMANS; INSULIN-LIKE GROWTH FACTOR II; LYMPHOCYTE ACTIVATION; MALE; MIDDLE AGED; MITOGENS; SYNOVIAL MEMBRANE; SYNOVITIS; T-LYMPHOCYTES;

EID: 36048985076     PISSN: 10966374     EISSN: 15322238     Source Type: Journal    
DOI: 10.1016/j.ghir.2007.05.003     Document Type: Article

References (30)

1. Giannoukakis N., Deal C., Paquette J., Goodyer C.G., and Polychronakos C. Parental genomic imprinting of the human IGF2 gene. Nat. Genet. 4 (1993) 98-101
2. Falls J.G., Pulford D.J., Wylie A.A., and Jirtle R.L. Genomic imprinting: implications for human disease. Am. J. Pathol. 154 (1999) 635-647
3. Huizinga T.W. Genetics in rheumatoid arthritis. Best Pract. Res. Clin. Rheumatol. 17 (2003) 703-716
4. Kubota T., Saitoh S., Matsumoto T., Narahara K., Fukushima Y., Jinno Y., et al. Excess functional copy of allele at chromosomal region 11p15 may cause Wiedemann-Beckwith (EMG) syndrome. Am. J. Med. Genet. 49 (1994) 378-383
5. Mutter G.L. Role of imprinting in abnormal human development. Mutat. Res. 396 (1997) 141-147
6. Morison I.M., Eccles M.R., and Reeve A.E. Imprinting of insulin-like growth factor 2 is modulated during hematopoiesis. Blood 96 (2000) 3023-3028
7. Hofmann W.K., Takeuchi S., Frantzen M.A., Hoelzer D., and Koeffler H.P. Loss of genomic imprinting of insulin-like growth factor 2 is strongly associated with cellular proliferation in normal hematopoietic cells. Exp. Hematol. 30 (2002) 318-323
8. Polychronakos C., Giannoukakis N., and Deal C.L. Imprinting of IGF2, insulin-dependent diabetes, immune function, and apoptosis: a hypothesis. Dev. Genet. 17 (1995) 253-262
9. Davies S.M. Developmental regulation of genomic imprinting of the IGF2 gene in human liver. Cancer Res. 54 (1994) 2560-2562
10. Nakagawa H., Chadwick R.B., Peltomaki P., Plass C., Nakamura Y., and de La Chapelle A. Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer. Proc. Natl. Acad. Sci. USA 98 (2001) 591-596
11. Zhan S., Shapiro D., Zhan S., Zhang L., Hirschfeld S., Elassal J., et al. Concordant loss of imprinting of the human insulin-like growth factor II gene promoters in cancer. J. Biol. Chem. 270 (1995) 27983-27986
12. Ogawa O., Eccles M.R., Szeto J., McNoe L.A., Yun K., Maw M.A., et al. Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour. Nature 362 (1993) 749-751
13. Cui H., Cruz-Correa M., Giardiello F.M., Hutcheon D.F., Kafonek D.R., Brandenburg S., et al. Loss of IGF2 imprinting: a potential marker of colorectal cancer risk. Science 299 (2003) 1753-1755
14. Hansenne I., Renard-Charlet C., Greimers R., and Geenen V. Dendritic cell differentiation and immune tolerance to insulin-related peptides in Igf2-deficient mice. J. Immunol. 176 (2006) 4651-4657
15. Kecha O., Brilot F., Martens H., Franchimont N., Renard C., Greimers R., et al. Involvement of insulin-like growth factors in early T cell development: a study using fetal thymic organ cultures. Endocrinology 141 (2000) 1209-1217
16. Derbinski J., Gabler J., Brors B., Tierling S., Jonnakuty S., Hergenhahn M., et al. Promiscuous gene expression in thymic epithelial cells is regulated at multiple levels. J. Exp. Med. 202 (2005) 33-45
17. Arnett F.C. Revised criteria for the classification of rheumatoid arthritis. Bull. Rheum. Dis. 38 (1989) 1-6
18. Baecklund E., Iliadou A., Askling J., Ekbom A., Backlin C., Granath F., et al. Association of chronic inflammation, not its treatment, with increased lymphoma risk in rheumatoid arthritis. Arthritis Rheum. 54 (2006) 692-701
19. Lynn A.H., Kwoh C.K., Venglish C.M., Aston C.E., and Chakravarti A. Genetic epidemiology of rheumatoid arthritis. Am. J. Hum. Genet. 57 (1995) 150-159
20. Page G., Lebecque S., and Miossec P. Anatomic localization of immature and mature dendritic cells in an ectopic lymphoid organ: correlation with selective chemokine expression in rheumatoid synovium. J. Immunol. 168 (2002) 5333-5341
21. Klimiuk P.A., Yang H., Goronzy J.J., and Weyand C.M. Production of cytokines and metalloproteinases in rheumatoid synovitis is T cell dependent. Clin. Immunol. 90 (1999) 65-78
22. Goronzy J.J., Henel G., Sawai H., Singh K., Lee E.B., Pryshchep S., et al. Costimulatory pathways in rheumatoid synovitis and T-cell senescence. Ann. NY Acad. Sci. 1062 (2005) 182-194
23. Salmon M., Scheel-Toellner D., Huissoon A.P., Pilling D., Shamsadeen N., Hyde H., et al. Inhibition of T cell apoptosis in the rheumatoid synovium. J. Clin. Invest. 99 (1997) 439-446
24. Davis L.S. A question of transformation: the synovial fibroblast in rheumatoid arthritis. Am. J. Pathol. 162 (2003) 1399-1402
25. Huang C.M., Tsai C.H., Tsai J.J., Kung P.T., Chen C.L., and Tsai F.J. The relationship between insulin-like growth factor-II gene Apa I polymorphism and rheumatoid arthritis. Scand. J. Rheumatol. 33 (2004) 126-127
26. Keyszer G.M., Heer A.H., Kriegsmann J., Geiler T., Keysser C., Gay R.E., et al. Detection of insulin-like growth factor I and II in synovial tissue specimens of patients with rheumatoid arthritis and osteoarthritis by in situ hybridization. J. Rheumatol. 22 (1995) 275-281
27. Lee S.D., Chen L.M., Kuo W.W., Shu W.T., Kuo W.H., Huang E.J., et al. Serum insulin-like growth factor-axis and matrix metalloproteinases in patients with rheumatic arthritis or rheumatic heart disease. Clin. Chim. Acta 367 (2006) 62-68
28. Lemmey A., Maddison P., Breslin A., Cassar P., Hasso N., McCann R., et al. Association between insulin-like growth factor status and physical activity levels in rheumatoid arthritis. J. Rheumatol. 28 (2001) 29-34
29. Kvien T.K. Epidemiology and burden of illness of rheumatoid arthritis. Pharmacoeconomics 22 (2004) 1-12
30. Neidhart M., Rethage J., Kuchen S., Kunzler P., Crowl R.M., Billingham M.E., et al. Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. Arthritis Rheum. 43 (2000) 2634-2647