Protective effects of Hibiscus tiliaceus L. methanolic extract to V79 cells against cytotoxicity and genotoxicity induced by hydrogen peroxide and tert-butyl-hydroperoxide

Toxicology in Vitro

Volumn 21, Issue 8, 2007, Pages 1442-1452

  Rosa, Renato Moreira ^a   Moura, Dinara Jaqueline ^a   Melecchi, Maria Inês S ^a   dos Santos, Rafael Santos ^a   Richter, Marc François ^b   Camarão, Elina Bastos ^a   Henriques, João Antonio Pêgas ^a,b   de Paula Ramos, Ana Lígia Lia ^a   Saffi, Jenifer ^a,b  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

^b UNIVERSIDADE LUTERANA DO BRASIL   (Brazil)

Author keywords

Antioxidant; DNA damage; Genotoxicity; Hibiscus tiliaceus L.; Micronuclei frequency; Oxidative stress; Phytotherapic

Indexed keywords

DNA; GLUTATHIONE; HIBISCUS TILIACEUS EXTRACT; HYDROGEN PEROXIDE; HYDROXYL RADICAL; METHANOL EXTRACTION RESIDUE; PLANT EXTRACT; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; CHINESE HAMSTER; CLONAL SURVIVAL ASSAY; CLONE; COMET ASSAY; CYTOTOXICITY; DNA DAMAGE; GENOTOXICITY; GLUTATHIONE METABOLISM; HIBISCUS; HIBISCUS TILIACEUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INHIBITION KINETICS; LIPID PEROXIDATION; MICRONUCLEUS TEST; MOLECULAR MODEL; NONHUMAN; OXIDATIVE STRESS; PHOTOCHEMICAL QUENCHING;

ANIMALS; CELL LINE; CHROMOSOMES; CRICETINAE; CYTOTOXINS; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FREE RADICAL SCAVENGERS; GLUTATHIONE; HIBISCUS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LIPID PEROXIDATION; MUTAGENS; PLANT EXTRACTS; TERT-BUTYLHYDROPEROXIDE;

HIBISCUS; HIBISCUS TILIACEUS;

EID: 36048970121     PISSN: 08872333     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tiv.2007.06.004     Document Type: Article

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