Class I MHC allochimeric presentation of composite immunogenic and self epitopes induces tolerance to genetically diverse rat strains

Cellular Immunology

Volumn 248, Issue 1, 2007, Pages 48-58

  Semiletova, Natalya V ^a   Shen, Xiu Da ^a   Feldman, Daniel M ^a   Gao, Feng ^a   Mhoyan, Ana ^a   Liu, Dhai ^a   Busuttil, Ronald W ^a   Kupiec Weglinski, Jerzy W ^a   Ghobrial, Rafik M ^a  

^a UCLA MEDICAL CENTER   (United States)

Author keywords

Allo antibody; Allochimeric protein; Cardiac allograft; Humoral immunity; MHC class I; Tolerance

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1;

ALLOGRAFT; ALPHA HELIX; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL INFILTRATION; CHIMERA; COMPOSITE GRAFT; CONTROLLED STUDY; CYTOKINE PRODUCTION; EPITOPE MAPPING; GENETIC VARIABILITY; HEART GRAFT; HUMORAL IMMUNITY; IMMUNOGENICITY; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGICAL TOLERANCE; MAJOR HISTOCOMPATIBILITY COMPLEX; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; STRAIN DIFFERENCE;

ANIMALS; GRAFT REJECTION; GRAFT SURVIVAL; HEART TRANSPLANTATION; HISTOCOMPATIBILITY ANTIGENS CLASS I; IMMUNE TOLERANCE; IMMUNODOMINANT EPITOPES; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; IMMUNOHISTOCHEMISTRY; INJECTIONS, INTRAVENOUS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-2; INTERLEUKIN-4; ISOANTIGENS; MAJOR HISTOCOMPATIBILITY COMPLEX; MUTANT CHIMERIC PROTEINS; RATS; RATS, INBRED ACI; RATS, INBRED BN; RATS, INBRED LEW; RATS, INBRED WF; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; SPECIES SPECIFICITY; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, HOMOLOGOUS; VARIATION (GENETICS);

RATTUS;

EID: 36048969294     PISSN: 00088749     EISSN: 10902163     Source Type: Journal    
DOI: 10.1016/j.cellimm.2007.04.008     Document Type: Article

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