Resolution of asymptomatic myocardial ischemia in patients with type 2 diabetes in the Detection of Ischemia in Asymptomatic Diabetics (DIAD) study

Diabetes Care

Volumn 30, Issue 11, 2007, Pages 2892-2898

  Wackers, Frans J Th ^a   Chyun, Deborah A ^b   Young, Lawrence H ^a   Heller, Gary V ^c   Iskandrian, Ami E ^d   Davey, Janice A ^a   Barrett, Eugene J ^e   Taillefer, Raymond ^f   Wittlin, Steven D ^g   Filipchuk, Neil ^h   Ratner, Robert E ⁱ   Inzucchi, Silvio E ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b YALE UNIVERSITY SCHOOL OF NURSING   (United States)

^c HARTFORD HOSPITAL   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e UNIVERSITY OF VIRGINIA   (United States)

^f UNIVERSITÉ DE MONTRÉAL   (Canada)

^g UNIVERSITY OF ROCHESTER   (United States)

^h Cardiology Consultants   (Canada)

ⁱ MEDSTAR RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; METHOXY ISOBUTYL ISONITRILE TECHNETIUM TC 99M;

ADULT; AGED; ARTICLE; CARDIOVASCULAR RISK; DIABETIC PATIENT; FEMALE; HEART INFARCTION; HEART MUSCLE ISCHEMIA; HEART PERFUSION; HUMAN; IMAGING; MAJOR CLINICAL STUDY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; REVASCULARIZATION; RISK FACTOR; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; TREATMENT OUTCOME;

ADENOSINE; AGED; CONTINENTAL POPULATION GROUPS; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEMALE; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PREVALENCE; RADIOPHARMACEUTICALS; REPRODUCIBILITY OF RESULTS; TECHNETIUM TC 99M SESTAMIBI; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 36048965509     PISSN: 01495992     EISSN: 01495992     Source Type: Journal    
DOI: 10.2337/dc07-1250     Document Type: Article

References (25)

1. Wackers FJTh, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, Taillerfer R, Wittlin SD, Heller GV, Filipchuk N, Engel S, Ratner RE, Iskandrian AE, Detection of Ischemia in Asymptomatic Diabetics (DIAD) Investigators: Detection of silent myocardial ischemia in asymptomatic patients with type 2 diabetes (the DIAD study). Diabetes Care 27:1954-1961, 2004
2. Huxley R, Barzi F, Woodward M: Excess risk of fatal coronary heart disease associated with diabetes in men and women: meta-analysis of 37 prospective cohort studies. BMJ 332:73-78, 2006
3. DePuey GE: Imaging guidelines for nuclear cardiology procedures. J Nucl Cardiol 13:e21-e171, 2006
4. Liu YH, Sinusas AJ, DeMan P, Zaret BL, Wackers FJTh: Quantification of single photon emission computerized tomographic myocardial perfusion images: methodology and validation of the Yale-CQ method. J Nucl Cardiol 6:190-203, 1999
5. Liu YH, Sinusas AJ, Khaimov D, Gebuza BI, Wackers FJTh: New hybrid count and geometry-based method for quantification of left ventricular volumes and ejection fraction from ECG-gated SPECT: methodology and validation. J Nucl Cardiol 12:55-65, 2005
6. Abbot BG, Afshar M, Berger AK, Wackers FJTh: Prognostic significance of ischemic electrocardiographic changes during adenosine infusion in patients with normal myocardial perfusion imaging. J Nucl Cardiol 10:9-16, 2003
7. 99mTc: a phantom study. J Nucl Med 41:1436-1441, 2004
8. SAS. Version 9.1. Cary, NC, SAS Institute, 2002-2003
9. Bland JM, Altman DG: Statistical methods for assessing agreement between two methods of clinical measurement. Lancet 1:307-310, 1986
10. American Diabetes Association: Clinical practice recommendations 2001. Position statement: management of dyslipidemia in adults with diabetes. Diabetes Care 24:S58-S61, 2001
11. Schwartz RG, Pearson TA, Kalaria VG, Mackin ML, Williford DJ, Awasthi A, Shah A, Rains A, Guido JJ: Prospective evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy. J Am Coll Cardiol 42:600-610, 2003
12. Sdringola S, Nakagawa K, Nakagawa Y, Yusuf SW, Boccalandro F, Mullani N, Haynie M, Hess MJ, Gould KL: Combined intense lifestyle and pharmacologic lipid treatment further reduce coronary events and myocardial perfusion abnormalities compared with usual-care cholesterol-lowering drugs in coronary artery disease. J Am Coll Cardiol 41:263-272, 2003
13. Libby P, Sasiela W: Plaque stabilization: can we turn theory into evidence? Am J Cardiol 98:26P-33P, 2006
14. Nissen SE, Nicholls SJ, Sipahi I, Libby P, Raichlen JS, Ballantyne CM, Davignon J, Erbel R, Fruchart JC, Tardif JC, Schoenhagen P, Crowe T, Cain V, Wolski K, Goormastic M, Tuzcu EM, ASTEROID Investigators: Effect of very high-intensity statin therapy on regression of coronary atherosclerosis: the ASTEROID trial. JAMA 295:1556-1565, 2006
15. Ambrose JA, Martinez EE: A new paradigm for plaque stabilization. Circulation 105:2000-2004, 2002
16. Klein LW: Atherosclerosis regression, vascular remodeling, and plaque stabilization. J Am Coll Cardiol 49:271-273, 2007
17. Corti R, Farkouh ME, Badimon JJ: The vulnerable plaque and acute coronary syndrome. Am J Med 113:668-680, 2002
18. Rajagopalan N, Miller TD, Hodge DO, Frye RL, Gibbons RJ: Identifying highrisk asymptomatic diabetic patients who are candidates for screening stress singlephoton emission computed tomography imaging. J Am Coll Cardiol 45:43-49, 2005
19. Klodas E, Miller TD, Christian TF, Hodge DO, Gibbons RJ: Prognostic significance of ischemic electrocardiographic changes during vasodilator stress testing in patients with normal SPECT images. J Nucl Cardiol 10:4-8, 2003
20. Alazraki NP, Krawczynska, DePuey EG, Ziffer JA, Vansant JP, Pettigrew RI, Taylor A, King SB, Garcia EV: Reproducibility of thallium-201 SPECT studies. J Nucl Med 35:1237-1244, 1994
21. Mahmarian JJ, Moyé LA, Verani MS, Bloom MF, Pratt CM: High reproducibility of myocardial perfusion defects in patients undergoing serial exercise thallium-201 tomography. Am J Cardiol 75:1116-1119, 1995
22. Wackers FJTh, Bodenheimer M, Fleiss JL, Brown M, MSSMI Tl-201 Investigators: Factors affecting uniformity in interpretation of planar Tl-201 imaging in a multicenter trial. J Am Coll Cardiol 21:1064-1074, 1993
23. Boden WE, O'Rourke RA, Teo KK, Hartigan PM, Maron DJ, Kostuk WJ, Knudtson M, Dada M, Casperson P, Harris CL, Chaitman BR, Shaw L, Gosselin G, Nawaz S, Title LM, Gau G, Blaustein AS, Booth DC, Bates ER, Spertus JA, Berman DS, Mancini GB, Weintraub WS, COURAGE Trial Research Group: Optimal medical therapy with or without PCI for stable coronary artery disease. N Engl J Med 356:1503-1516, 2007
24. Mahmarian JJ, Dakik HA, Filipchuk NG, Shaw LJ, Iskander SS, Ruddy TD, Keng F, Henzlova MJ, Allam A, Moyé LA, Pratt CM, INSPIRE Investigators: An initial strategy of intense medical therapy is comparable to that of coronary revascularization for suppression of scintigraphic ischemia in high-risk but stable survivors of acute myocardial infarction. J Am Coll Cardiol 48:2458-2467, 2006
25. Sobel BE, Frye R, Detre KM: Burgeoning dilemmas in the management of diabetes and cardiovascular disease: rationale for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) trial. Circulation 107:636-642, 2003