메뉴 건너뛰기




Volumn 8, Issue 5, 2007, Pages 337-344

Stavudine but not didanosine as part of HAART contributes to peripheral lipoatrophy: A substudy from the Antiretroviral Regimen Evaluation Study (ARES)

Author keywords

DEXA scan; Didanosine; HAART; HIV; Lipoatrophy; Stavudine

Indexed keywords

DIDANOSINE; LAMIVUDINE; NELFINAVIR; NEVIRAPINE; RITONAVIR; SAQUINAVIR; STAVUDINE;

EID: 36048956410     PISSN: 15284336     EISSN: None     Source Type: Journal    
DOI: 10.1310/hct0805-337     Document Type: Article
Times cited : (14)

References (30)
  • 1
    • 11344293751 scopus 로고    scopus 로고
    • Cardiovascular risk and body-fat abnormalities in HIV-infected adults
    • Grinspoon S, Carr A. Cardiovascular risk and body-fat abnormalities in HIV-infected adults. N Engl J Med. 2005;352:48-62.
    • (2005) N Engl J Med , vol.352 , pp. 48-62
    • Grinspoon, S.1    Carr, A.2
  • 2
    • 0242449221 scopus 로고    scopus 로고
    • HIV-associated adipose redistribution syndrome as a selective autonomic neuropathy
    • Fliers E, Sauerwein HP, Romijn JA, et al. HIV-associated adipose redistribution syndrome as a selective autonomic neuropathy. Lancet. 2003;362:1758-1760.
    • (2003) Lancet , vol.362 , pp. 1758-1760
    • Fliers, E.1    Sauerwein, H.P.2    Romijn, J.A.3
  • 4
    • 0033924871 scopus 로고    scopus 로고
    • Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection
    • Mallal SA, John M, Moore CB, James IR, McKinnon EJ. Contribution of nucleoside analogue reverse transcriptase inhibitors to subcutaneous fat wasting in patients with HIV infection. AIDS. 2000;14:1309-1316.
    • (2000) AIDS , vol.14 , pp. 1309-1316
    • Mallal, S.A.1    John, M.2    Moore, C.B.3    James, I.R.4    McKinnon, E.J.5
  • 5
    • 0035805176 scopus 로고    scopus 로고
    • Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection
    • van der Valk M, Gisolf EH, Reiss P, et al. Increased risk of lipodystrophy when nucleoside analogue reverse transcriptase inhibitors are included with protease inhibitors in the treatment of HIV-1 infection. AIDS. 2001;15:847-855.
    • (2001) AIDS , vol.15 , pp. 847-855
    • van der Valk, M.1    Gisolf, E.H.2    Reiss, P.3
  • 6
    • 0346333250 scopus 로고    scopus 로고
    • Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level
    • Nolan D, Hammond E, James I, McKinnon E, Mallal S. Contribution of nucleoside-analogue reverse transcriptase inhibitor therapy to lipoatrophy from the population to the cellular level. Antiviral Ther. 2003;8:617-626.
    • (2003) Antiviral Ther , vol.8 , pp. 617-626
    • Nolan, D.1    Hammond, E.2    James, I.3    McKinnon, E.4    Mallal, S.5
  • 7
    • 22344455174 scopus 로고    scopus 로고
    • Redefining lipodystrophy syndrome. Risks and impact on clinical decision making
    • Lichtenstein KA. Redefining lipodystrophy syndrome. Risks and impact on clinical decision making. J Acquir Immune Defic Syndr. 2005;39:395-400.
    • (2005) J Acquir Immune Defic Syndr , vol.39 , pp. 395-400
    • Lichtenstein, K.A.1
  • 8
    • 30144440513 scopus 로고    scopus 로고
    • HIV-associated lipoatrophy: What are the kinder, gentler agents?
    • Dube MP. HIV-associated lipoatrophy: what are the kinder, gentler agents? Clin Infect Dis. 2006;42:281-282.
    • (2006) Clin Infect Dis , vol.42 , pp. 281-282
    • Dube, M.P.1
  • 9
    • 0037032941 scopus 로고    scopus 로고
    • Increased risk of lipoatrophy under stavudine in HIV-1 -infected patients: Results of a substudy from a comparative trial
    • Joly V, Flandre P, Meiffredy V, et al. Increased risk of lipoatrophy under stavudine in HIV-1 -infected patients: results of a substudy from a comparative trial. AIDS. 2002;16:2447-2454.
    • (2002) AIDS , vol.16 , pp. 2447-2454
    • Joly, V.1    Flandre, P.2    Meiffredy, V.3
  • 10
    • 3042734983 scopus 로고    scopus 로고
    • Prevalence of lipoatrophy and mitochondrial DNA content of blood and subcutaneous fat in HIV-1 -infected patients randomly allocated to zidovudine-or stavudine-based therapy
    • van der Valk M, Casula M, Weverling GJ, et al. Prevalence of lipoatrophy and mitochondrial DNA content of blood and subcutaneous fat in HIV-1 -infected patients randomly allocated to zidovudine-or stavudine-based therapy. Antiviral Ther. 2004;9:385-393.
    • (2004) Antiviral Ther , vol.9 , pp. 385-393
    • van der Valk, M.1    Casula, M.2    Weverling, G.J.3
  • 11
    • 26844543445 scopus 로고    scopus 로고
    • Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides
    • Dube MP, Parker RA, Tebas P, et al. Glucose metabolism, lipid, and body fat changes in antiretroviral-naive subjects randomized to nelfinavir or efavirenz plus dual nucleosides. AIDS. 2005;19:1807-1818.
    • (2005) AIDS , vol.19 , pp. 1807-1818
    • Dube, M.P.1    Parker, R.A.2    Tebas, P.3
  • 12
    • 33646811534 scopus 로고    scopus 로고
    • Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial
    • Mulligan K, Parker RA, Komarow L, et al. Mixed patterns of changes in central and peripheral fat following initiation of antiretroviral therapy in a randomized trial. J Acquir Immune Defic Syndr. 2006;41:590-597.
    • (2006) J Acquir Immune Defic Syndr , vol.41 , pp. 590-597
    • Mulligan, K.1    Parker, R.A.2    Komarow, L.3
  • 13
    • 0038708272 scopus 로고    scopus 로고
    • Prospective evaluation of the effects of antiretoviral therapy on body composition in HIV-1 infected men starting therapy
    • Mallon PWG, Miller J, Cooper DA, Carr A. Prospective evaluation of the effects of antiretoviral therapy on body composition in HIV-1 infected men starting therapy. AIDS. 2003;17:971-979.
    • (2003) AIDS , vol.17 , pp. 971-979
    • Mallon, P.W.G.1    Miller, J.2    Cooper, D.A.3    Carr, A.4
  • 14
    • 3042848853 scopus 로고    scopus 로고
    • Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: A 3-year randomized trial
    • Gallant JE, Staszewski S, Pozniak AL, et al. Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial. JAMA. 2004;292:191-201.
    • (2004) JAMA , vol.292 , pp. 191-201
    • Gallant, J.E.1    Staszewski, S.2    Pozniak, A.L.3
  • 15
    • 0037055028 scopus 로고    scopus 로고
    • Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: A randomized trial
    • Carr A, Workman C, Smith DE, et al. Abacavir substitution for nucleoside analogs in patients with HIV lipoatrophy: a randomized trial. JAMA. 2002;288:207-215.
    • (2002) JAMA , vol.288 , pp. 207-215
    • Carr, A.1    Workman, C.2    Smith, D.E.3
  • 16
    • 0038034454 scopus 로고    scopus 로고
    • Randomized, controlled, 48 week study of switching stavudine and/or protease inhibitors to Combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients
    • John M, McKinnon EJ, James IR, et al. Randomized, controlled, 48 week study of switching stavudine and/or protease inhibitors to Combivir/abacavir to prevent or reverse lipoatrophy in HIV-infected patients. J Acquir Immune Defic Syndr. 2003;33:29-33.
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 29-33
    • John, M.1    McKinnon, E.J.2    James, I.R.3
  • 17
    • 1642456562 scopus 로고    scopus 로고
    • Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: The results of the TARHEEL study
    • McComsey GA, Ward DJ, Hessenthaler SM, et al. Improvement in lipoatrophy associated with highly active antiretroviral therapy in human immunodeficiency virus-infected patients switched from stavudine to abacavir or zidovudine: the results of the TARHEEL study. Clin Infect Dis. 2004;38:263-270.
    • (2004) Clin Infect Dis , vol.38 , pp. 263-270
    • McComsey, G.A.1    Ward, D.J.2    Hessenthaler, S.M.3
  • 18
    • 0038644532 scopus 로고    scopus 로고
    • A 48-week, randomized, open-label comparison of three abacavir-based substitution approaches in the management of dyslipidemia and peripheral lipoatrophy
    • Moyle GJ, Baldwin C, Langroudi B, Mandalia S, Gazzard BG. A 48-week, randomized, open-label comparison of three abacavir-based substitution approaches in the management of dyslipidemia and peripheral lipoatrophy. J Acquir Immune Defic Syndr. 2003;33:22-28.
    • (2003) J Acquir Immune Defic Syndr , vol.33 , pp. 22-28
    • Moyle, G.J.1    Baldwin, C.2    Langroudi, B.3    Mandalia, S.4    Gazzard, B.G.5
  • 19
    • 33750227103 scopus 로고    scopus 로고
    • A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy
    • Moyle GJ, Sabin CA, Cartledge J, et al. A randomized comparative trial of tenofovir DF or abacavir as replacement for a thymidine analogue in persons with lipoatrophy. AIDS. 2006;20:2043-2050.
    • (2006) AIDS , vol.20 , pp. 2043-2050
    • Moyle, G.J.1    Sabin, C.A.2    Cartledge, J.3
  • 20
    • 0036499058 scopus 로고    scopus 로고
    • Role of long-term nucleoside-analogue therapy in lipodystrophy and metabolic disorders in human immunodeficency virus-infected patients
    • Chene G, Angelini E, Cotte L, et al. Role of long-term nucleoside-analogue therapy in lipodystrophy and metabolic disorders in human immunodeficency virus-infected patients. Clin Infect Dis. 2002;34:649-657.
    • (2002) Clin Infect Dis , vol.34 , pp. 649-657
    • Chene, G.1    Angelini, E.2    Cotte, L.3
  • 21
    • 19944431796 scopus 로고    scopus 로고
    • Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine
    • Shlay JC, Visnegarwala F, Bartsch G, et al. Body composition and metabolic changes in antiretroviral-naive patients randomized to didanosine and stavudine vs. abacavir and lamivudine. J Acquir Immune Defic Syndr. 2005;38:147-155.
    • (2005) J Acquir Immune Defic Syndr , vol.38 , pp. 147-155
    • Shlay, J.C.1    Visnegarwala, F.2    Bartsch, G.3
  • 22
    • 0012570692 scopus 로고    scopus 로고
    • Fat distribution evaluated by computed tomography and metabolic abnormalities in patients undergoing antiretroviral therapy: Preliminary results of the LIPOCO study
    • Saint-Marc T, Partisani M, Poizot-Martin I, et al. Fat distribution evaluated by computed tomography and metabolic abnormalities in patients undergoing antiretroviral therapy: preliminary results of the LIPOCO study. AIDS. 2000;14:37-49.
    • (2000) AIDS , vol.14 , pp. 37-49
    • Saint-Marc, T.1    Partisani, M.2    Poizot-Martin, I.3
  • 23
    • 3142697068 scopus 로고    scopus 로고
    • Efficacy and safety of emtricitabine vs stavudine in combination therapy in antiretroviral-naive patients: A randomized trial
    • Saag MS, Cahn P, Raffi F, et al. Efficacy and safety of emtricitabine vs stavudine in combination therapy in antiretroviral-naive patients: a randomized trial. JAMA. 2004;292:180-189.
    • (2004) JAMA , vol.292 , pp. 180-189
    • Saag, M.S.1    Cahn, P.2    Raffi, F.3
  • 24
    • 29744455075 scopus 로고    scopus 로고
    • Comparison of two once-daily regimens with a regimen consisting of nelfinavir, didanosine, and stavudine in antiretroviral therapy-naïve adults: 48-week results from the Antiretroviral Regimen Evaluation Study (ARES)
    • Lowe SH, Wensing AMJ, Hassink EAM, et al. Comparison of two once-daily regimens with a regimen consisting of nelfinavir, didanosine, and stavudine in antiretroviral therapy-naïve adults: 48-week results from the Antiretroviral Regimen Evaluation Study (ARES). HIV Clin Trials. 2005;6:235-245.
    • (2005) HIV Clin Trials , vol.6 , pp. 235-245
    • Lowe, S.H.1    Wensing, A.M.J.2    Hassink, E.A.M.3
  • 25
    • 33747122666 scopus 로고    scopus 로고
    • Treatment for adult HIV infection: 2006 Recommendations of the International AIDS Society-USA Panel
    • Hammer SM, Saag MS, Schechter M, et al. Treatment for adult HIV infection: 2006 Recommendations of the International AIDS Society-USA Panel. JAMA. 2006;296:827-843.
    • (2006) JAMA , vol.296 , pp. 827-843
    • Hammer, S.M.1    Saag, M.S.2    Schechter, M.3
  • 26
    • 33750454570 scopus 로고    scopus 로고
    • Department of Health and Human Services (DHHS) Panel on Antiretroviral Guidelines for Adults and Adolescents, A working group of the Office of AIDS Research Advisory Council OARAC, October 10, Available at
    • Department of Health and Human Services (DHHS) Panel on Antiretroviral Guidelines for Adults and Adolescents - A working group of the Office of AIDS Research Advisory Council (OARAC). Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents (October 10, 2006). Available at: http://AIDSinfo.nih.gov.
    • (2006) Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents
  • 27
    • 30944468562 scopus 로고    scopus 로고
    • Tenofovir Df, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV
    • Gallant J, DeJesus E, Arribas JR, et al. Tenofovir Df, emtricitabine, and efavirenz vs. zidovudine, lamivudine, and efavirenz for HIV. N Engl J Med. 2006;354:251-260.
    • (2006) N Engl J Med , vol.354 , pp. 251-260
    • Gallant, J.1    DeJesus, E.2    Arribas, J.R.3
  • 28
    • 36049048723 scopus 로고    scopus 로고
    • Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study
    • Epub ahead of print
    • Podzamczer D, Ferrer E, Sanchez P, et al. Less lipoatrophy and better lipid profile with abacavir as compared to stavudine: 96-week results of a randomized study. J Acquir Immune Defic Syndr. 2006 [Epub ahead of print].
    • (2006) J Acquir Immune Defic Syndr
    • Podzamczer, D.1    Ferrer, E.2    Sanchez, P.3
  • 29
    • 30144443508 scopus 로고    scopus 로고
    • Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients
    • Jemsek JG, Arathoon E, Arlotti M, et al. Body fat and other metabolic effects of atazanavir and efavirenz, each administered in combination with zidovudine plus lamivudine, in antiretroviral-naive HIV-infected patients. Clin Infect Dis. 2006;42:273-280.
    • (2006) Clin Infect Dis , vol.42 , pp. 273-280
    • Jemsek, J.G.1    Arathoon, E.2    Arlotti, M.3
  • 30
    • 0035715574 scopus 로고    scopus 로고
    • Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz
    • Maggiolo F, Migliorino M, Maserati R, et al. Virological and immunological responses to a once-a-day antiretroviral regimen with didanosine, lamivudine and efavirenz. Antiviral Ther. 2001;6:249-253.
    • (2001) Antiviral Ther , vol.6 , pp. 249-253
    • Maggiolo, F.1    Migliorino, M.2    Maserati, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.