Exposure of hematopoietic stem cells to ethylene oxide during processing represents a potential carcinogenic risk for transplant recipients

Regulatory Toxicology and Pharmacology

Volumn 49, Issue 3, 2007, Pages 149-153

  Butterworth, Byron E ^a   Chapman, John R ^b  

^a Butterworth Consulting   (United States)

^b Thermogenesis Corp   (United States)

Author keywords

Bone marrow transplantation; Cord blood; Donor cell derived leukemia; Ethylene oxide; Hematopoietic stem cell transplantation; Leukemia risk

Indexed keywords

CHEMOSTERILANT; ETHYLENE OXIDE;

ANIMAL CELL; ARTICLE; BONE MARROW TRANSPLANTATION; CANCER RISK; CONTROLLED STUDY; DISPOSABLE EQUIPMENT; DONOR CELL DERIVED LEUKEMIA; ELECTRON BEAM; FOOD AND DRUG ADMINISTRATION; FREEZING; GAMMA RADIATION; GENE MUTATION; GENOTOXICITY; HEMATOPOIETIC STEM CELL; HUMAN; HUMAN CELL; INSTRUMENT STERILIZATION; LEUKEMIA; MOUSE; NONHUMAN; PERIPHERAL CIRCULATION; PRECANCER; PRIORITY JOURNAL; RAT; SAFETY; STEM CELL TRANSPLANTATION; STORAGE; TUBE; UMBILICAL CORD BLOOD; UNITED STATES;

MUS; RATTUS;

EID: 36048948263     PISSN: 02732300     EISSN: 10960295     Source Type: Journal    
DOI: 10.1016/j.yrtph.2007.07.004     Document Type: Note

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