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General procedure for the synthesis of imidazole: A mixture of an aldehyde (0.5 mmol, benzoin (0.5 mmol, NH4OAc (1.5 mmol, and DIB (0.5 mmol) in ethanol (5 mL) was refluxed for 30-60 min. The reaction was monitored by TLC. After completion, the mixture was cooled and the solvent was removed under reduced pressure. Saturated aq, NaHCO3 (10 mL) was added and the mixture was extracted with EtOAc (3 × 10 mL, The extract was dried and concentrated. The residue was subjected to column chromatography (silica gel, hexane-EtOAc) to obtain pure imidazole derivative. The spectral (1H NMR and MS) data of some representative imidazoles are given below. Compound 2: 1H NMR (200 MHz, CDCl3, δ 12.16 (1H, brs, 8.06 (2H, d, J, 8.0Hz, 7.60-7.42 (4H, m, 7.40-7.06 (8H, m, FAB-MS: m/z 355, 353 [M, Na, Compound 4: 1H NMR (200 MHz, CDCl3, δ 12.68 (1H, brs, 8.39-8.21 4H, m, 7
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