Aminolevulinic acid photodynamic therapy for cosmetic uses on the skin

Giornale Italiano di Dermatologia e Venereologia

Volumn 142, Issue 4, 2007, Pages 311-326

  Gold, M H ^a,b  

^a GOLD SKIN CARE CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Aminolevulinic acid; Lasers; Photodynamic therapy; Photosensitizing agents

Indexed keywords

AKTILITE; AMINOLEVULINIC ACID; AMINOLEVULINIC ACID METHYL ESTER; BLUU; KERASTICK; PHOTOSENSITIZING AGENT; PROTOPORPHYRIN; UNCLASSIFIED DRUG;

ACNE VULGARIS; ACTINIC KERATOSIS; ALOPECIA AREATA; BASAL CELL CARCINOMA; BOWEN DISEASE; BOWENOID PAPULOSIS; CLINICAL FEATURE; CLINICAL TRIAL; CRYOTHERAPY; CUTANEOUS T CELL LYMPHOMA; DISEASE COURSE; DISEASE SEVERITY; DRUG APPROVAL; DRUG EFFECT; ESTHETIC SURGERY; HEALTH CARE SYSTEM; HEALTH PROGRAM; HUMAN; KAPOSI SARCOMA; LASER; MEDICAL SOCIETY; MELANOMA; MOLLUSCUM CONTAGIOSUM; OUTCOME ASSESSMENT; PHOTODYNAMIC THERAPY; PSORIASIS VULGARIS; REVIEW; SKIN DISEASE; SQUAMOUS CELL CARCINOMA; SYMPTOM; TREATMENT DURATION; TREATMENT INDICATION; UNITED STATES;

EID: 36048934068     PISSN: 03920488     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (64)

1. Raab O. Ueber die Wirkung fluoreszierenden Stoffe auf infusorien. Z Biol 1900;39:524-6.
2. Von Tappeiner H, Jodblauer A. Uber die Wirkung der photodynamischen (fluorescierenden) staffe auf protozoan und enzyme. Dtsch Arch Klin Med 1904;80:427-87.
3. Jesionek A, Von Tappeiner H. Behandlung der hautcarcinome nut fluorescierenden Stoffen. Dtsch Arch Klin Med 1905;85:223-7.
4. Hausman W. Die sensibilisierende Wirkung des hamatoporphyrins. Biochem Zeit 1911:276-316.
5. Meyer-Betz F. Untersuchungen uber die bioloische (photodynamische) Wirkung des hamatoporphyrins und anderer derivative des blutund gallenfarbstoffs. Dtsch Arch Klin Med 1913;112:476-503.
6. Auler H, Banzer G. Untersuchungen ueber die rolle der porphyrine bei geschwulstkranken menschen und tieren. Z Krebsforsch 1942;53:65-8.
7. Figge FHJ, Weiland GS, Manganiello LDJ. Cancer detection and therapy. Affinity of neoplastic embryonic and traumatized tissue for porphyrins and metalloporphyrins. Proc Soc Exp Biol Med 1948;68:640.
8. Dougherty TJ, Kaufman JE, Goldfarb A, Weishaupt KR, Boyle D, Mittleman A. Photoradiation therapy for the treatment of malignant tumors. Cancer Res 1978;38:2628-35.
9. Kennedy JC, Pottier RH, Pross DC. Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experiences. J Photochem Photobiol B 1990;6:143-8.
10. Gold MH, Goldman MP. 5-Aminolevulinic acid photodynamic therapy: where we have been and where we are going. Dermatol Surg 2004;30:1077-84.
11. Jeffes EW, McCullough JL, Weinstein GD, Kaplan R, Glazer SD, Taylor JR. Photodynamic therapy of actinic keratoses with topical aminolevulinic acid hydrochloride and fluorescent blue light. J Am Acad Dermatol 2001;45:96-104.
12. Jeffes EW. Levulan: the first approved topical photosensitizer for the treatment of actinic keratosis. J Dermatolog Treat 2002;13 Suppl 1:S19-23.
13. Nestor MS, Goldberg DJ, Goldman MP, Weiss RA, Rigel DS. Photorejuvenation: non-ablative skin rejuvenation using intense pulsed light. Skin Aging 2003;3:8.
14. Goldman M, Eckhouse S. Photothermal sclerosis of leg veins. Dermatol Surg 1996;22:323-30.
15. Anderson RR, Parish JA. Selective photothermolysis: precise microsurgery by selective absorption of pulsed radiation. Science 1983;220:524-7.
16. Biter PH. Noninvasive rejuvenation of photodamaged skin using serial, full-face intense pulsed light treatments. Dermatol Surg 2000;26:835-42.
17. Goldberg DJ, Cutler KB. Non-ablative treatment of rhytids with intense pulsed light. Lasers Surg Med 2000;26:196-200.
18. Weiss RA, Weiss MA, Beasley KL. Rejuvenation of photoaged skin: 5 years results with intense pulsed light of the face, neck and chest. Der-matol Surg 2002;28:115-9.
19. Negishi K, Tezuka Y, Kushikata N, Wakamatsu S. Photorejuvenation for Asian skin by intense pulsed light. Dermatol Surg 2001;27:627-31; discussion 632.
20. Hernandez-Perez E. Gross and microscopic findings in patients submitted to nonablative full-face resurfacing using intense pulsed light: a preliminary study. Dermatol Surg 2002;28:651-5.
21. Nestor MS, Gold MH, Kauvar AN. The use of photodynamic therapy in dermatology: results of a consensus conference. J Drugs Dermatol 2006;5:140-54.
22. Alexiades-Armenakas MR, Geronemus RG. Laser-mediated photodynamic therapy of actinic keratoses. Arch Dermatol 2003t;139:1313-20.
23. Gold MH. The evolving role of aminolevulinic acid hydrochloride with photodynamic therapy in photoaging. Cutis 2002;69(6 Suppl):8-13.
24. Touma D, Yaar M, Whitehead S, Konnikov N, Gilchrest BA. A trial of short incubation, broad-area photodynamic therapy for facial actinic keratoses and diffuse photodamage. Arch Dermatol 2004;140:33-40.
25. Ruiz-Rodriguez R, Sanz-Sanchez T, Cordoba S. Photodynamic photorejuvenation. Dermatol Surg 2002;28:742-4.
26. Gold MH, Bradshaw VL, Boring MM, Bridges TM, Biron JA, Lewis TL. Treatment of sebaceous gland hyperplasia by photodynamic therapy with 5-aminolevulinic acid and a blue light source or intense pulsed light source. J Drugs Dermatol 2004;3(6 Suppl):S6-9.
27. Goldman MP, Atkin D, Kincad S. PDT/ALA in the treatment of actinic damage: real world experience. J Lasers Surg Med 2002;14 Suppl:24.
28. Avram DK, Goldman MP. Effectiveness and safety of ALA-IPL in treating actinic keratoses and photodamage. J Drugs Dermatol 2004;3(1 Suppl):S36-9.
29. Alexiades-Armenakas MR, Geronemus RG. Laser-mediated photodynamic therapy of actinic chelitis. J Drugs Dermatol 2004;3:548-51.
30. Alster TS, Tanzi EL, Welch EC. Photorejuvenation of facial skin with topical 20% 5-aminolevulinic acid and intense pulsed light treatment: a split-face comparison study. J Drugs Dermatol 2005;4:35-8.
31. Key DJ. Aminolevulinic acid-pulsed dye laser photodynamic therapy for the treatment of photoaging. Cosmetic Derm 2005;18:31-6.
32. Marmur ES, Phelps R, Goldberg DJ. Ultrastructural changes seen after ALA-IPL photorejuvenation: a pilot study. J Cosmet Laser Ther 2005;7:21-4.
33. Dover JS, Bhatia AC, Stewart B, Arndt KA. Topical 5-aminolevulinic acid combined with intense pulsed light in the treatment of photoaging. Arch Dermatol 2005;141:1247-52.
34. Gold MH, Bradshaw VL, Boring MM, Bridges TM, Biron JA. Split-face comparison of photodynamic therapy with 5-aminolevulinic acid and intense pulsed light versus intense pulsed light alone for photodamage. Dermatol Surg 2006;32:795-801.
35. Zane C, Capezzera R, Sala R, Venturini M, Calzavara-Pinton P. Clinical and echographic analysis of photodynamic therapy using methylaminolevulinate as sensitizer in the treatment of photodamaged facial skin. Lasers Surg Med 2007;39:203-9.
36. Leyden JJ. Therapy for acne vulgaris. N Engl J Med 1997;336:1156-62.
37. Gollnick H, Cunliffe W, Berson D, Dreno B, Finlay A, Leyden JJ et al. Management of acne: a report from a Global Alliance to Improve Outcomes in Acne. J Am Acad Dermatol 2003;49 (1 Suppl):S1-S37.
38. Velicer CM, Heckbert SR, Lampe JW, Potter JD, Robertson CA, Taplin SH. Antibiotic use in relation to the risk of breast cancer. JAMA 2004;291:827-35.
39. Hongcharu W, Taylor CR, Chang Y, Aghassi D, Suthamjariya K, Anderson RR. Topical ALA-photodynamic therapy for the treatment of acne vulgaris. J Invest Dermatol 2000;115:183-92.
40. Itoh Y, Ninomiya Y, Tajima S, Ishibashi A. Photodynamic therapy for acne vulgaris with topical 5-aminolevulinic acid. Arch Dermatol 2000;136:1093-5.
41. Itoh Y, Ninomiya Y, Tajima S, Ishibashi A. Photodynamic therapy of acne vulgaris with topical delta aminolevulinic acid and incoherent light in Japanese patients. Br J Dermatol 2001;144:575-9.
42. Goldman MP, Boyce S. A single-center study of aminolevulinic acid and 417 nm photodynamic therapy in the treatment of moderate to severe acne vulgaris. J Drugs Dermatol 2003;2:393-6.
43. Gold, MH. The use of a novel intense pulsed light and heat source and ALA-PDT in the treatment of moderate to severe inflammatory acne vulgaris. J Drugs Dermatol 2004:3:S14-8.
44. Goldman MP, Gold MH, Rao J, Bridges TM, Bradshaw VL, Boring MM et al. A multicenter clinical evaluation of the treatment of mild to moderate inflammatory acne vulgaris of the face with visible blue light in comparison to topical 1% clindamycin antibiotic solution. J Drugs Dermatol 2005;4:64-70.
45. Taub AF. PDT for the treatment of acne: a pilot study. J Drugs Dermatol 2004;3:S10-4.
46. Alexiades-Armenakas M. Long-pulsed dye laser-mediated photodynamic therapy combined with topical therapy for mild to severe comedonal, inflammatory, or cystic acne. J Drugs Dermatol 2006;5:45-55.
47. Miller A, Van Camp A. Treatment of acne vulgaris with photodynamic therapy: the use of aminolevulinic acid and green light. Cosm Derm 2006;19:10:624-7.
48. Santos AV, Belo VG, G Santos. Effectiveness of photodynamic therapy with topical 5-Aminolevulinic acid and intense pulsed light versus intense pulsed light along in the treatment of acne vulgaris: comparative study. Dermatol Surg 2005;31(8 Pt 1):910-5.
49. Rojanamatin J, Choawawanich P. Treatment of inflammatory facial acne vulgaris with intense pulsed light and short contact of topical 5-aminolevulinic acid: a pilot study. Dermatol Surg 2006;32:991-6; discussion 996-7.
50. Wiegell SR, Wulf HC. Photodynamic therapy of acne vulgaris using methyl aminolevulinate: a blinded, randomized, controlled trial. Br J Dermatol 2006;154:969-76.
51. Horfelt C, Funk J, Frohm-Nilsson M. Topical methyl aminolevulinate photodynamic therapy for treatment of facial acne vulgaris: results of a randomized, controlled study. Br J Dermatol 2006;155:608-13.
52. Horio T, Horio O, Miyauchi-Hashimoto H, Ohnuki M, Isei T. Photodynamic therapy of sebaceous hyperplasia with topical 5-aminolevulinic acid and slide projector. Br J Dermatol 2003;148:1274-6.
53. Alster TS, Tanzi EL. Photodynamic therapy with topical aminolevulinic acid and pulsed dye laser irradiation for sebaceous hyperplasia. J Drugs Dermatol 2003;2:501-4.
54. Richey DF. Aminolevulinic acid photodynamic therapy for sebaceous gland hyperplasia. Dermatol Clin 2007;25:59-65.
55. Gold MH. A single center, open label investigator study of photodynamic therapy in the treatment of sebaceous gland hyperplasia with topical 20% 5-aminolevulinic acid with visible blue light or intense pulsed light. J Am Acad Derm 2004,50 Suppl:P638.
56. Gold MH, Bridges TM, Bradshaw VL, Boring M. ALA/PDT and blue light therapy for hidradenitis suppurativa. J Drugs Dermatol 2004;3:S32-39.
57. Strauss RM, Pollock B, Stables GI, Goulden V, Cunliffe WJ. Photodynamic therapy using aminolevulinic acid does not lead to clinical improvement in hidradenitis suppurativa. Br J Dermatol 2005;152: 803-4.
58. Rivard J, Ozog D. Henry Ford Hospital dermatology experience with Levulan Kerastick and blue light photodynamic therapy. J Drugs Dermatol 2006;5:556-61.
59. Gold, MH, Nestor MS. Current treatments of actinic keratosis. J Drugs Dermatol 2006; 5(2 Suppl):17-25.
60. Gold MH, Biron JA, Boring M, Bridges TM, Bradshaw VL. Treatment of moderate to severe inflammatory acne vulgaris: photodynamic therapy with 5-aminolevulinic acid and a novel advanced fluorescence technology pulsed light source. J Drugs Dermatol 2007;6:319-22.
61. Fang JY, Lee WR, Shen SC, Fang YP, Hu CH. Enhancement of topical 5-aminolevulinic acid delivery by Erbium: YAG laser and microdermabrasion: a comparison with iontophoresis and electroporation. Br J Dermatol 2004;151:132-40.
62. Gold, MH, Biron JA. A novel skin cream containing a mixture of human growth factors and cytokines for the treatment of adverse events associated with photodynamic therapy. J Drugs Dermatol 2006;5:796-8.
63. Gold MH. Single-center, split-face, double-blind, randomized clinical trial of the efficacy of a trolamine-containing topical emulsion and a topical petrolatum-based product in reducing redness and peeling after treatment with a microlaser peel. Poster Presentation American of Academy Dermatology Annual meeting 2006, March 3-7, San Francisco, CA.
64. Gold MH, Ribet V, Gral N et al. Calming efficacy and tolerance of avene spring water gel after epilatory laser treatment combined to healing cream in adults. Poster Presentation American of Academy Dermatology Annual meeting 2006, March 3-7, San Francisco, CA.