Blocking HDACs boosts regulatory T cells

Nature Medicine

Volumn 13, Issue 11, 2007, Pages 1282-1284

  Reddy, Pavan ^a   Zou, Weiping ^a  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; HISTONE; HISTONE DEACETYLASE INHIBITOR;

B LYMPHOCYTE; CD4+ T LYMPHOCYTE; HUMAN; IMMUNOLOGICAL TOLERANCE; KILLER CELL; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; SHORT SURVEY;

ANIMALS; CELL PROLIFERATION; ENZYME INHIBITORS; HISTONE DEACETYLASES; LYMPHOCYTE COUNT; MICE; REPRESSOR PROTEINS; T-LYMPHOCYTES, REGULATORY;

EID: 35948990782     PISSN: 10788956     EISSN: 1546170X     Source Type: Journal    
DOI: 10.1038/nm1107-1282     Document Type: Short Survey

References (15)

1. Zheng, Y. & Rudensky, A.Y. Nat. Immunol. 8, 457-462 (2007).
2. Bluestone, J.A. Nat. Rev. Immunol. 5, 343-349 (2005).
3. Tao, R., et al. Nat. Med. 13, 1299-1307 (2007).
4. Bolden, J.E., Peart, M.J. & Johnstone, R.W. Nat. Rev. Drug Discov. 5, 769-784 (2006).
5. Leoni, F. et al. Proc. Natl. Acad. Sci. USA 99, 2995-3000 (2002).
6. Mishra, N., Reilly, C.M., Brown, D.R., Ruiz, P. & Gilkeson, G.S. J. Clin. Invest. 111, 539-552 (2003).
7. Reddy, P. et al. Proc. Natl. Acad. Sci. USA 101, 3921-3926 (2004).
8. Chen, C., Rowell, E.A., Thomas, R.M., Hancock, W.W. & Wells, A.D. J. Biol. Chem. 281, 36828-36834 (2006).
9. Floess, S. et al. PLoS Biol. 5, e38 (2007).
10. Zheng, Y. et al. Nature 445, 936-940 (2007).
11. Wu, Y. et al. Cell 126, 375-387 (2006).
12. Ono, M. et al. Nature 446, 685-689 (2007).
13. Li, B. et al. Proc. Natl. Acad. Sci. USA 104, 4571-4576 (2007).
14. Allan, S.E. et al. J. Clin. Invest. 115, 3276-3284 (2005).
15. Brogdon, J.L. et al. Blood 109, 1123-1130 (2006).