Real-time spectral domain Doppler optical coherence tomography and investigation of human retinal vessel autoregulation

Journal of Biomedical Optics

Volumn 12, Issue 4, 2007, Pages

  Bower, Bradley A ^a   Zhao, Mingtao ^a   Zawadzki, Robert J ^b   Izatt, Joseph A ^a  

^a Duke University   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Biomedical optics; Doppler effect; Laser Doppler velocimetry; Ophthalmology; Real time imaging; Tomography

Indexed keywords

ALGORITHM; ARTICLE; BLOOD FLOW VELOCITY; COMPUTER ASSISTED DIAGNOSIS; COMPUTER SYSTEM; HEMOSTASIS; HISTOLOGY; HUMAN; IMAGE ENHANCEMENT; METHODOLOGY; OPTICAL COHERENCE TOMOGRAPHY; OXIMETRY; PHYSIOLOGY; REPRODUCIBILITY; RETINA BLOOD VESSEL; RETINOSCOPY; SENSITIVITY AND SPECIFICITY;

ALGORITHMS; BLOOD FLOW VELOCITY; COMPUTER SYSTEMS; HEMOSTASIS; HUMANS; IMAGE ENHANCEMENT; IMAGE INTERPRETATION, COMPUTER-ASSISTED; OXIMETRY; REPRODUCIBILITY OF RESULTS; RETINAL VESSELS; RETINOSCOPY; SENSITIVITY AND SPECIFICITY; TOMOGRAPHY, OPTICAL COHERENCE;

BLOOD VESSELS; DOPPLER EFFECT; MEDICAL IMAGING; OPHTHALMOLOGY; REAL TIME SYSTEMS;

OXYGEN INHALATION; RETINAL VESSEL AUTOREGULATION; SPECTRAL DOMAIN DOPPLER OPTICAL COHERENCE TOMOGRAPHY;

OPTICAL TOMOGRAPHY;

EID: 35948976154     PISSN: 10833668     EISSN: 15602281     Source Type: Journal    
DOI: 10.1117/1.2772877     Document Type: Article

References (38)

1. N. A. Nassif, B. Cense, B. H. Park, M. C. Pierce, S. H. Yun, B. E. Bouma, G. J. Tearney, T. C. Chen, and J. F. de Boer, "In vivo highresolution video-rate spectral-domain optical coherence tomography of the human retina and optic nerve," Opt. Express 12(3), 367-376 (2004).
2. M. Wojtkowski, V. J. Srinivasan, T. H. Ko, J. G. Fujimoto, A. Kowalczyk, and J. S. Duker, "Ultrahigh-resolution, high-speed, Fourier domain optical coherence tomography and methods for dispersion compensation," Opt. Express 12(11), 2404-2422 (2004).
3. Z. Chen, T. E. Milner, S. Srinivas, X. Wang, A. Malekafzali, M. J. C. v. Gemert, and J. S. Nelson, "Noninvasive imaging of in vivo blood flow velocity using optical Doppler tomography," Opt. Lett. 22, 1119-1121 (1997). (Pubitemid 127562050)
4. J. A. Izatt, M. D. Kulkarni, S. Yazdanfar, J. K. Barton, and A. J. Welch, "In vivo bidirectional color doppler flow imaging of picoliter blood volumes using optical coherence tomography," Opt. Lett. 22(18), 1439-1441 (1997). (Pubitemid 127565229)
5. V. X. D. Yang, M. L. Gordon, S. J. Tang, N. E. Marcon, G. Gardiner, B. Qi, S. Bisland, E. Seng-Yue, S. Lo, J. Pekar, B. C. Wilson, and I. A. Vitkin, "High speed, wide velocity dynamic range Doppler optical coherence tomography -Part 3): in vivo endoscopic imaging of blood flow in the rat and human gastrointestinal tracts," Opt. Express 11(19), 2416-2424 (2003).
6. S. Yazdanfar, A. M. Rollins, and J. A. Izatt, "In vivo imaging of human retinal flow dynamics by color -Doppler optical coherence tomography," Arch. Ophthalmol. (Chicago) 121, 235-239 (2003). (Pubitemid 36184037)
7. B. R. White, M. C. Pierce, N. Nassif, B. Cense, B. H. Park, G. J. Tearney, B. E. Bouma, T. C. Chen, and J. F. de Boer, "In vivo dynamic human retinal blood flow imaging using ultra-high-speed spectral domain optical Doppler tomography," Opt. Express 11(25), 3490-3497 (2003).
8. R. A. Leitgeb, L. Schmetterer, W. Drexler, A. F. Fercher, R. J. Zawadzki, and T. Bajraszewski, "Real-time assessment of retinal blood flow with ultrafast acquisition by color Doppler Fourier domain optical coherence tomography," Opt. Express 11(23), 3116-3121 (2003).
9. R. Leitgeb, L. F. Schmetterer, M. Wojtkowski, C. K. Hitzenberger, M. Sticker, and A. F. Fercher, "Flow velocity measurements by frequency domain short coherence interferometry," Proc. SPIE 4619, 16-21 (2002). (Pubitemid 35220411)
10. M. R. Hee, C. R. Baumal, C. A. Puliafito, J. S. Duker, E. Reichel, J. R. Wilkins, J. G. Coker, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Optical coherence tomography of age-related macular degeneration and choroidal neovascularization," Ophthalmology 103(8), 1260-1270 (1996). (Pubitemid 26282510)
11. M. R. Hee, C. A. Puliafito, C. Wong, J. S. Duker, E. Reichel, B. Rutledge, J. S. Schuman, E. A. Swanson, and J. G. Fujimoto, "Quantitative assessment of macular edema with optical coherence tomography," Arch. Ophthalmol. (Chicago) 113(8), 1019-1029 (1995).
12. W. Goebel and T. Kretzchmar-Gross, "Retinal thickness in diabetic retinopathy-A study using optical coherence tomography -OCT)," Retina J. Retinal Vitreous Diseases 22(6), 759-767 (2002). (Pubitemid 35462506)
13. M. J. Dumskyj, J. E. Eriksen, C. J. Dore, and E. M. Kohner, "Autoregulation in the human retinal circulation: assessment using isometric exercise, laser Doppler velocimetry, and computer-assisted image analysis," Microvasc. Res. 51, 378-392 (1996).
14. T. A. Deutsch, J. S. Read, J. T. Ernest, and T. K. Goldstick, "Effects of oxygen and carbon dioxide on the retinal vasculature in humans," Arch. Ophthalmol. (Chicago) 101, 1278-1280 (1983). (Pubitemid 13030949)
15. M. Langhans, G. Michelson, and M. J. M. Groh, "Effect of breathing 100% oxygen on retinal and optic nerve head capillary blood flow in smokers and non-smokers," Br. J. Ophthamol. pp. 365-369 (1997). (Pubitemid 27271852)
16. E. M. Kohner, V. Patel, and S. M. B. Rassam, "Role of blood-flow and impaired autoregulation in the pathogenesis of diabeticretinopathy," Diabetes 44(6), 603-607 (1995).
17. J. E. Grunwald, C. E. Riva, A. J. Brucker, S. H. Sinclair, and B. L. Petrig, "Altered retinal vascular-response to 100-percent oxygen breathing in diabetes-mellitus," Ophthalmology 91(12), 1447-1452 (1984). (Pubitemid 15197014)
18. M. A. Choma, M. V. Sarunic, C. H. Yang, and J. A. Izatt, "Sensitivity advantage of swept source and Fourier domain optical coherence tomography," Opt. Express 11(18), 2183-2189 (2003).
19. A. F. Fercher, C. K. Hitzenberger, G. Kamp, and S. Y. Elzaiat, "Measurement of intraocular distances by backscattering spectral interferometry," Opt. Commun. 117(43), 183-188 (1995).
20. G. Hausler and M. W. Lindner, "Coherence radar and spectral radar-new tools for dermatological diagnosis," J. Biomed. Opt. 3, 21 1998).
21. S. H. Yun, G. J. Tearney, B. E. Bouma, B. H. Park, and J. F. de Boer, "High-speed spectral-domain optical coherence tomography at 1.3 -m wavelength," Opt. Express 11(26), 3598-3604 (2003).
22. R. Leitgeb, C. K. Hitzenberger, and A. F. Fercher, "Performance of Fourier domain vs. time domain optical coherence tomography," Opt. Express 11(8), 889-894 (2003).
23. A. G. Podoleanu, J. A. Rogers, and D. A. Jackson, "OCT en face images from the retina with adjustable depth resolution in real time," IEEE J. Sel. Top. Quantum Electron. 5(4), 1176-1184 (1999). (Pubitemid 30544919)
24. S. L. Jiao, R. Knighton, X. R. Huang, G. Gregori, and C. A. Puliafito, "Simultaneous acquisition of sectional and fundus ophthalmic images with spectral-domain optical coherence tomography," Opt. Express 13(2), 444-452 (2005). (Pubitemid 40224918)
25. L. Wang, Y. Wang, S. Guo, J. Zhang, M. Bachman, G. P. Li, and Z. Chen, "Frequency domain phase-resolved optical Doppler and Doppler variance tomography," Opt. Commun. 242, 345-350 (2004).
26. M. A. Choma, A. K. Ellerbee, S. Yazdanfar, and J. A. Izatt, "Doppler flow imaging of cytoplasmic streaming using spectral domain phase microscopy," J. Biomed. Opt. 11(2), 024014 (2006).
27. B. H. Park, M. C. Pierce, B. Cense, and J. F. de Boer, "Real-time multi-functional optical coherence tomography," Opt. Express 11(7), 782-793 (2003).
28. A. M. Rollins, S. Yazdanfar, J. K. Barton, and J. A. Izatt, "Real-time in vivo color Doppler optical coherence tomography," -submitted for publication).
29. S. Yazdanfar, M. D. Kulkarni, and J. A. Izatt, "High resolution imaging of in vivo cardiac dynamics using color Doppler optical coherence tomography," Opt. Express 1(13), 424-431 (1997).
30. R. Halir and J. Flusser, "Numerically stable direct least squares fitting of ellipses," Proc. Intl. Conf. Central Europe Computer Graphics, Visual. Interactive Digital Media, pp. 125-132 (1998).
31. D. Hanselman, "Stable direct least squares ellipse fit," Matlab Central File Exchange, Matlab, Inc., Natick, MA (2005).
32. J. Ludovico, R. Bernardes, I. Pires, J. Figueira, C. Lobo, and J. Cunha-Vaz, "Alterations of retinal capillary blood flow in preclinical retinopathy in subjects with type 2 diabetes," Graefe's Arch. Clin. Exp. Ophthalmol. 241(3), 181-186 (2003). (Pubitemid 36747810)
33. R. K. Ghanta, A. Harris, E. Hertzmark, H. Pakter, J. Simpson, V. R. F. Guedes, W. Drexler, J. G. Fujimoto, L. Kagemann, and J. S. Schuman, "Evaluation of retinal blood flow using the Heidelberg Retina Flowmeter and nerve fiber layer thickness using optical coherence tomography in a glaucomatous monkey model," Invest. Ophthalmol. Visual Sci. 42(4), S15-S15 (2001).
34. M. H. M. Cuypers, J. S. Kasanardjo, and B. C. P. Polak, "Retinal blood flow changes in diabetic retinopathy measured with the Heidelberg scanning laser Doppler flowmeter," Graefe's Arch. Clin. Exp. Ophthalmol. 238(12), 935-941 (2000). (Pubitemid 32000755)
35. G. Michelson, B. Schmauss, M. J. Langhans, J. Harazny, and M. J. M. Groh, "Principle, validity, and reliability of scanning laser Doppler flowmetry," J. Glaucoma 5(2), 99-105 (1996). (Pubitemid 26139160)
36. P. Lundmark, M. Rawji, J. Flanagan, and G. Trope, "Variability of blood flow measurements using the Heidelberg retinal flowmeter.," Invest. Ophthalmol. Visual Sci. 37(3), 1215-1215 (1996).
37. H. Chen, C. Hudson, S. Ataullah, and D. McLeod, "The acute effect of smoking on retinal blood flow: An assessment with the Heidelberg retina flowmeter," Invest. Ophthalmol. Visual Sci. 37(3), 1237-1237 (1996).
38. D. X. Hammer, R. D. Ferguson, J. C. Magill, L. A. Paunescu, S. Beaton, H. Ishikawa, G. Wollstein, and J. S. Schuman, "Active retinal tracker for clinical optical coherence tomography systems," J. Biomed. Opt. 10(2), 024038 (2005).